EPYC 4564P
EPYC 7543
EPYC 4564P vs EPYC 7543 Performance Spectrum
About PassMark
PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.
EPYC 4564P vs EPYC 7543 FPS Benchmarks
Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.
Search any supported game below to compare 1080p FPS for both components.
Path of Exile 2
Counter-Strike 2
League of Legends
Valorant
Among Us
Apex Legends
ARC Raiders
Baldur's Gate 3
Call of Duty: Black Ops 6
EPYC 4564P vs EPYC 7543: Pros, Cons & Final Verdict
See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.
EPYC 4564P
2024Why buy it
- ✅Better for gaming: +40.2% higher average FPS across 50 shared CPU benchmark tests.
- ✅Costs $8,740 less on MSRP ($1,517 MSRP vs $10,257 MSRP).
- ✅Delivers 591.5% more PassMark for each dollar spent, at 42.4 vs 6.1 PassMark/$ ($1,517 MSRP vs $10,257 MSRP).
- ✅Draws 170W instead of 225W, a 55W reduction.
- ✅Newer platform on AM5 with DDR5 support instead of SP3 and DDR4.
Trade-offs
- ❌Smaller total L3 cache (64 MB vs 256 MB).
EPYC 7543
2021Why buy it
- ✅+300% larger total L3 cache (256 MB vs 64 MB).
- ✅357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.
Trade-offs
- ❌Worse for gaming: lower average FPS than EPYC 4564P across 50 shared CPU benchmark tests.
- ❌Lower PassMark (62,952 vs 64,387).
- ❌Lower PassMark per dollar, at 6.1 vs 42.4 PassMark/$ ($10,257 MSRP vs $1,517 MSRP).
- ❌32.4% higher power demand at 225W vs 170W.
- ❌Older platform position on SP3 with DDR4, while EPYC 4564P moves to AM5 and DDR5.
Quick Answers
So, is EPYC 4564P better than EPYC 7543?
Which one is better for gaming?
Which one is better for streaming, content creation, and heavy multitasking?
Which one is the smarter buy today, not just the cheaper CPU?
Which one is more future-proof for 2026 and beyond?
EPYC 4564P vs EPYC 7543 Technical Specifications
Side-by-side specs, architecture details, clocks, memory, power, and platform differences.
EPYC 4564P
The EPYC 4564P is manufactured by AMD. It was released in 21 May 2024 (1 year ago). It is based on the Raphael (2023−2025) architecture. It features 16 cores and 32 threads. Base frequency is 4.5 GHz, with boost up to 5.7 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 5 nm process technology. Socket: AM5. Thermal design power (TDP): 170 Watt. Memory support: DDR5. Passmark benchmark score: 64,387 points. Launch price was $699.
EPYC 7543
The EPYC 7543 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,952 points. Launch price was $3,761.
Processing Power
The EPYC 4564P packs 16 cores / 32 threads, while the EPYC 7543 offers 32 cores / 64 threads — the EPYC 7543 has 16 more cores. Boost clocks reach 5.7 GHz on the EPYC 4564P versus 3.7 GHz on the EPYC 7543 — a 42.6% clock advantage for the EPYC 4564P (base: 4.5 GHz vs 2.8 GHz). The EPYC 4564P uses the Raphael (2023−2025) architecture (5 nm), while the EPYC 7543 uses Milan (2021−2023) (7 nm+). In PassMark, the EPYC 4564P scores 64,387 against the EPYC 7543's 62,952 — a 2.3% lead for the EPYC 4564P. L3 cache: 64 MB (total) on the EPYC 4564P vs 256 MB (total) on the EPYC 7543.
| Feature | EPYC 4564P | EPYC 7543 |
|---|---|---|
| Cores / Threads | 16 / 32 | 32 / 64+100% |
| Boost Clock | 5.7 GHz+54% | 3.7 GHz |
| Base Clock | 4.5 GHz+61% | 2.8 GHz |
| L3 Cache | 64 MB (total) | 256 MB (total)+300% |
| L2 Cache | 1 MB (per core)+100% | 512 kB (per core) |
| Process | 5 nm-29% | 7 nm+ |
| Architecture | Raphael (2023−2025) | Milan (2021−2023) |
| PassMark | 64,387+2% | 62,952 |
| Cinebench R23 Multi | 38,500 | — |
| Geekbench 6 Single | 2,975 | — |
| Geekbench 6 Multi | 18,581 | — |
Memory & Platform
The EPYC 4564P uses the AM5 socket (PCIe 4.0), while the EPYC 7543 uses SP3 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches DDR5-5200 on the EPYC 4564P versus 3200 on the EPYC 7543 — the EPYC 4564P supports 62.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7543 supports up to 4096 GB of RAM compared to 192 GB — 2033.3% more capacity for professional workloads. Memory channels: 2 (EPYC 4564P) vs 8 (EPYC 7543). PCIe lanes: 28 (EPYC 4564P) vs 128 (EPYC 7543) — the EPYC 7543 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: X670E,X670,B650E,B650 (EPYC 4564P) and SP3 (EPYC 7543).
| Feature | EPYC 4564P | EPYC 7543 |
|---|---|---|
| Socket | AM5 | SP3 |
| PCIe Generation | PCIe 4.0 | PCIe 4.0 |
| Max RAM Speed | DDR5-5200+63% | 3200 |
| Max RAM Capacity | 192 GB | 4096 GB+2033% |
| RAM Channels | 2 | 8+300% |
| ECC Support | Yes | Yes |
| PCIe Lanes | 28 | 128+357% |
Advanced Features
Neither processor supports overclocking. Only the EPYC 4564P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: AMD-V, AMD-Vi (EPYC 4564P) vs VT-x, VT-d (EPYC 7543). The EPYC 4564P includes integrated graphics (Radeon Graphics), while the EPYC 7543 requires a dedicated GPU. Primary use case: EPYC 4564P targets High-end Server / Workstation. Direct competitor: EPYC 4564P rivals Ryzen 9 7950X; EPYC 7543 rivals Xeon Platinum 8380.
| Feature | EPYC 4564P | EPYC 7543 |
|---|---|---|
| Integrated GPU | Yes | No |
| IGPU Model | Radeon Graphics | None |
| Unlocked | No | No |
| AVX-512 | Yes | No |
| Virtualization | AMD-V, AMD-Vi | VT-x, VT-d |
| Target Use | High-end Server / Workstation | — |
Value Analysis
At launch, the EPYC 4564P was priced at $1517, while the EPYC 7543 came in at $10257. On launch pricing ($1517 vs $10257), EPYC 4564P was $8740 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4564P delivers 42.4 pts/$ vs 6.1 pts/$ for the EPYC 7543 — making the EPYC 4564P the 149.5% better value option.
| Feature | EPYC 4564P | EPYC 7543 |
|---|---|---|
| MSRP | $1517-85% | $10257 |
| Performance per Dollar | 42.4+595% | 6.1 |
| Release Date | 2024 | 2021 |
Affiliate Disclosure
ChipVERSUS is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. We may earn a commission on qualifying purchases made through our links. This comes at no additional cost to you and helps support our work in providing comprehensive PC building guides and tools.
Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.
Top Performing CPUs
The most powerful cpus ranked by PassMark CPU Mark benchmark scores.
You May Also Compare
Similar CPU comparisons based on EPYC 4564P and EPYC 7543
