EPYC 7543 vs EPYC 4565P
EPYC 7543
EPYC 4565P
Performance Spectrum - CPU
About PassMark
PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.
Value Upgrade Path
This is the official ChipVERSUS Value Rating, comparing raw performance (PassMark) per dollar. Components placed above yours deliver better value for money.
Avg price is the current average price collected from markets across the web.
Performance Per Dollar EPYC 7543
Performance Per Dollar EPYC 4565P
Performance Comparison
About PassMark🏆 Chipversus Verdict
🚀 Performance Leadership
| Insight | EPYC 7543 | EPYC 4565P |
|---|---|---|
| Gaming | ✅ Superior gaming performance | ❌ Lower gaming performance |
| Workstation | ❌ Weaker in multi-core tasks | ✅ Better multi-core power |
| Price | ✅ More affordable ($468) | ⚠️ Higher cost ($1,980) |
| Longevity | ✨ Modern (Milan (2021−2023) / 7 nm+) | ✨ Modern (Grado (2025) / 4 nm) |
💎 Value Proposition
| Insight | EPYC 7543 | EPYC 4565P |
|---|---|---|
| Cost Efficiency | ✅ Better overall value (+316%) | ❌ Lower cost efficiency |
| Upfront Cost | ✅ More affordable ($468) | ⚠️ Higher cost ($1,980) |
Performance Check
To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.
Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.
Technical Specifications
Side-by-side comparison of EPYC 7543 and EPYC 4565P
EPYC 7543
The EPYC 7543 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,952 points. Launch price was $3,761.
EPYC 4565P
The EPYC 4565P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 4.3 GHz, with boost up to 5.7 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 170 Watt. Memory support: DDR5. Passmark benchmark score: 64,068 points. Launch price was $589.
Processing Power
The EPYC 7543 packs 32 cores / 64 threads, while the EPYC 4565P offers 16 cores / 32 threads — the EPYC 7543 has 16 more cores. Boost clocks reach 3.7 GHz on the EPYC 7543 versus 5.7 GHz on the EPYC 4565P — a 42.6% clock advantage for the EPYC 4565P (base: 2.8 GHz vs 4.3 GHz). The EPYC 7543 uses the Milan (2021−2023) architecture (7 nm+), while the EPYC 4565P uses Grado (2025) (4 nm). In PassMark, the EPYC 7543 scores 62,952 against the EPYC 4565P's 64,068 — a 1.8% lead for the EPYC 4565P. L3 cache: 256 MB (total) on the EPYC 7543 vs 64 MB (total) on the EPYC 4565P.
| Feature | EPYC 7543 | EPYC 4565P |
|---|---|---|
| Cores / Threads | 32 / 64+100% | 16 / 32 |
| Boost Clock | 3.7 GHz | 5.7 GHz+54% |
| Base Clock | 2.8 GHz | 4.3 GHz+54% |
| L3 Cache | 256 MB (total)+300% | 64 MB (total) |
| L2 Cache | 512 kB (per core) | 1 MB (per core)+100% |
| Process | 7 nm+ | 4 nm-43% |
| Architecture | Milan (2021−2023) | Grado (2025) |
| PassMark | 62,952 | 64,068+2% |
Memory & Platform
The EPYC 7543 uses the SP3 socket (PCIe 4.0), while the EPYC 4565P uses AM5 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 3200 on the EPYC 7543 versus 5600 on the EPYC 4565P — the EPYC 4565P supports 54.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7543 supports up to 4096 of RAM compared to 192 — 182.1% more capacity for professional workloads. Memory channels: 8 (EPYC 7543) vs 2 (EPYC 4565P). PCIe lanes: 128 (EPYC 7543) vs 28 (EPYC 4565P) — the EPYC 7543 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: SP3 (EPYC 7543) and AM5 (EPYC 4565P).
| Feature | EPYC 7543 | EPYC 4565P |
|---|---|---|
| Socket | SP3 | AM5 |
| PCIe Generation | PCIe 4.0 | PCIe 4.0 |
| Max RAM Speed | 3200 | 5600+75% |
| Max RAM Capacity | 4096+2033% | 192 |
| RAM Channels | 8+300% | 2 |
| ECC Support | ✅ | ✅ |
| PCIe Lanes | 128+357% | 28 |
Advanced Features
Only the EPYC 4565P has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Only the EPYC 4565P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: VT-x, VT-d (EPYC 7543) vs VT-x, VT-d, AMD-V (EPYC 4565P). The EPYC 4565P includes integrated graphics (AMD Radeon Graphics), while the EPYC 7543 requires a dedicated GPU. Direct competitor: EPYC 7543 rivals Xeon Platinum 8380; EPYC 4565P rivals Core Ultra 9 285K.
| Feature | EPYC 7543 | EPYC 4565P |
|---|---|---|
| Integrated GPU | No | Yes |
| IGPU Model | None | AMD Radeon Graphics |
| Unlocked | No | Yes |
| AVX-512 | No | Yes |
| Virtualization | VT-x, VT-d | VT-x, VT-d, AMD-V |
Value Analysis
The EPYC 7543 launched at $10257 MSRP, while the EPYC 4565P debuted at $2730. At current prices ($468 vs $1980), the EPYC 7543 is $1512 cheaper. In terms of value (PassMark points per dollar), the EPYC 7543 delivers 134.5 pts/$ vs 32.4 pts/$ for the EPYC 4565P — making the EPYC 7543 the 122.4% better value option.
| Feature | EPYC 7543 | EPYC 4565P |
|---|---|---|
| MSRP | $10257 | $2730-73% |
| Avg Price (30d) | $468-76% | $1980 |
| Performance per Dollar | 134.5+315% | 32.4 |
| Release Date | 2021 | 2025 |
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