Opteron 4376 HE vs Xeon E5-1603 v4

Opteron 4376 HE vs Xeon E5-1603 v4 Performance Spectrum

Opteron 4376 HE

8 / 8

4,318

0.0%

Ryzen Threadripper PRO 7965WX

Xeon E5-1603 v4

4 / 4

4,355

+0.9%

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Opteron 4376 HE vs Xeon E5-1603 v4 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Opteron 4376 HE vs Xeon E5-1603 v4: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Opteron 4376 HE

2012

Why buy it

✅Draws 65W instead of 140W, a 75W reduction.

Trade-offs

❌Lower PassMark (4,318 vs 4,355).

Xeon E5-1603 v4

2016

Why buy it

Trade-offs

❌115.4% higher power demand at 140W vs 65W.

Quick Answers

So, is Xeon E5-1603 v4 better than Opteron 4376 HE?

Yes. Xeon E5-1603 v4 is the better all-around CPU here. It gives you a 2.6% average FPS lead across 7 shared CPU game tests in our data, 0.9% better PassMark, and the stronger long-term platform, which is enough to make it the stronger overall pick.

Which one is better for gaming?

If gaming is the priority, Xeon E5-1603 v4 is the better pick. According to our tests, it delivers 2.6% more average FPS across 7 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon E5-1603 v4 is the stronger fit. You are getting 0.9% better PassMark.

Which one is the smarter buy today, not just the cheaper CPU?

Xeon E5-1603 v4 still makes the most sense overall. Xeon E5-1603 v4 comes in at an unclear MSRP at unclear MSRP versus unclear MSRP, and it still gives you a 2.6% average FPS lead across 7 shared CPU game tests in our data.

Which one is more future-proof for 2026 and beyond?

Xeon E5-1603 v4 makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2016 vs 2012). That extra compute headroom is more likely to matter as games, background tasks, and creator workloads get heavier.

Opteron 4376 HE vs Xeon E5-1603 v4 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Opteron 4376 HE

The Opteron 4376 HE is manufactured by AMD. It was released in 2015-01-01. It is based on the Seoul (2012) architecture. It features 8 cores and 8 threads. Base frequency is 2.6 GHz, with boost up to 3.6 GHz. L3 cache: 8192 kB (total). L2 cache: 8192 kB. Built on 32 nm process technology. Socket: C32. Thermal design power (TDP): 65 Watt. Memory support: DDR3. Passmark benchmark score: 4,318 points. Launch price was $800.

Xeon E5-1603 v4

The Xeon E5-1603 v4 is manufactured by Intel. It was released in 2015-01-01. Passmark benchmark score: 4,355 points. Launch price was $800.

⚡

Processing Power

The Opteron 4376 HE is built on the Seoul (2012) architecture. In PassMark, the Opteron 4376 HE scores 4,318 against the Xeon E5-1603 v4's 4,355 — a 0.9% lead for the Xeon E5-1603 v4.

Feature	Opteron 4376 HE	Xeon E5-1603 v4
Cores / Threads	8 / 8	—
Boost Clock	3.6 GHz	—
Base Clock	2.6 GHz	—
L3 Cache	8192 kB (total)	—
L2 Cache	8192 kB	—
Process	32 nm	—
Architecture	Seoul (2012)	—
PassMark	4,318	4,355