EPYC 7543 vs Xeon Platinum 8380
EPYC 7543
Xeon Platinum 8380
Performance Spectrum - CPU
About PassMark
PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.
Value Upgrade Path
This is the official ChipVERSUS Value Rating, comparing raw performance (PassMark) per dollar. Components placed above yours deliver better value for money.
Avg price is the current average price collected from markets across the web.
Performance Per Dollar EPYC 7543
Performance Per Dollar Xeon Platinum 8380
Performance Comparison
About PassMark🏆 Chipversus Verdict
🚀 Performance Leadership
| Insight | EPYC 7543 | Xeon Platinum 8380 |
|---|---|---|
| Gaming | ✅ Superior gaming performance | ❌ Lower gaming performance |
| Workstation | ✅ Better multi-core power | ❌ Weaker in multi-core tasks |
| Price | ✅ More affordable ($468) | ⚠️ Higher cost ($965) |
| Longevity | ✨ Modern (Milan (2021−2023) / 7 nm+) | ✨ Modern (Ice Lake-SP (2021) / 10 nm) |
💎 Value Proposition
| Insight | EPYC 7543 | Xeon Platinum 8380 |
|---|---|---|
| Cost Efficiency | ✅ Better overall value (+108%) | ❌ Lower cost efficiency |
| Upfront Cost | ✅ More affordable ($468) | ⚠️ Higher cost ($965) |
Performance Check
To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.
Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.
Technical Specifications
Side-by-side comparison of EPYC 7543 and Xeon Platinum 8380
EPYC 7543
The EPYC 7543 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,952 points. Launch price was $3,761.
Xeon Platinum 8380
The Xeon Platinum 8380 is manufactured by Intel. It was released in 2021-04-06. It is based on the Ice Lake-SP (2021) architecture. It features 40 cores and 80 threads. Base frequency is 2.3 GHz, with boost up to 3.4 GHz. L3 cache: 60 MB (total). L2 cache: 1 MB (per core). Built on 10 nm process technology. Socket: LGA4189. Thermal design power (TDP): 270 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,318 points. Launch price was $5,846.
Processing Power
The EPYC 7543 packs 32 cores / 64 threads, while the Xeon Platinum 8380 offers 40 cores / 80 threads — the Xeon Platinum 8380 has 8 more cores. Boost clocks reach 3.7 GHz on the EPYC 7543 versus 3.4 GHz on the Xeon Platinum 8380 — a 8.5% clock advantage for the EPYC 7543 (base: 2.8 GHz vs 2.3 GHz). The EPYC 7543 uses the Milan (2021−2023) architecture (7 nm+), while the Xeon Platinum 8380 uses Ice Lake-SP (2021) (10 nm). In PassMark, the EPYC 7543 scores 62,952 against the Xeon Platinum 8380's 62,318 — a 1% lead for the EPYC 7543. L3 cache: 256 MB (total) on the EPYC 7543 vs 60 MB (total) on the Xeon Platinum 8380.
| Feature | EPYC 7543 | Xeon Platinum 8380 |
|---|---|---|
| Cores / Threads | 32 / 64 | 40 / 80+25% |
| Boost Clock | 3.7 GHz+9% | 3.4 GHz |
| Base Clock | 2.8 GHz+22% | 2.3 GHz |
| L3 Cache | 256 MB (total)+327% | 60 MB (total) |
| L2 Cache | 512 kB (per core) | 1 MB (per core)+100% |
| Process | 7 nm+-30% | 10 nm |
| Architecture | Milan (2021−2023) | Ice Lake-SP (2021) |
| PassMark | 62,952+1% | 62,318 |
| Geekbench 6 Single | — | 1,300 |
| Geekbench 6 Multi | — | 40,000 |
Memory & Platform
The EPYC 7543 uses the SP3 socket (PCIe 4.0), while the Xeon Platinum 8380 uses LGA4189 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 3200 on the EPYC 7543 versus DDR4-3200 on the Xeon Platinum 8380 — the EPYC 7543 supports 199.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon Platinum 8380 supports up to 6144 GB of RAM compared to 4096 — 40% more capacity for professional workloads. Both feature 8-channel memory with ECC support. PCIe lanes: 128 (EPYC 7543) vs 64 (Xeon Platinum 8380) — the EPYC 7543 offers 64 more lanes for additional GPUs or NVMe drives. Chipset compatibility: SP3 (EPYC 7543) and C621A (Xeon Platinum 8380).
| Feature | EPYC 7543 | Xeon Platinum 8380 |
|---|---|---|
| Socket | SP3 | LGA4189 |
| PCIe Generation | PCIe 4.0 | PCIe 4.0 |
| Max RAM Speed | 3200+79900% | DDR4-3200 |
| Max RAM Capacity | 4096 | 6144 GB+157286300% |
| RAM Channels | 8 | 8 |
| ECC Support | ✅ | ✅ |
| PCIe Lanes | 128+100% | 64 |
Advanced Features
Neither processor supports overclocking. Only the Xeon Platinum 8380 supports AVX-512 instructions — important for machine learning and scientific applications. Both support VT-x, VT-d virtualization. Primary use case: Xeon Platinum 8380 targets Datacenter. Direct competitor: EPYC 7543 rivals Xeon Platinum 8380; Xeon Platinum 8380 rivals EPYC 7543.
| Feature | EPYC 7543 | Xeon Platinum 8380 |
|---|---|---|
| Integrated GPU | No | No |
| IGPU Model | None | None |
| Unlocked | No | No |
| AVX-512 | No | Yes |
| Virtualization | VT-x, VT-d | VT-x, VT-d |
| Target Use | — | Datacenter |
Value Analysis
The EPYC 7543 launched at $10257 MSRP, while the Xeon Platinum 8380 debuted at $2010. At current prices ($468 vs $965), the EPYC 7543 is $497 cheaper. In terms of value (PassMark points per dollar), the EPYC 7543 delivers 134.5 pts/$ vs 64.6 pts/$ for the Xeon Platinum 8380 — making the EPYC 7543 the 70.3% better value option.
| Feature | EPYC 7543 | Xeon Platinum 8380 |
|---|---|---|
| MSRP | $10257 | $2010-80% |
| Avg Price (30d) | $468-52% | $965 |
| Performance per Dollar | 134.5+108% | 64.6 |
| Release Date | 2021 | 2021 |
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