EPYC 4565P
VS
EPYC 7543

EPYC 4565P vs EPYC 7543

AMD

EPYC 4565P

16 Cores32 Thrd170 WWMax: 5.7 GHz2025
VS
AMD

EPYC 7543

32 Cores64 Thrd225 WWMax: 3.7 GHz2021

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Value Upgrade Path

This is the official ChipVERSUS Value Rating, comparing raw performance (PassMark) per dollar. Components placed above yours deliver better value for money.

MSRP is the manufacturer's suggested retail price.
Avg price is the current average price collected from markets across the web.

Performance Per Dollar EPYC 4565P

#334
Xeon W-2275
MSRP: $1112|Avg: $500
107%
#335
Xeon Gold 6430
MSRP: $2128|Avg: $1850
106%
#336
Xeon Gold 6421N
MSRP: $2368|Avg: $2427
106%
#337
EPYC 7F72
MSRP: $2131|Avg: $2131
106%
#338
Xeon W-2265
MSRP: $1039|Avg: $663
105%
#339
Xeon w7-3555
MSRP: $2749|Avg: $2199
105%
#340
Xeon w7-3445
MSRP: $1989|Avg: $2596
105%
#341
EPYC 9275F
MSRP: $3439|Avg: $3439
105%
#342
Ryzen Threadripper PRO 7975WX
MSRP: $3899|Avg: $3971.7
105%
#343
EPYC 7543P
MSRP: $2730|Avg: $115
104%
#344
EPYC 9455P
MSRP: $4819|Avg: $4366
103%
#345
EPYC 9274F
MSRP: $3060|Avg: $2490
103%
#346
Xeon Gold 6438Y+
MSRP: $2607|Avg: $389
102%
#348
Xeon Gold 6426Y
MSRP: $2145|Avg: N/A
100%
#349
EPYC 4565P
MSRP: $2730|Avg: $1980
100%
#351
Xeon W-2295
MSRP: $1333|Avg: $1400
99%
#352
Xeon 6741P
MSRP: $4421|Avg: $3780
97%
#353
EPYC 7452
MSRP: $2025|Avg: $2025
96%
#354
EPYC 7502P
MSRP: $2300|Avg: $1299
95%
#355
Xeon w7-3455
MSRP: $2489|Avg: $2625
94%
#356
EPYC 9334
MSRP: $2990|Avg: $1810
93%
#357
Xeon w9-3575X
MSRP: $3789|Avg: $675
93%
#358
Xeon w7-3465X
MSRP: $2889|Avg: $468
92%
#359
EPYC 9354
MSRP: $3420|Avg: $2498
92%
#359
Xeon Gold 6530
MSRP: $2128|Avg: $1846
92%
#361
Xeon Silver 4114
MSRP: $612|Avg: $30
91%
#362
EPYC 7532
MSRP: $2380|Avg: $225
91%
#363
Xeon W-2191B
MSRP: $1333|Avg: $39
91%
#364
Xeon Gold 5320
MSRP: $1780|Avg: $1834
90%
Based on actual market prices and performance synthetic scores.

Performance Per Dollar EPYC 7543

#516
Xeon E7-8867 v3
MSRP: $4672|Avg: $4672
129%
#517
Xeon Gold 6150
MSRP: $3358|Avg: $196
128%
#518
Xeon E5-1680 v3
MSRP: $1723|Avg: $200
125%
#519
Xeon E5-2690 v3
MSRP: $2090|Avg: $85
125%
#520
Xeon 6780E
MSRP: $11350|Avg: $8513
124%
#521
Xeon E5-2697A v4
MSRP: $2891|Avg: $121
122%
#522
Xeon Gold 6134
MSRP: $2214|Avg: $378
121%
#523
Xeon Gold 6138T
MSRP: $2742|Avg: $400
121%
#524
Xeon E5-2675 V3
MSRP: $1800|Avg: $100
119%
#524
Xeon E5-2676 V3
MSRP: $1800|Avg: $36
119%
#524
Xeon E7-4880 v2
MSRP: $6619|Avg: $185
119%
#527
Xeon Platinum 8592+
MSRP: $11600|Avg: $11600
118%
#528
Xeon E5-2687W v3
MSRP: $2141|Avg: $749
111%
#529
Xeon Max 9480
MSRP: $12980|Avg: $12980
104%
#530
Xeon E5-2689 v4
MSRP: $2723|Avg: $100
102%
#531
EPYC 7543
MSRP: $10257|Avg: $468
100%
#532
Xeon Platinum 8368Q
MSRP: $7719|Avg: $7719
99%
#533
Xeon Gold 6250
MSRP: $3400|Avg: $2000
98%
#534
Xeon E5-2699 v4
MSRP: $4115|Avg: $400
98%
#535
Xeon W-3245M
MSRP: $5002|Avg: $5002
93%
#536
Xeon W-3265M
MSRP: $6300|Avg: $3500
92%
#537
Xeon Platinum 8180
MSRP: $10009|Avg: $2363
62%
#538
Xeon Platinum 8280M
MSRP: $10009|Avg: $6223
61%
#539
Xeon Platinum 8280
MSRP: $10009|Avg: $2940
60%
#540
Xeon E7-8891 v3
MSRP: $6841|Avg: $418
51%
#541
Xeon E5-4669 v4
MSRP: $7007|Avg: $300
41%
Based on actual market prices and performance synthetic scores.

Performance Comparison

About PassMark

🏆 Chipversus Verdict

🚀 Performance Leadership

Performance Trade-off: The EPYC 7543 leads in gaming performance. However, the EPYC 4565P is the stronger candidate for professional workloads, offering 1.8% greater multi-core processing power.
InsightEPYC 4565PEPYC 7543
Gaming
Lower gaming performance
Superior gaming performance
Workstation
Better multi-core power
Weaker in multi-core tasks
Price
⚠️ Higher cost ($1,980)
More affordable ($468)
Longevity
✨ Modern (Grado (2025) / 4 nm)
✨ Modern (Milan (2021−2023) / 7 nm+)

💎 Value Proposition

Efficiency: The EPYC 7543 leads not only in performance but also in value. It is effectively 76% cheaper ($468 vs $1,980) while identifying as the stronger performer.
InsightEPYC 4565PEPYC 7543
Cost Efficiency
Lower cost efficiency
Better overall value (+316%)
Upfront Cost
⚠️ Higher cost ($1,980)
More affordable ($468)

Performance Check

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Technical Specifications

Side-by-side comparison of EPYC 4565P and EPYC 7543

AMD

EPYC 4565P

The EPYC 4565P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 4.3 GHz, with boost up to 5.7 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 170 Watt. Memory support: DDR5. Passmark benchmark score: 64,068 points. Launch price was $589.

AMD

EPYC 7543

The EPYC 7543 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,952 points. Launch price was $3,761.

Processing Power

The EPYC 4565P packs 16 cores / 32 threads, while the EPYC 7543 offers 32 cores / 64 threads — the EPYC 7543 has 16 more cores. Boost clocks reach 5.7 GHz on the EPYC 4565P versus 3.7 GHz on the EPYC 7543 — a 42.6% clock advantage for the EPYC 4565P (base: 4.3 GHz vs 2.8 GHz). The EPYC 4565P uses the Grado (2025) architecture (4 nm), while the EPYC 7543 uses Milan (2021−2023) (7 nm+). In PassMark, the EPYC 4565P scores 64,068 against the EPYC 7543's 62,952 — a 1.8% lead for the EPYC 4565P. L3 cache: 64 MB (total) on the EPYC 4565P vs 256 MB (total) on the EPYC 7543.

FeatureEPYC 4565PEPYC 7543
Cores / Threads
16 / 32
32 / 64+100%
Boost Clock
5.7 GHz+54%
3.7 GHz
Base Clock
4.3 GHz+54%
2.8 GHz
L3 Cache
64 MB (total)
256 MB (total)+300%
L2 Cache
1 MB (per core)+100%
512 kB (per core)
Process
4 nm-43%
7 nm+
Architecture
Grado (2025)
Milan (2021−2023)
PassMark
64,068+2%
62,952
🧠

Memory & Platform

The EPYC 4565P uses the AM5 socket (PCIe 4.0), while the EPYC 7543 uses SP3 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4565P versus 3200 on the EPYC 7543 — the EPYC 4565P supports 54.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7543 supports up to 4096 of RAM compared to 192 182.1% more capacity for professional workloads. Memory channels: 2 (EPYC 4565P) vs 8 (EPYC 7543). PCIe lanes: 28 (EPYC 4565P) vs 128 (EPYC 7543) — the EPYC 7543 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4565P) and SP3 (EPYC 7543).

FeatureEPYC 4565PEPYC 7543
Socket
AM5
SP3
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
5600+75%
3200
Max RAM Capacity
192
4096+2033%
RAM Channels
2
8+300%
ECC Support
PCIe Lanes
28
128+357%
🔧

Advanced Features

Only the EPYC 4565P has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Only the EPYC 4565P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: VT-x, VT-d, AMD-V (EPYC 4565P) vs VT-x, VT-d (EPYC 7543). The EPYC 4565P includes integrated graphics (AMD Radeon Graphics), while the EPYC 7543 requires a dedicated GPU. Direct competitor: EPYC 4565P rivals Core Ultra 9 285K; EPYC 7543 rivals Xeon Platinum 8380.

FeatureEPYC 4565PEPYC 7543
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
None
Unlocked
Yes
No
AVX-512
Yes
No
Virtualization
VT-x, VT-d, AMD-V
VT-x, VT-d
💰

Value Analysis

The EPYC 4565P launched at $2730 MSRP, while the EPYC 7543 debuted at $10257. At current prices ($1980 vs $468), the EPYC 7543 is $1512 cheaper. In terms of value (PassMark points per dollar), the EPYC 4565P delivers 32.4 pts/$ vs 134.5 pts/$ for the EPYC 7543 — making the EPYC 7543 the 122.4% better value option.

FeatureEPYC 4565PEPYC 7543
MSRP
$2730-73%
$10257
Avg Price (30d)
$1980
$468-76%
Performance per Dollar
32.4
134.5+315%
Release Date
2025
2021