Quadro M5500 vs Radeon RX 6400

NVIDIA

Quadro M5500

2016Core: 1140 MHzBoost: 1165 MHz
VS
AMD

Radeon RX 6400

2022Core: 1923 MHzBoost: 2321 MHz

Quadro M5500 vs Radeon RX 6400 Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro M5500 vs Radeon RX 6400 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro M5500 vs Radeon RX 6400: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro M5500

2016

Why buy it

  • 59.9% more average FPS across 50 tracked games in our benchmark data.
  • 100% more VRAM for high-resolution textures and newer games (8 GB vs 4 GB).

Trade-offs

  • No equivalent frame-generation stack like FSR Frame Generation + AFMF (2023).
  • 2016 hardware with 8 GB of VRAM already sits in legacy territory for modern games.
  • 403.1% HIGHER MSRP
    $800 MSRPvs$159 MSRP
  • Lower G3D Mark per dollar, at 9.9 vs 48.6 G3D/$ ($800 MSRP vs $159 MSRP).
  • 183% higher power demand at 150W vs 53W.

Radeon RX 6400

2022

Why buy it

  • Costs $641 less on MSRP ($159 MSRP vs $800 MSRP).
  • Delivers 391.3% more G3D Mark for each dollar spent, at 48.6 vs 9.9 G3D/$ ($159 MSRP vs $800 MSRP).
  • Access to a newer frame-generation stack with FSR Frame Generation + AFMF (2023).
  • Better long-term bet: RDNA 2.0 (2020−2025) on 6nm gives it a newer hardware base for upcoming games.
  • Draws 53W instead of 150W, a 97W reduction.

Trade-offs

  • Lower average FPS than Quadro M5500 across 50 tracked games in our benchmark data.
  • Less VRAM, with 4 GB vs 8 GB for high-resolution textures and newer games.

Quick Answers

Which GPU is faster for gaming right now?
Quadro M5500 is the faster gaming card right now. In our data, it leads by 59.9% in average FPS across 50 tracked games in our benchmark data and by 2.4% in PassMark G3D (7,915 vs 7,728), so the answer here is pretty clean.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon RX 6400 is the safer long-term pick for 2026 and beyond. The case is simple: the newer feature stack, with FSR 3 (2023) and FSR Frame Generation + AFMF (2023), while Quadro M5500 is limited to no meaningful modern upscaling stack and no comparable frame-generation support, a 6nm process instead of 28nm, 12 vs 0 ray-tracing units, and a newer 2022 generation instead of 2016. That gives it the more rounded hardware package for newer games.
Which GPU is the better buy today?
Radeon RX 6400 makes the most sense to buy today. It is $641 cheaper on MSRP at $159 vs $800, and it leads G3D-per-dollar by 391.3% (48.6 vs 9.9), which is enough to swing the recommendation its way. Quadro M5500 still makes more sense if max raw gaming performance matters more than value.

Quadro M5500 vs Radeon RX 6400 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro M5500

The Quadro M5500 is manufactured by NVIDIA. It was released in April 8 2016. It features the Maxwell 2.0 architecture. The core clock ranges from 1140 MHz to 1165 MHz. It has 2048 shading units. The thermal design power (TDP) is 150W. Manufactured using 28 nm process technology. G3D Mark benchmark score: 7,915 points.

AMD

Radeon RX 6400

The Radeon RX 6400 is manufactured by AMD. It was released in January 19 2022. It features the RDNA 2.0 architecture. The core clock ranges from 1923 MHz to 2321 MHz. It has 768 shading units. The thermal design power (TDP) is 53W. Manufactured using 6 nm process technology. It features 12 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 7,728 points. Launch price was $159.

Graphics Performance

The Quadro M5500 scores 7,915 and the Radeon RX 6400 reaches 7,728 in the G3D Mark benchmark — just a 2.4% difference, making them near-identical in rasterization performance. The Quadro M5500 is built on Maxwell 2.0 while the Radeon RX 6400 uses RDNA 2.0, both on 28 nm vs 6 nm. Shader units: 2,048 (Quadro M5500) vs 768 (Radeon RX 6400). Raw compute: 4.772 TFLOPS (Quadro M5500) vs 3.565 TFLOPS (Radeon RX 6400). Boost clocks: 1165 MHz vs 2321 MHz.

FeatureQuadro M5500Radeon RX 6400
G3D Mark Score
7,915+2%
7,728
Architecture
Maxwell 2.0
RDNA 2.0
Process Node
28 nm
6 nm
Shading Units
2048+167%
768
Compute (TFLOPS)
4.772 TFLOPS+34%
3.565 TFLOPS
Boost Clock
1165 MHz
2321 MHz+99%
ROPs
64+100%
32
TMUs
128+167%
48
L1 Cache
768 KB+200%
256 KB
L2 Cache
2 MB+100%
1 MB

Advanced Features (DLSS/FSR)

The clearest feature edge for the Radeon RX 6400 is support for FSR Frame Generation + AFMF. In games that support it, that can smooth out motion and lift perceived FPS. The Quadro M5500 does not have comparable native support in the same tier.

FeatureQuadro M5500Radeon RX 6400
Upscaling Tech
Upscaling support
FSR 3
Frame Generation
Not Supported
FSR Frame Generation + AFMF
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro M5500 has 8 GB of VRAM, while the Radeon RX 6400 carries 4 GB. Quadro M5500 gives you 100% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bus width is 256-bit on the Quadro M5500 and 64-bit on the Radeon RX 6400. L2 Cache: 2 MB (Quadro M5500) vs 1 MB (Radeon RX 6400) — the Quadro M5500 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro M5500Radeon RX 6400
VRAM Capacity
8 GB+100%
4 GB
Memory Type
GDDR6
GDDR6
Bus Width
256-bit+300%
64-bit
L2 Cache
2 MB+100%
1 MB
🖥️

Display & API Support

DirectX support: 12 (12_1) (Quadro M5500) vs 12.2 (Radeon RX 6400). Vulkan: 1.2 vs 1.3. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 2.

FeatureQuadro M5500Radeon RX 6400
DirectX
12 (12_1)
12.2+2%
Vulkan
1.2
1.3+8%
OpenGL
4.6
4.6
Max Displays
4+100%
2
🎬

Media & Encoding

Hardware encoder: NVENC (Maxwell) (Quadro M5500) vs None (Radeon RX 6400). Decoder: NVDEC (Maxwell) vs VCN 3.0 (Limited). Supported codecs: H.264,H.265,VP9,MPEG-2,VC-1 (Quadro M5500) vs MPEG-2,H.264 (Decode),HEVC (Decode) (Radeon RX 6400).

FeatureQuadro M5500Radeon RX 6400
Encoder
NVENC (Maxwell)
None
Decoder
NVDEC (Maxwell)
VCN 3.0 (Limited)
Codecs
H.264,H.265,VP9,MPEG-2,VC-1
MPEG-2,H.264 (Decode),HEVC (Decode)
🔌

Power & Dimensions

The Quadro M5500 draws 150W versus the Radeon RX 6400's 53W — a 95.6% difference. The Radeon RX 6400 is more power-efficient. Recommended PSU: 350W (Quadro M5500) vs 350W (Radeon RX 6400). Power connectors: PCIe-powered vs None. Card length: 0mm vs 172mm, occupying 0 vs 1 slots. Typical load temperature: 85 vs 75°C.

FeatureQuadro M5500Radeon RX 6400
TDP
150W
53W-65%
Recommended PSU
350W
350W
Power Connector
PCIe-powered
None
Length
0mm
172mm
Height
0mm
112mm
Slots
0-100%
1
Temp (Load)
85
75°C-12%
Perf/Watt
52.8
145.8+176%
💰

Value Analysis

At launch, the Quadro M5500 came in at $800, while the Radeon RX 6400 launched at $159. On MSRP, Radeon RX 6400 was 80.1% cheaper ($641 less). Performance per dollar on MSRP (G3D Mark / MSRP): 9.9 (Quadro M5500) vs 48.6 (Radeon RX 6400) — the Radeon RX 6400 offers 390.9% better value. The newer card here is Radeon RX 6400 (2022 vs 2016).

FeatureQuadro M5500Radeon RX 6400
MSRP
$800
$159-80%
Performance per Dollar
9.9
48.6+391%
Codename
GM204
Navi 24
Release
April 8 2016
January 19 2022
Ranking
#321
#330

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