Core i5-10400F vs EPYC 7643P

CPU

GPU

Core i5-10400F

6 Cores12 Thrd65 WWMax: 4.3 GHz2020

Popular choices:

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EPYC 7643P

48 Cores96 Thrd225 WWMax: 3.6 GHz2023

Popular choices:

•••••••••

Performance Spectrum - CPU

Core i5-10400F

6 / 12

13,029

0.0%

77,307

+493.3%

Ryzen AI Max PRO 390

Ryzen 9 9850HX

Ryzen Threadripper PRO 7955WX

Ryzen Threadripper PRO 9955WX

Ryzen Threadripper 9960X

Ryzen Threadripper 7970X

Ryzen Threadripper PRO 7985WX

Ryzen Threadripper 7980X

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

Core i5-10400F

2020

Why buy it

✅Costs $2,562 less on MSRP ($160 MSRP vs $2,722 MSRP).
✅Delivers 186.7% more PassMark for each dollar spent, at 81.4 vs 28.4 PassMark/$ ($160 MSRP vs $2,722 MSRP).
✅Draws 65W instead of 225W, a 160W reduction.
✅Includes a boxed cooler (Yes), unlike EPYC 7643P.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 7643P across 50 shared CPU benchmark tests.
❌Lower PassMark (13,029 vs 77,307).
❌Less compelling for workstation-style loads than EPYC 7643P, which brings 48 cores / 96 threads and 128 PCIe lanes.

EPYC 7643P

2023

Why buy it

✅Better for gaming: +20.7% higher average FPS across 50 shared CPU benchmark tests.
✅Better for workstations and heavier parallel workloads: 48 cores / 96 threads, plus 128 PCIe lanes vs 16.
✅700% more PCIe lanes (128 vs 16) for storage and expansion-heavy builds.

Trade-offs

❌Lower PassMark per dollar, at 28.4 vs 81.4 PassMark/$ ($2,722 MSRP vs $160 MSRP).
❌246.2% higher power demand at 225W vs 65W.
❌No boxed cooler included, unlike Core i5-10400F.

Core i5-10400F

2020

EPYC 7643P

2023

Why buy it

✅Costs $2,562 less on MSRP ($160 MSRP vs $2,722 MSRP).
✅Delivers 186.7% more PassMark for each dollar spent, at 81.4 vs 28.4 PassMark/$ ($160 MSRP vs $2,722 MSRP).
✅Draws 65W instead of 225W, a 160W reduction.
✅Includes a boxed cooler (Yes), unlike EPYC 7643P.

Why buy it

✅Better for gaming: +20.7% higher average FPS across 50 shared CPU benchmark tests.
✅Better for workstations and heavier parallel workloads: 48 cores / 96 threads, plus 128 PCIe lanes vs 16.
✅700% more PCIe lanes (128 vs 16) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 7643P across 50 shared CPU benchmark tests.
❌Lower PassMark (13,029 vs 77,307).
❌Less compelling for workstation-style loads than EPYC 7643P, which brings 48 cores / 96 threads and 128 PCIe lanes.

Trade-offs

❌Lower PassMark per dollar, at 28.4 vs 81.4 PassMark/$ ($2,722 MSRP vs $160 MSRP).
❌246.2% higher power demand at 225W vs 65W.
❌No boxed cooler included, unlike Core i5-10400F.

Quick Answers

So, is EPYC 7643P better than Core i5-10400F?

Not in a simple one-size-fits-all way. EPYC 7643P makes more sense for workstation-style multi-core throughput, while Core i5-10400F is the better mainstream desktop choice for gaming, platform cost, and day-to-day practicality.

Which one is better for gaming?

If gaming is the priority, EPYC 7643P is the better pick here. According to our tests, it delivers 20.7% more average FPS across 50 shared CPU game tests. It also has a big cache advantage at 256 MB vs 12 MB.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, EPYC 7643P is the better fit. You are getting 493.3% better PassMark, backed by 48 cores and 96 threads. It also carries the larger cache pool with 2033.3% larger total L3 cache (256 MB vs 12 MB).

Which one is the smarter buy today, not just the cheaper CPU?

EPYC 7643P is still the faster CPU overall, but Core i5-10400F makes more sense if price matters more than absolute performance. EPYC 7643P is 1601.3% more expensive on MSRP at $2,722 MSRP versus $160 MSRP, and it gives you a 20.7% average FPS lead across 50 shared CPU game tests in our data. Core i5-10400F is also 186.7% better value on MSRP (81.4 vs 28.4 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.

Which one is more future-proof for 2026 and beyond?

EPYC 7643P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2023 vs 2020), 3D V-Cache and a much larger 256 MB L3 cache instead of 12 MB, and more multi-core headroom with 48 cores / 96 threads instead of 6/12. That extra cache should hold up really well in CPU-limited games and high-refresh builds.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Core i5-10400F Benchmark Check

EPYC 7643P Benchmark Check

Path of Exile 2

Preset	Core i5-10400F	EPYC 7643P
1080p
low	192 FPS	195 FPS
medium	152 FPS	159 FPS
high	123 FPS	129 FPS
ultra	100 FPS	100 FPS
1440p
low	153 FPS	160 FPS
medium	119 FPS	125 FPS
high	97 FPS	97 FPS
ultra	79 FPS	77 FPS
4K
low	82 FPS	72 FPS
medium	70 FPS	60 FPS
high	55 FPS	47 FPS
ultra	43 FPS	39 FPS

Open Core i5-10400F Open EPYC 7643P

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	Core i5-10400F	EPYC 7643P
1080p
low	326 FPS	418 FPS
medium	318 FPS	367 FPS
high	290 FPS	299 FPS
ultra	253 FPS	234 FPS
1440p
low	326 FPS	344 FPS
medium	292 FPS	310 FPS
high	267 FPS	259 FPS
ultra	234 FPS	197 FPS
4K
low	309 FPS	211 FPS
medium	258 FPS	194 FPS
high	235 FPS	163 FPS
ultra	199 FPS	131 FPS

Open Core i5-10400F Open EPYC 7643P

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	Core i5-10400F	EPYC 7643P
1080p
low	326 FPS	837 FPS
medium	326 FPS	698 FPS
high	326 FPS	650 FPS
ultra	326 FPS	574 FPS
1440p
low	326 FPS	602 FPS
medium	326 FPS	500 FPS
high	326 FPS	458 FPS
ultra	326 FPS	401 FPS
4K
low	326 FPS	430 FPS
medium	326 FPS	336 FPS
high	289 FPS	300 FPS
ultra	229 FPS	243 FPS

Open Core i5-10400F Open EPYC 7643P

League of Legends

League of Legends

Valorant

Preset	Core i5-10400F	EPYC 7643P
1080p
low	326 FPS	979 FPS
medium	326 FPS	888 FPS
high	326 FPS	765 FPS
ultra	326 FPS	661 FPS
1440p
low	326 FPS	753 FPS
medium	326 FPS	657 FPS
high	326 FPS	562 FPS
ultra	326 FPS	482 FPS
4K
low	326 FPS	541 FPS
medium	326 FPS	481 FPS
high	326 FPS	423 FPS
ultra	326 FPS	365 FPS

Open Core i5-10400F Open EPYC 7643P

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of Core i5-10400F and EPYC 7643P

Core i5-10400F

The Core i5-10400F is manufactured by Intel. It was released in 30 April 2020 (5 years ago). It is based on the Comet Lake (2020−2025) architecture. It features 6 cores and 12 threads. Base frequency is 2.9 GHz, with boost up to 4.3 GHz. L3 cache: 12 MB (total). L2 cache: 256K (per core). Built on 14 nm process technology. Socket: LGA1200. Thermal design power (TDP): 65 Watt. Memory support: DDR4. Passmark benchmark score: 13,029 points. Launch price was $155.

EPYC 7643P

The EPYC 7643P is manufactured by AMD. It was released in 5 September 2023 (2 years ago). It is based on the Milan (2021−2023) architecture. It features 48 cores and 96 threads. Base frequency is 2.3 GHz, with boost up to 3.6 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4. Passmark benchmark score: 77,307 points. Launch price was $2,722.

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Processing Power

The Core i5-10400F packs 6 cores / 12 threads, while the EPYC 7643P offers 48 cores / 96 threads — the EPYC 7643P has 42 more cores. Boost clocks reach 4.3 GHz on the Core i5-10400F versus 3.6 GHz on the EPYC 7643P — a 17.7% clock advantage for the Core i5-10400F (base: 2.9 GHz vs 2.3 GHz). The Core i5-10400F uses the Comet Lake (2020−2025) architecture (14 nm), while the EPYC 7643P uses Milan (2021−2023) (7 nm). In PassMark, the Core i5-10400F scores 13,029 against the EPYC 7643P's 77,307 — a 142.3% lead for the EPYC 7643P. L3 cache: 12 MB (total) on the Core i5-10400F vs 256 MB (total) on the EPYC 7643P.

Feature	Core i5-10400F	EPYC 7643P
Cores / Threads	6 / 12	48 / 96+700%
Boost Clock	4.3 GHz+19%	3.6 GHz
Base Clock	2.9 GHz+26%	2.3 GHz
L3 Cache	12 MB (total)	256 MB (total)+2033%
L2 Cache	256K (per core)	512 kB (per core)+100%
Process	14 nm	7 nm-50%
Architecture	Comet Lake (2020−2025)	Milan (2021−2023)
PassMark	13,029	77,307+493%
Cinebench R23 Multi	8,191	—
Geekbench 6 Single	1,454	—
Geekbench 6 Multi	5,783	—

🧠

Memory & Platform

The Core i5-10400F uses the LGA1200 socket (PCIe 3.0), while the EPYC 7643P uses SP3 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches DDR4-2666 on the Core i5-10400F versus 3200 on the EPYC 7643P — the EPYC 7643P supports 199.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7643P supports up to 4096 of RAM compared to 128 GB — 187.9% more capacity for professional workloads. Memory channels: 2 (Core i5-10400F) vs 8 (EPYC 7643P). PCIe lanes: 16 (Core i5-10400F) vs 128 (EPYC 7643P) — the EPYC 7643P offers 112 more lanes for additional GPUs or NVMe drives. Chipset compatibility: H410,B460,H470,Z490,H510,B560,H570,Z590 (Core i5-10400F) and SP3 (EPYC 7643P).

Feature	Core i5-10400F	EPYC 7643P
Socket	LGA1200	SP3
PCIe Generation	PCIe 3.0	PCIe 4.0+33%
Max RAM Speed	DDR4-2666	3200+79900%
Max RAM Capacity	128 GB+3276700%	4096
RAM Channels	2	8+300%
ECC Support	No	Yes
PCIe Lanes	16	128+700%

🔧

Advanced Features

Neither processor supports overclocking. Virtualization support: VT-x, VT-d (Core i5-10400F) vs VT-x, VT-d, SEV (EPYC 7643P). Primary use case: Core i5-10400F targets Gaming. Direct competitor: Core i5-10400F rivals Ryzen 5 3600; EPYC 7643P rivals Xeon Platinum 8380.

Feature	Core i5-10400F	EPYC 7643P
Integrated GPU	No	No
IGPU Model	—	None
Unlocked	No	No
AVX-512	No	No
Virtualization	VT-x, VT-d	VT-x, VT-d, SEV
Target Use	Gaming	—

💰

Value Analysis

The Core i5-10400F launched at $160 MSRP, while the EPYC 7643P debuted at $2722. On MSRP ($160 vs $2722), the Core i5-10400F is $2562 cheaper. In terms of value on MSRP (PassMark points per dollar), the Core i5-10400F delivers 81.4 pts/$ vs 28.4 pts/$ for the EPYC 7643P — making the Core i5-10400F the 96.6% better value option.