Xeon E5-2643 v3 vs Xeon Silver 4110

Intel

Xeon E5-2643 v3

6 Cores12 Thrd135 WWMax: 3.7 GHz2014
Similar parts
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VS
Intel

Xeon Silver 4110

8 Cores16 Thrd85 WWMax: 3 GHz2017
Similar parts
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Xeon E5-2643 v3 vs Xeon Silver 4110 Performance Spectrum

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Xeon E5-2643 v3 vs Xeon Silver 4110 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Xeon E5-2643 v3 vs Xeon Silver 4110: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Xeon E5-2643 v3

2014

Why buy it

  • +81.8% larger total L3 cache (20 MB vs 11 MB).

Trade-offs

  • Lower PassMark (10,265 vs 10,314).
  • Launch MSRP is still $219 MSRP, while Xeon Silver 4110 mostly shows up through inconsistent older-market listings.
  • 58.8% higher power demand at 135W vs 85W.

Xeon Silver 4110

2017

Why buy it

  • +0.5% higher PassMark.
  • Draws 85W instead of 135W, a 50W reduction.
  • 100+% more PCIe lanes (48 vs 0) for storage and expansion-heavy builds.

Trade-offs

  • Smaller total L3 cache (11 MB vs 20 MB).

Quick Answers

So, is Xeon Silver 4110 better than Xeon E5-2643 v3?
It depends on what you want from the system. For gaming, Xeon E5-2643 v3 is ahead with a 1.0% average FPS lead across 50 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, Xeon Silver 4110 pulls ahead with 0.5% better PassMark. Xeon E5-2643 v3 also has the bigger cache pool with 81.8% larger total L3 cache (20 MB vs 11 MB).
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, Xeon Silver 4110 is the stronger fit. You are getting 0.5% better PassMark, backed by 8 cores and 16 threads.
Which one is the smarter buy today, not just the cheaper CPU?
Xeon Silver 4110 is still the faster CPU overall, but Xeon E5-2643 v3 is easier to justify if budget matters more than peak performance. Xeon Silver 4110 comes in at an unclear MSRP at unclear MSRP versus $219 MSRP, and it still gives you 0.5% better PassMark. The compromise is that Xeon E5-2643 v3 is still the better pure gaming CPU with a 1.0% average FPS lead across 50 shared CPU game tests in our data. Xeon E5-2643 v3 is also 100.0% better value on MSRP (46.9 vs 0.0 PassMark/$), which is why it can still make sense for tighter-budget builds on paper.
Which one is more future-proof for 2026 and beyond?
Xeon Silver 4110 makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2017 vs 2014), more multi-core headroom with 8 cores / 16 threads instead of 6/12, and AVX-512 support for heavier modern compute workloads. That extra compute headroom is more likely to matter as games, background tasks, and creator workloads get heavier.

Xeon E5-2643 v3 vs Xeon Silver 4110 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Intel

Xeon E5-2643 v3

The Xeon E5-2643 v3 is manufactured by Intel. It was released in 2015-01-01. It is based on the Haswell-EP (2014−2015) architecture. It features 6 cores and 12 threads. Base frequency is 3.4 GHz, with boost up to 3.7 GHz. L3 cache: 20 MB (total). L2 cache: 256K (per core). Built on 22 nm process technology. Socket: LGA2011. Thermal design power (TDP): 135 Watt. Memory support: DDR4-1600, DDR4-1866, DDR4-2133. Passmark benchmark score: 10,265 points. Launch price was $800.

Intel

Xeon Silver 4110

The Xeon Silver 4110 is manufactured by Intel. It was released in 11 July 2017 (8 years ago). It is based on the Skylake (server) (2017−2018) architecture. It features 8 cores and 16 threads. Base frequency is 2.1 GHz, with boost up to 3 GHz. L3 cache: 11 MB. L2 cache: 8 MB. Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 85 Watt. Memory support: DDR4-2400. Passmark benchmark score: 10,314 points. Launch price was $501.

Processing Power

The Xeon E5-2643 v3 packs 6 cores / 12 threads, while the Xeon Silver 4110 offers 8 cores / 16 threads — the Xeon Silver 4110 has 2 more cores. Boost clocks reach 3.7 GHz on the Xeon E5-2643 v3 versus 3 GHz on the Xeon Silver 4110 — a 20.9% clock advantage for the Xeon E5-2643 v3 (base: 3.4 GHz vs 2.1 GHz). The Xeon E5-2643 v3 uses the Haswell-EP (2014−2015) architecture (22 nm), while the Xeon Silver 4110 uses Skylake (server) (2017−2018) (14 nm). In PassMark, the Xeon E5-2643 v3 scores 10,265 against the Xeon Silver 4110's 10,314 — a 0.5% lead for the Xeon Silver 4110. L3 cache: 20 MB (total) on the Xeon E5-2643 v3 vs 11 MB on the Xeon Silver 4110.

FeatureXeon E5-2643 v3Xeon Silver 4110
Cores / Threads
6 / 12
8 / 16+33%
Boost Clock
3.7 GHz+23%
3 GHz
Base Clock
3.4 GHz+62%
2.1 GHz
L3 Cache
20 MB (total)+82%
11 MB
L2 Cache
256K (per core)+3100%
8 MB
Process
22 nm
14 nm-36%
Architecture
Haswell-EP (2014−2015)
Skylake (server) (2017−2018)
PassMark
10,265
10,314
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Memory & Platform

The Xeon E5-2643 v3 uses the LGA2011 socket (PCIe 5.0), while the Xeon Silver 4110 uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard.

FeatureXeon E5-2643 v3Xeon Silver 4110
Socket
LGA2011
LGA3647
PCIe Generation
PCIe 5.0+67%
PCIe 3.0
Max RAM Speed
2400
Max RAM Capacity
1024
RAM Channels
6
ECC Support
Yes
PCIe Lanes
48
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Advanced Features

Virtualization: not specified (Xeon E5-2643 v3) / VT-x, VT-d (Xeon Silver 4110).

FeatureXeon E5-2643 v3Xeon Silver 4110
Integrated GPU
No
IGPU Model
None
Unlocked
No
AVX-512
Yes
Virtualization
VT-x, VT-d