Opteron 6378 vs Ryzen 3 PRO 3300U

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Opteron 6378 vs Ryzen 3 PRO 3300U FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Opteron 6378 vs Ryzen 3 PRO 3300U: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Opteron 6378

2012

Why buy it

✅Better for gaming: +20.5% higher average FPS across 50 shared CPU benchmark tests.
✅+100% larger total L3 cache (8 MB vs 4 MB).
✅Better for workstations and heavier parallel workloads: 16 cores / 16 threads.

Trade-offs

❌666.7% higher power demand at 115W vs 15W.

Ryzen 3 PRO 3300U

2019

Why buy it

✅Draws 15W instead of 115W, a 100W reduction.

Trade-offs

❌Worse for gaming: lower average FPS than Opteron 6378 across 50 shared CPU benchmark tests.
❌Lower PassMark (5,831 vs 5,889).
❌Smaller total L3 cache (4 MB vs 8 MB).
❌Less compelling for workstation-style loads than Opteron 6378, which brings 16 cores / 16 threads.

Quick Answers

So, is Opteron 6378 better than Ryzen 3 PRO 3300U?

Not really, because they are built for different jobs. Opteron 6378 makes more sense for workstation-style multi-core throughput, while Ryzen 3 PRO 3300U is the more practical desktop choice for gaming, platform cost, and everyday use.

Which one is better for gaming?

If gaming is the priority, Opteron 6378 is the better pick. According to our tests, it delivers 20.5% more average FPS across 50 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Opteron 6378 is the stronger fit. You are getting 1% better PassMark, backed by 16 cores and 16 threads. It also has the larger cache pool with 100% larger total L3 cache (8 MB vs 4 MB).

Which one is the smarter buy today, not just the cheaper CPU?

Opteron 6378 still makes the most sense overall. Opteron 6378 comes in at an unclear MSRP at unclear MSRP versus unclear MSRP, and it still gives you a 20.5% average FPS lead across 50 shared CPU game tests in our data.

Which one is more future-proof for 2026 and beyond?

Ryzen 3 PRO 3300U makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2019 vs 2012). That makes it the safer long-term bet.

Opteron 6378 vs Ryzen 3 PRO 3300U Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Opteron 6378

The Opteron 6378 is manufactured by AMD. It was released in 5 November 2012 (13 years ago). It is based on the Abu Dhabi (2012) architecture. It features 16 cores and 16 threads. Base frequency is 2.4 GHz, with boost up to 3.3 GHz. L3 cache: 8 MB (total). L2 cache: 16 MB. Built on 32 nm process technology. Socket: G34. Thermal design power (TDP): 115 Watt. Memory support: DDR3. Passmark benchmark score: 5,889 points. Launch price was $396.

Ryzen 3 PRO 3300U

The Ryzen 3 PRO 3300U is manufactured by AMD. It was released in 8 April 2019 (6 years ago). It is based on the Picasso (2019−2022) architecture. It features 4 cores and 4 threads. Base frequency is 2.1 GHz, with boost up to 3.5 GHz. L3 cache: 4 MB (total). L2 cache: 512K (per core). Built on 12 nm process technology. Socket: FP5. Thermal design power (TDP): 15 Watt. Memory support: DDR4 Dual-channel. Passmark benchmark score: 5,831 points. Launch price was $149.

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Processing Power

The Opteron 6378 packs 16 cores / 16 threads, while the Ryzen 3 PRO 3300U offers 4 cores / 4 threads — the Opteron 6378 has 12 more cores. Boost clocks reach 3.3 GHz on the Opteron 6378 versus 3.5 GHz on the Ryzen 3 PRO 3300U — a 5.9% clock advantage for the Ryzen 3 PRO 3300U (base: 2.4 GHz vs 2.1 GHz). The Opteron 6378 uses the Abu Dhabi (2012) architecture (32 nm), while the Ryzen 3 PRO 3300U uses Picasso (2019−2022) (12 nm). In PassMark, the Opteron 6378 scores 5,889 against the Ryzen 3 PRO 3300U's 5,831 — a 1% lead for the Opteron 6378. L3 cache: 8 MB (total) on the Opteron 6378 vs 4 MB (total) on the Ryzen 3 PRO 3300U.

Feature	Opteron 6378	Ryzen 3 PRO 3300U
Cores / Threads	16 / 16+300%	4 / 4
Boost Clock	3.3 GHz	3.5 GHz+6%
Base Clock	2.4 GHz+14%	2.1 GHz
L3 Cache	8 MB (total)+100%	4 MB (total)
L2 Cache	16 MB	512K (per core)+3100%
Process	32 nm	12 nm-63%
Architecture	Abu Dhabi (2012)	Picasso (2019−2022)
PassMark	5,889	5,831

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Memory & Platform

The Opteron 6378 uses the G34 socket (PCIe 2.0), while the Ryzen 3 PRO 3300U uses FP5 (PCIe 3.0) — making them incompatible on the same motherboard.