Xeon Gold 6421N vs Xeon W-3375

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Xeon Gold 6421N vs Xeon W-3375 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Xeon Gold 6421N vs Xeon W-3375: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Xeon Gold 6421N

2023

Why buy it

✅Costs $2,583 less on MSRP ($2,368 MSRP vs $4,951 MSRP).
✅Delivers 108.0% more PassMark for each dollar spent, at 24.8 vs 11.9 PassMark/$ ($2,368 MSRP vs $4,951 MSRP).
✅Draws 185W instead of 270W, a 85W reduction.
✅Newer platform on LGA4677 with DDR5 support instead of LGA4189 and DDR4.
✅25% more PCIe lanes (80 vs 64) for storage and expansion-heavy builds.

Trade-offs

❌Lower PassMark (58,797 vs 59,091).

Xeon W-3375

2021

Why buy it

Trade-offs

❌Lower PassMark per dollar, at 11.9 vs 24.8 PassMark/$ ($4,951 MSRP vs $2,368 MSRP).
❌45.9% higher power demand at 270W vs 185W.
❌Older platform position on LGA4189 with DDR4, while Xeon Gold 6421N moves to LGA4677 and DDR5.

Quick Answers

So, is Xeon W-3375 better than Xeon Gold 6421N?

Yes. Xeon W-3375 is the better all-around CPU here. It gives you a 2.8% average FPS lead across 50 shared CPU game tests in our data and 0.5% better PassMark, which is enough to make it the stronger overall pick.

Which one is better for gaming?

If gaming is the priority, Xeon W-3375 is the better pick. According to our tests, it delivers 2.8% more average FPS across 50 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon W-3375 is the stronger fit. You are getting 0.5% better PassMark, backed by 38 cores and 76 threads.

Which one is the smarter buy today, not just the cheaper CPU?

Xeon W-3375 is still the faster CPU overall, but Xeon Gold 6421N is easier to justify if budget matters more than peak performance. Xeon W-3375 comes in 109.1% more expensive on MSRP at $4,951 MSRP versus $2,368 MSRP, and it still gives you a 2.8% average FPS lead across 50 shared CPU game tests in our data. Xeon Gold 6421N is also 108.0% better value on MSRP (24.8 vs 11.9 PassMark/$), which is why it can still make sense for tighter-budget builds on paper.

Which one is more future-proof for 2026 and beyond?

Xeon Gold 6421N makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2023 vs 2021) and a healthier platform with LGA4677 and DDR5 instead of LGA4189. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

Xeon Gold 6421N vs Xeon W-3375 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Xeon Gold 6421N

The Xeon Gold 6421N is manufactured by Intel. It was released in 10 January 2023 (2 years ago). It is based on the Sapphire Rapids (2023−2024) architecture. It features 32 cores and 64 threads. Base frequency is 1.8 GHz, with boost up to 3.6 GHz. L3 cache: 60 MB. L2 cache: 2 MB (per core). Built on Intel 7 nm process technology. Socket: LGA4677. Thermal design power (TDP): 185 Watt. Memory support: DDR5-4400. Passmark benchmark score: 58,797 points. Launch price was $2,368.

Xeon W-3375

The Xeon W-3375 is manufactured by Intel. It was released in 2021-07-29. It is based on the Ice Lake-W (2021) architecture. It features 38 cores and 76 threads. Base frequency is 2.5 GHz, with boost up to 4 GHz. L3 cache: 57 MB (total). L2 cache: 1 MB (per core). Built on 10 nm process technology. Socket: LGA4189. Thermal design power (TDP): 270 Watt. Memory support: DDR4-3200. Passmark benchmark score: 59,091 points. Launch price was $4,499.

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Processing Power

The Xeon Gold 6421N packs 32 cores / 64 threads, while the Xeon W-3375 offers 38 cores / 76 threads — the Xeon W-3375 has 6 more cores. Boost clocks reach 3.6 GHz on the Xeon Gold 6421N versus 4 GHz on the Xeon W-3375 — a 10.5% clock advantage for the Xeon W-3375 (base: 1.8 GHz vs 2.5 GHz). The Xeon Gold 6421N uses the Sapphire Rapids (2023−2024) architecture (Intel 7 nm), while the Xeon W-3375 uses Ice Lake-W (2021) (10 nm). In PassMark, the Xeon Gold 6421N scores 58,797 against the Xeon W-3375's 59,091 — a 0.5% lead for the Xeon W-3375. L3 cache: 60 MB on the Xeon Gold 6421N vs 57 MB (total) on the Xeon W-3375.

Feature	Xeon Gold 6421N	Xeon W-3375
Cores / Threads	32 / 64	38 / 76+19%
Boost Clock	3.6 GHz	4 GHz+11%
Base Clock	1.8 GHz	2.5 GHz+39%
L3 Cache	60 MB+5%	57 MB (total)
L2 Cache	2 MB (per core)+100%	1 MB (per core)
Process	Intel 7 nm-30%	10 nm
Architecture	Sapphire Rapids (2023−2024)	Ice Lake-W (2021)
PassMark	58,797	59,091
Geekbench 6 Single	—	1,818
Geekbench 6 Multi	—	17,713

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Memory & Platform

The Xeon Gold 6421N uses the LGA4677 socket (PCIe 5.0), while the Xeon W-3375 uses LGA4189 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 4800 on the Xeon Gold 6421N versus DDR4-3200 on the Xeon W-3375 — the Xeon Gold 6421N supports 50% faster memory, which can translate to measurable gains in memory-sensitive workloads. Both support up to 4096 GB of RAM. Both feature 8-channel memory with ECC support. PCIe lanes: 80 (Xeon Gold 6421N) vs 64 (Xeon W-3375) — the Xeon Gold 6421N offers 16 more lanes for additional GPUs or NVMe drives. Chipset compatibility: C741 (Xeon Gold 6421N) and Intel C621A (Xeon W-3375).

Feature	Xeon Gold 6421N	Xeon W-3375
Socket	LGA4677	LGA4189
PCIe Generation	PCIe 5.0+25%	PCIe 4.0
Max RAM Speed	4800+50%	DDR4-3200
Max RAM Capacity	4096 GB	4096 GB
RAM Channels	8	8
ECC Support	Yes	Yes
PCIe Lanes	80+25%	64

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Advanced Features

Neither processor supports overclocking. Both support AVX-512 instructions, benefiting scientific computing, AI inference, and encryption workloads. Virtualization support: VT-x, VT-d (Xeon Gold 6421N) vs true (Xeon W-3375). Direct competitor: Xeon Gold 6421N rivals EPYC 9354; Xeon W-3375 rivals EPYC 7543.

Feature	Xeon Gold 6421N	Xeon W-3375
Integrated GPU	No	No
IGPU Model	None	None
Unlocked	No	No
AVX-512	Yes	Yes
Virtualization	VT-x, VT-d	true

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Value Analysis

At launch, the Xeon Gold 6421N was priced at $2368, while the Xeon W-3375 came in at $4951. On launch pricing ($2368 vs $4951), Xeon Gold 6421N was $2583 cheaper. In terms of value on MSRP (PassMark points per dollar), the Xeon Gold 6421N delivers 24.8 pts/$ vs 11.9 pts/$ for the Xeon W-3375 — making the Xeon Gold 6421N the 70.1% better value option.

Feature	Xeon Gold 6421N	Xeon W-3375
MSRP	$2368-52%	$4951
Performance per Dollar	24.8+108%	11.9
Release Date	2023	2021

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