Opteron 6376 vs Xeon E3-1220 v6

Opteron 6376 vs Xeon E3-1220 v6 Performance Spectrum

Opteron 6376

16 / 16

5,572

0.0%

Ryzen Threadripper PRO 3975WX

Ryzen Threadripper PRO 7965WX

Xeon E3-1220 v6

4 / 4

5,589

+0.3%

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Opteron 6376 vs Xeon E3-1220 v6 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Opteron 6376 vs Xeon E3-1220 v6: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Opteron 6376

2012

Why buy it

✅Better for gaming: +24.4% higher average FPS across 42 shared CPU benchmark tests.

Trade-offs

❌Lower PassMark (5,572 vs 5,589).
❌Lower PassMark per dollar, at 7.9 vs 15.0 PassMark/$ ($703 MSRP vs $372 MSRP).
❌59.7% higher power demand at 115W vs 72W.

Xeon E3-1220 v6

2017

Why buy it

✅+0.3% higher PassMark.
✅Costs $331 less on MSRP ($372 MSRP vs $703 MSRP).
✅Delivers 89.6% more PassMark for each dollar spent, at 15.0 vs 7.9 PassMark/$ ($372 MSRP vs $703 MSRP).
✅Draws 72W instead of 115W, a 43W reduction.

Trade-offs

❌Worse for gaming: lower average FPS than Opteron 6376 across 42 shared CPU benchmark tests.

Quick Answers

So, is Xeon E3-1220 v6 better than Opteron 6376?

It depends on what you want from the system. For gaming, Opteron 6376 is ahead with a 24.4% average FPS lead across 42 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, Xeon E3-1220 v6 pulls ahead with 0.3% better PassMark.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon E3-1220 v6 is the stronger fit. You are getting 0.3% better PassMark, backed by 4 cores and 4 threads.

Which one is the smarter buy today, not just the cheaper CPU?

Xeon E3-1220 v6 is the better buy right now. Xeon E3-1220 v6 comes in $331 cheaper on MSRP at $372 MSRP versus $703 MSRP, and it still gives you 0.3% better PassMark. The compromise is that Opteron 6376 is still the better pure gaming CPU with a 24.4% average FPS lead across 42 shared CPU game tests in our data. It is also 89.6% better value on MSRP (15.0 vs 7.9 PassMark/$), so you are getting the faster CPU without taking a value hit on paper.

Which one is more future-proof for 2026 and beyond?

Xeon E3-1220 v6 makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2017 vs 2012) and more multi-core headroom with 4 cores / 4 threads instead of 16/16. That extra compute headroom is more likely to matter as games, background tasks, and creator workloads get heavier.

Opteron 6376 vs Xeon E3-1220 v6 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Opteron 6376

The Opteron 6376 is manufactured by AMD. It was released in 5 November 2012 (13 years ago). It is based on the Abu Dhabi (2012) architecture. It features 16 cores and 16 threads. Base frequency is 2.3 GHz, with boost up to 3.2 GHz. L3 cache: 8 MB (total). L2 cache: 16 MB. Built on 32 nm process technology. Socket: G34. Thermal design power (TDP): 115 Watt. Memory support: DDR3. Passmark benchmark score: 5,572 points. Launch price was $750.

Xeon E3-1220 v6

The Xeon E3-1220 v6 is manufactured by Intel. It was released in 28 March 2017 (8 years ago). It is based on the Kaby Lake (2016−2019) architecture. It features 4 cores and 4 threads. Base frequency is 3 GHz, with boost up to 3.5 GHz. L3 cache: 8 MB. L2 cache: 1 MB. Built on 14 nm process technology. Socket: LGA1151. Thermal design power (TDP): 72 Watt. Memory support: DDR4-2400, DDR3L-1866. Passmark benchmark score: 5,589 points. Launch price was $193.

⚡

Processing Power

The Opteron 6376 packs 16 cores / 16 threads, while the Xeon E3-1220 v6 offers 4 cores / 4 threads — the Opteron 6376 has 12 more cores. Boost clocks reach 3.2 GHz on the Opteron 6376 versus 3.5 GHz on the Xeon E3-1220 v6 — a 9% clock advantage for the Xeon E3-1220 v6 (base: 2.3 GHz vs 3 GHz). The Opteron 6376 uses the Abu Dhabi (2012) architecture (32 nm), while the Xeon E3-1220 v6 uses Kaby Lake (2016−2019) (14 nm). In PassMark, the Opteron 6376 scores 5,572 against the Xeon E3-1220 v6's 5,589 — a 0.3% lead for the Xeon E3-1220 v6. L3 cache: 8 MB (total) on the Opteron 6376 vs 8 MB on the Xeon E3-1220 v6.

Feature	Opteron 6376	Xeon E3-1220 v6
Cores / Threads	16 / 16+300%	4 / 4
Boost Clock	3.2 GHz	3.5 GHz+9%
Base Clock	2.3 GHz	3 GHz+30%
L3 Cache	8 MB (total)	8 MB
L2 Cache	16 MB+1500%	1 MB
Process	32 nm	14 nm-56%
Architecture	Abu Dhabi (2012)	Kaby Lake (2016−2019)
PassMark	5,572	5,589

🧠

Memory & Platform

The Opteron 6376 uses the G34 socket (PCIe 2.0), while the Xeon E3-1220 v6 uses LGA1151 (PCIe 3.0) — making them incompatible on the same motherboard.

Feature	Opteron 6376	Xeon E3-1220 v6
Socket	G34	LGA1151
PCIe Generation	PCIe 2.0	PCIe 3.0+50%

💰

Value Analysis

At launch, the Opteron 6376 was priced at $703, while the Xeon E3-1220 v6 came in at $372. On launch pricing ($703 vs $372), Xeon E3-1220 v6 was $331 cheaper. In terms of value on MSRP (PassMark points per dollar), the Opteron 6376 delivers 7.9 pts/$ vs 15.0 pts/$ for the Xeon E3-1220 v6 — making the Xeon E3-1220 v6 the 61.9% better value option.

Feature	Opteron 6376	Xeon E3-1220 v6
MSRP	$703	$372-47%
Performance per Dollar	7.9	15.0+90%
Release Date	2012	2017

Search Opteron 6376 on Amazon

Search Xeon E3-1220 v6 on Amazon

Affiliate Disclosure

ChipVERSUS is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. We may earn a commission on qualifying purchases made through our links. This comes at no additional cost to you and helps support our work in providing comprehensive PC building guides and tools.

Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.