EPYC 4564P vs EPYC 7543P

AMD

EPYC 4564P

16 Cores32 Thrd170 WWMax: 5.7 GHz2024
EPYC family
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VS
AMD

EPYC 7543P

32 Cores64 Thrd225 WWMax: 3.7 GHz2021
EPYC family
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EPYC 4564P vs EPYC 7543P Performance Spectrum

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

EPYC 4564P vs EPYC 7543P FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

EPYC 4564P vs EPYC 7543P: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

EPYC 4564P

2024

Why buy it

  • Better for gaming: +40.2% higher average FPS across 50 shared CPU benchmark tests.
  • Costs $1,213 less on MSRP ($1,517 MSRP vs $2,730 MSRP).
  • Delivers 74.0% more PassMark for each dollar spent, at 42.4 vs 24.4 PassMark/$ ($1,517 MSRP vs $2,730 MSRP).
  • Draws 170W instead of 225W, a 55W reduction.
  • Newer platform on AM5 with DDR5 support instead of SP3 and DDR4.

Trade-offs

  • Lower PassMark (64,387 vs 66,590).
  • Smaller total L3 cache (64 MB vs 256 MB).

EPYC 7543P

2021

Why buy it

  • +3.4% higher PassMark.
  • +300% larger total L3 cache (256 MB vs 64 MB).
  • 357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4564P across 50 shared CPU benchmark tests.
  • Lower PassMark per dollar, at 24.4 vs 42.4 PassMark/$ ($2,730 MSRP vs $1,517 MSRP).
  • 32.4% higher power demand at 225W vs 170W.
  • Older platform position on SP3 with DDR4, while EPYC 4564P moves to AM5 and DDR5.
  • No integrated graphics, while EPYC 4564P can still boot and troubleshoot without a discrete GPU.

Quick Answers

So, is EPYC 4564P better than EPYC 7543P?
It depends on what you want from the system. For gaming, EPYC 4564P is ahead with a 40.2% average FPS lead across 50 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, EPYC 7543P pulls ahead with 3.4% better PassMark. EPYC 7543P also has the bigger cache pool with 300% larger total L3 cache (256 MB vs 64 MB).
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 7543P is the stronger fit. You are getting 3.4% better PassMark, backed by 32 cores and 64 threads. It also has the larger cache pool with 300% larger total L3 cache (256 MB vs 64 MB).
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4564P is the better buy right now. EPYC 4564P comes in $1,213 cheaper on MSRP at $1,517 MSRP versus $2,730 MSRP, and it still gives you a 40.2% average FPS lead across 50 shared CPU game tests in our data. The compromise is that EPYC 7543P is still stronger for heavier multi-core work with 3.4% better PassMark. It is also 74.0% better value on MSRP (42.4 vs 24.4 PassMark/$), so you are getting the faster CPU without taking a value hit on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4564P makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2024 vs 2021), a healthier platform with AM5 and DDR5 instead of SP3, and AVX-512 support for heavier modern compute workloads. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

EPYC 4564P vs EPYC 7543P Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

AMD

EPYC 4564P

The EPYC 4564P is manufactured by AMD. It was released in 21 May 2024 (1 year ago). It is based on the Raphael (2023−2025) architecture. It features 16 cores and 32 threads. Base frequency is 4.5 GHz, with boost up to 5.7 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 5 nm process technology. Socket: AM5. Thermal design power (TDP): 170 Watt. Memory support: DDR5. Passmark benchmark score: 64,387 points. Launch price was $699.

AMD

EPYC 7543P

The EPYC 7543P is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 66,590 points. Launch price was $2,730.

Processing Power

The EPYC 4564P packs 16 cores / 32 threads, while the EPYC 7543P offers 32 cores / 64 threads — the EPYC 7543P has 16 more cores. Boost clocks reach 5.7 GHz on the EPYC 4564P versus 3.7 GHz on the EPYC 7543P — a 42.6% clock advantage for the EPYC 4564P (base: 4.5 GHz vs 2.8 GHz). The EPYC 4564P uses the Raphael (2023−2025) architecture (5 nm), while the EPYC 7543P uses Milan (2021−2023) (7 nm+). In PassMark, the EPYC 4564P scores 64,387 against the EPYC 7543P's 66,590 — a 3.4% lead for the EPYC 7543P. L3 cache: 64 MB (total) on the EPYC 4564P vs 256 MB (total) on the EPYC 7543P.

FeatureEPYC 4564PEPYC 7543P
Cores / Threads
16 / 32
32 / 64+100%
Boost Clock
5.7 GHz+54%
3.7 GHz
Base Clock
4.5 GHz+61%
2.8 GHz
L3 Cache
64 MB (total)
256 MB (total)+300%
L2 Cache
1 MB (per core)+100%
512 kB (per core)
Process
5 nm-29%
7 nm+
Architecture
Raphael (2023−2025)
Milan (2021−2023)
PassMark
64,387
66,590+3%
Cinebench R23 Multi
38,500
Geekbench 6 Single
2,975
Geekbench 6 Multi
18,581
🧠

Memory & Platform

The EPYC 4564P uses the AM5 socket (PCIe 4.0), while the EPYC 7543P uses SP3 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches DDR5-5200 on the EPYC 4564P versus 3200 on the EPYC 7543P — the EPYC 4564P supports 62.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7543P supports up to 4096 GB of RAM compared to 192 GB 2033.3% more capacity for professional workloads. Memory channels: 2 (EPYC 4564P) vs 8 (EPYC 7543P). PCIe lanes: 28 (EPYC 4564P) vs 128 (EPYC 7543P) — the EPYC 7543P offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: X670E,X670,B650E,B650 (EPYC 4564P) and SP3 (EPYC 7543P).

FeatureEPYC 4564PEPYC 7543P
Socket
AM5
SP3
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
DDR5-5200+63%
3200
Max RAM Capacity
192 GB
4096 GB+2033%
RAM Channels
2
8+300%
ECC Support
Yes
Yes
PCIe Lanes
28
128+357%
🔧

Advanced Features

Neither processor supports overclocking. Only the EPYC 4564P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: AMD-V, AMD-Vi (EPYC 4564P) vs VT-x, VT-d (EPYC 7543P). The EPYC 4564P includes integrated graphics (Radeon Graphics), while the EPYC 7543P requires a dedicated GPU. Primary use case: EPYC 4564P targets High-end Server / Workstation. Direct competitor: EPYC 4564P rivals Ryzen 9 7950X; EPYC 7543P rivals Xeon Platinum 8380.

FeatureEPYC 4564PEPYC 7543P
Integrated GPU
Yes
No
IGPU Model
Radeon Graphics
None
Unlocked
No
No
AVX-512
Yes
No
Virtualization
AMD-V, AMD-Vi
VT-x, VT-d
Target Use
High-end Server / Workstation
💰

Value Analysis

At launch, the EPYC 4564P was priced at $1517, while the EPYC 7543P came in at $2730. On launch pricing ($1517 vs $2730), EPYC 4564P was $1213 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4564P delivers 42.4 pts/$ vs 24.4 pts/$ for the EPYC 7543P — making the EPYC 4564P the 54% better value option.

FeatureEPYC 4564PEPYC 7543P
MSRP
$1517-44%
$2730
Performance per Dollar
42.4+74%
24.4
Release Date
2024
2021

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