EPYC 7351 vs Ryzen 5 PRO 8645HS

AMD

EPYC 7351

16 Cores32 Thrd155 WWMax: 2.9 GHz2017
EPYC family
·······
VS
AMD

Ryzen 5 PRO 8645HS

6 Cores12 Thrd45 WWMax: 5 GHz2024
Similar parts
·······

EPYC 7351 vs Ryzen 5 PRO 8645HS Performance Spectrum

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

EPYC 7351 vs Ryzen 5 PRO 8645HS FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

EPYC 7351 vs Ryzen 5 PRO 8645HS: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

EPYC 7351

2017

Why buy it

  • +300% larger total L3 cache (64 MB vs 16 MB).
  • Better for workstations and heavier parallel workloads: 16 cores / 32 threads.

Trade-offs

  • Worse for gaming: lower average FPS than Ryzen 5 PRO 8645HS across 50 shared CPU benchmark tests.
  • Lower PassMark (23,226 vs 23,227).
  • 244.4% higher power demand at 155W vs 45W.
  • Older platform position on TR4 with DDR4, while Ryzen 5 PRO 8645HS moves to FP7 and DDR5.

Ryzen 5 PRO 8645HS

2024

Why buy it

  • Better for gaming: +15.2% higher average FPS across 50 shared CPU benchmark tests.
  • Draws 45W instead of 155W, a 110W reduction.
  • Newer platform on FP7 with DDR5 support instead of TR4 and DDR4.

Trade-offs

  • Smaller total L3 cache (16 MB vs 64 MB).
  • Less compelling for workstation-style loads than EPYC 7351, which brings 16 cores / 32 threads.

Quick Answers

So, is Ryzen 5 PRO 8645HS better than EPYC 7351?
Not really, because they are built for different jobs. EPYC 7351 makes more sense for workstation-style multi-core throughput, while Ryzen 5 PRO 8645HS is the more practical desktop choice for gaming, platform cost, and everyday use.
Which one is better for gaming?
If gaming is the priority, Ryzen 5 PRO 8645HS is the better pick. According to our tests, it delivers 15.2% more average FPS across 50 shared CPU game tests.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, Ryzen 5 PRO 8645HS is the stronger fit. You are getting 0% better PassMark, backed by 6 cores and 12 threads.
Which one is the smarter buy today, not just the cheaper CPU?
Ryzen 5 PRO 8645HS still makes the most sense overall. Ryzen 5 PRO 8645HS comes in at an unclear MSRP at unclear MSRP versus unclear MSRP, and it still gives you a 15.2% average FPS lead across 50 shared CPU game tests in our data.
Which one is more future-proof for 2026 and beyond?
Ryzen 5 PRO 8645HS makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2024 vs 2017), a healthier platform with FP7 and DDR5 instead of TR4, and more multi-core headroom with 6 cores / 12 threads instead of 16/32. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

EPYC 7351 vs Ryzen 5 PRO 8645HS Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

AMD

EPYC 7351

The EPYC 7351 is manufactured by AMD. It was released in 29 June 2017 (8 years ago). It is based on the Naples (2017−2018) architecture. It features 16 cores and 32 threads. Base frequency is 2.4 GHz, with boost up to 2.9 GHz. L3 cache: 64 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: TR4. Thermal design power (TDP): 170 Watt. Memory support: DDR4 Eight-channel. Passmark benchmark score: 23,226 points. Launch price was $1,100.

AMD

Ryzen 5 PRO 8645HS

The Ryzen 5 PRO 8645HS is manufactured by AMD. It was released in 16 April 2024 (1 year ago). It is based on the Hawk Point (2024−2025) architecture. It features 6 cores and 12 threads. Base frequency is 4.3 GHz, with boost up to 5 GHz. L3 cache: 16 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: FP7. Thermal design power (TDP): 45 Watt. Memory support: DDR5. Passmark benchmark score: 23,227 points. Launch price was $299.

Processing Power

The EPYC 7351 packs 16 cores / 32 threads, while the Ryzen 5 PRO 8645HS offers 6 cores / 12 threads — the EPYC 7351 has 10 more cores. Boost clocks reach 2.9 GHz on the EPYC 7351 versus 5 GHz on the Ryzen 5 PRO 8645HS — a 53.2% clock advantage for the Ryzen 5 PRO 8645HS (base: 2.4 GHz vs 4.3 GHz). The EPYC 7351 uses the Naples (2017−2018) architecture (14 nm), while the Ryzen 5 PRO 8645HS uses Hawk Point (2024−2025) (4 nm). In PassMark, the EPYC 7351 scores 23,226 against the Ryzen 5 PRO 8645HS's 23,227 — a 0% lead for the Ryzen 5 PRO 8645HS. L3 cache: 64 MB (total) on the EPYC 7351 vs 16 MB (total) on the Ryzen 5 PRO 8645HS.

FeatureEPYC 7351Ryzen 5 PRO 8645HS
Cores / Threads
16 / 32+167%
6 / 12
Boost Clock
2.9 GHz
5 GHz+72%
Base Clock
2.4 GHz
4.3 GHz+79%
L3 Cache
64 MB (total)+300%
16 MB (total)
L2 Cache
512K (per core)+51100%
1 MB (per core)
Process
14 nm
4 nm-71%
Architecture
Naples (2017−2018)
Hawk Point (2024−2025)
PassMark
23,226
23,227
🧠

Memory & Platform

The EPYC 7351 uses the TR4 socket (PCIe 4.0), while the Ryzen 5 PRO 8645HS uses FP7 (PCIe 4.0) — making them incompatible on the same motherboard.

FeatureEPYC 7351Ryzen 5 PRO 8645HS
Socket
TR4
FP7
PCIe Generation
PCIe 4.0
PCIe 4.0