
Quadro M5500
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Radeon RX 6400
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Performance Spectrum - GPU
About G3D Mark
G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.
Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook
This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.
Quadro M5500
2016Why buy it
- ✅59.9% more average FPS across 50 tracked games in our benchmark data.
- ✅100% more VRAM for high-resolution textures and newer games (8 GB vs 4 GB).
Trade-offs
- ❌No equivalent frame-generation stack like FSR Frame Generation + AFMF (2023).
- ❌Poor future-proofing: 2016-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
- ❌403.1% HIGHER MSRP$800 MSRPvs$159 MSRP
- ❌Lower G3D Mark per dollar, at 9.9 vs 48.6 G3D/$ ($800 MSRP vs $159 MSRP).
- ❌183% higher power demand at 150W vs 53W.
Radeon RX 6400
2022Why buy it
- ✅Costs $641 less on MSRP ($159 MSRP vs $800 MSRP).
- ✅Delivers 391.3% more G3D Mark for each dollar spent, at 48.6 vs 9.9 G3D/$ ($159 MSRP vs $800 MSRP).
- ✅Access to a newer frame-generation stack with FSR Frame Generation + AFMF (2023).
- ✅More future proof: RDNA 2.0 (2020−2025) on 6nm with a newer platform for upcoming games.
- ✅Draws 53W instead of 150W, a 97W reduction.
Trade-offs
- ❌Lower average FPS than Quadro M5500 across 50 tracked games in our benchmark data.
- ❌Less VRAM, with 4 GB vs 8 GB for high-resolution textures and newer games.
Quadro M5500
2016Radeon RX 6400
2022Why buy it
- ✅59.9% more average FPS across 50 tracked games in our benchmark data.
- ✅100% more VRAM for high-resolution textures and newer games (8 GB vs 4 GB).
Why buy it
- ✅Costs $641 less on MSRP ($159 MSRP vs $800 MSRP).
- ✅Delivers 391.3% more G3D Mark for each dollar spent, at 48.6 vs 9.9 G3D/$ ($159 MSRP vs $800 MSRP).
- ✅Access to a newer frame-generation stack with FSR Frame Generation + AFMF (2023).
- ✅More future proof: RDNA 2.0 (2020−2025) on 6nm with a newer platform for upcoming games.
- ✅Draws 53W instead of 150W, a 97W reduction.
Trade-offs
- ❌No equivalent frame-generation stack like FSR Frame Generation + AFMF (2023).
- ❌Poor future-proofing: 2016-era hardware with 8 GB of VRAM is already a legacy-tier option for modern games.
- ❌403.1% HIGHER MSRP$800 MSRPvs$159 MSRP
- ❌Lower G3D Mark per dollar, at 9.9 vs 48.6 G3D/$ ($800 MSRP vs $159 MSRP).
- ❌183% higher power demand at 150W vs 53W.
Trade-offs
- ❌Lower average FPS than Quadro M5500 across 50 tracked games in our benchmark data.
- ❌Less VRAM, with 4 GB vs 8 GB for high-resolution textures and newer games.
Quick Answers
So, is Quadro M5500 better than Radeon RX 6400?
Which one is more future-proof for 2026 and beyond?
Which one is the smarter buy today, not just the cheaper card?
When does Radeon RX 6400 make more sense than Quadro M5500?
Games Benchmarks
Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.
Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2
| Preset | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| 1080p | ||
| low | 108 FPS | 104 FPS |
| medium | 91 FPS | 92 FPS |
| high | 78 FPS | 79 FPS |
| ultra | 52 FPS | 66 FPS |
| 1440p | ||
| low | 92 FPS | 94 FPS |
| medium | 77 FPS | 80 FPS |
| high | 59 FPS | 67 FPS |
| ultra | 38 FPS | 56 FPS |
| 4K | ||
| low | 36 FPS | 45 FPS |
| medium | 33 FPS | 42 FPS |
| high | 21 FPS | 31 FPS |
| ultra | 18 FPS | 28 FPS |

Counter-Strike 2
| Preset | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| 1080p | ||
| low | 229 FPS | 158 FPS |
| medium | 198 FPS | 124 FPS |
| high | 151 FPS | 92 FPS |
| ultra | 120 FPS | 60 FPS |
| 1440p | ||
| low | 170 FPS | 104 FPS |
| medium | 144 FPS | 81 FPS |
| high | 116 FPS | 60 FPS |
| ultra | 91 FPS | 42 FPS |
| 4K | ||
| low | 98 FPS | 53 FPS |
| medium | 82 FPS | 41 FPS |
| high | 69 FPS | 33 FPS |
| ultra | 52 FPS | 20 FPS |

League of Legends
| Preset | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| 1080p | ||
| low | 356 FPS | 329 FPS |
| medium | 285 FPS | 278 FPS |
| high | 237 FPS | 210 FPS |
| ultra | 178 FPS | 172 FPS |
| 1440p | ||
| low | 267 FPS | 232 FPS |
| medium | 214 FPS | 208 FPS |
| high | 178 FPS | 156 FPS |
| ultra | 134 FPS | 121 FPS |
| 4K | ||
| low | 178 FPS | 134 FPS |
| medium | 142 FPS | 121 FPS |
| high | 119 FPS | 82 FPS |
| ultra | 89 FPS | 54 FPS |

Valorant
| Preset | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| 1080p | ||
| low | 234 FPS | 251 FPS |
| medium | 202 FPS | 186 FPS |
| high | 164 FPS | 165 FPS |
| ultra | 140 FPS | 138 FPS |
| 1440p | ||
| low | 183 FPS | 192 FPS |
| medium | 159 FPS | 139 FPS |
| high | 125 FPS | 126 FPS |
| ultra | 104 FPS | 101 FPS |
| 4K | ||
| low | 100 FPS | 101 FPS |
| medium | 80 FPS | 74 FPS |
| high | 63 FPS | 65 FPS |
| ultra | 50 FPS | 50 FPS |
Technical Specifications
Side-by-side comparison of Quadro M5500 and Radeon RX 6400

Quadro M5500
Quadro M5500
The Quadro M5500 is manufactured by NVIDIA. It was released in April 8 2016. It features the Maxwell 2.0 architecture. The core clock ranges from 1140 MHz to 1165 MHz. It has 2048 shading units. The thermal design power (TDP) is 150W. Manufactured using 28 nm process technology. G3D Mark benchmark score: 7,915 points.

Radeon RX 6400
Radeon RX 6400
The Radeon RX 6400 is manufactured by AMD. It was released in January 19 2022. It features the RDNA 2.0 architecture. The core clock ranges from 1923 MHz to 2321 MHz. It has 768 shading units. The thermal design power (TDP) is 53W. Manufactured using 6 nm process technology. It features 12 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 7,728 points. Launch price was $159.
Graphics Performance
The Quadro M5500 scores 7,915 and the Radeon RX 6400 reaches 7,728 in the G3D Mark benchmark — just a 2.4% difference, making them near-identical in rasterization performance. The Quadro M5500 is built on Maxwell 2.0 while the Radeon RX 6400 uses RDNA 2.0, both on 28 nm vs 6 nm. Shader units: 2,048 (Quadro M5500) vs 768 (Radeon RX 6400). Raw compute: 4.772 TFLOPS (Quadro M5500) vs 3.565 TFLOPS (Radeon RX 6400). Boost clocks: 1165 MHz vs 2321 MHz.
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| G3D Mark Score | 7,915+2% | 7,728 |
| Architecture | Maxwell 2.0 | RDNA 2.0 |
| Process Node | 28 nm | 6 nm |
| Shading Units | 2048+167% | 768 |
| Compute (TFLOPS) | 4.772 TFLOPS+34% | 3.565 TFLOPS |
| Boost Clock | 1165 MHz | 2321 MHz+99% |
| ROPs | 64+100% | 32 |
| TMUs | 128+167% | 48 |
| L1 Cache | 768 KB+200% | 256 KB |
| L2 Cache | 2 MB+100% | 1 MB |
Advanced Features (DLSS/FSR)
A critical advantage for the Radeon RX 6400 is support for FSR Frame Generation + AFMF. This allows it to generate entire frames using AI/Algorithms, essentially doubling the frame rate in CPU-bound scenarios or heavy ray-tracing titles. The Quadro M5500 lacks specific hardware/driver support for this native frame generation tier.
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| Upscaling Tech | Upscaling support | FSR 3 |
| Frame Generation | Not Supported | FSR Frame Generation + AFMF |
| Ray Reconstruction | No | No |
| Low Latency | Standard | AMD Anti-Lag |
Video Memory (VRAM)
The Quadro M5500 comes with 8 GB of VRAM, while the Radeon RX 6400 has 4 GB. The Quadro M5500 offers 100% more capacity, crucial for higher resolutions and texture-heavy games. Bus width: 256-bit vs 64-bit. L2 Cache: 2 MB (Quadro M5500) vs 1 MB (Radeon RX 6400) — the Quadro M5500 has significantly larger on-die cache to reduce VRAM reliance.
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| VRAM Capacity | 8 GB+100% | 4 GB |
| Memory Type | GDDR6 | GDDR6 |
| Bus Width | 256-bit+300% | 64-bit |
| L2 Cache | 2 MB+100% | 1 MB |
Display & API Support
DirectX support: 12 (12_1) (Quadro M5500) vs 12.2 (Radeon RX 6400). Vulkan: 1.2 vs 1.3. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 2.
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| DirectX | 12 (12_1) | 12.2+2% |
| Vulkan | 1.2 | 1.3+8% |
| OpenGL | 4.6 | 4.6 |
| Max Displays | 4+100% | 2 |
Media & Encoding
Hardware encoder: NVENC (Maxwell) (Quadro M5500) vs None (Radeon RX 6400). Decoder: NVDEC (Maxwell) vs VCN 3.0 (Limited). Supported codecs: H.264,H.265,VP9,MPEG-2,VC-1 (Quadro M5500) vs MPEG-2,H.264 (Decode),HEVC (Decode) (Radeon RX 6400).
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| Encoder | NVENC (Maxwell) | None |
| Decoder | NVDEC (Maxwell) | VCN 3.0 (Limited) |
| Codecs | H.264,H.265,VP9,MPEG-2,VC-1 | MPEG-2,H.264 (Decode),HEVC (Decode) |
Power & Dimensions
The Quadro M5500 draws 150W versus the Radeon RX 6400's 53W — a 95.6% difference. The Radeon RX 6400 is more power-efficient. Recommended PSU: 350W (Quadro M5500) vs 350W (Radeon RX 6400). Power connectors: PCIe-powered vs None. Card length: 0mm vs 172mm, occupying 0 vs 1 slots. Typical load temperature: 85 vs 75°C.
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| TDP | 150W | 53W-65% |
| Recommended PSU | 350W | 350W |
| Power Connector | PCIe-powered | None |
| Length | 0mm | 172mm |
| Height | 0mm | 112mm |
| Slots | 0-100% | 1 |
| Temp (Load) | 85 | 75°C-12% |
| Perf/Watt | 52.8 | 145.8+176% |
Value Analysis
The Quadro M5500 launched at $800 MSRP, while the Radeon RX 6400 launched at $159. The Radeon RX 6400 costs 80.1% less ($641 savings) on MSRP. Performance per dollar on MSRP (G3D Mark / MSRP): 9.9 (Quadro M5500) vs 48.6 (Radeon RX 6400) — the Radeon RX 6400 offers 390.9% better value. The Radeon RX 6400 is the newer GPU (2022 vs 2016).
| Feature | Quadro M5500 | Radeon RX 6400 |
|---|---|---|
| MSRP | $800 | $159-80% |
| Performance per Dollar | 9.9 | 48.6+391% |
| Codename | GM204 | Navi 24 |
| Release | April 8 2016 | January 19 2022 |
| Ranking | #321 | #330 |
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