Opteron 6378 vs Xeon E-2104G

Opteron 6378 vs Xeon E-2104G Performance Spectrum

Opteron 6378

16 / 16

5,889

+0.5%

Ryzen Threadripper PRO 3975WX

Ryzen Threadripper PRO 7965WX

Xeon E-2104G

4 / 4

5,858

0.0%

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Opteron 6378 vs Xeon E-2104G FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Opteron 6378 vs Xeon E-2104G: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Opteron 6378

2012

Why buy it

✅Better for gaming: +26.2% higher average FPS across 50 shared CPU benchmark tests.

Trade-offs

❌76.9% higher power demand at 115W vs 65W.

Xeon E-2104G

2018

Why buy it

✅Draws 65W instead of 115W, a 50W reduction.

Trade-offs

❌Worse for gaming: lower average FPS than Opteron 6378 across 50 shared CPU benchmark tests.
❌Lower PassMark (5,858 vs 5,889).
❌Launch MSRP is still $193 MSRP, while Opteron 6378 mostly shows up through inconsistent older-market listings.

Quick Answers

So, is Opteron 6378 better than Xeon E-2104G?

Yes. Opteron 6378 is the better all-around CPU here. It gives you a 26.2% average FPS lead across 50 shared CPU game tests in our data and 0.5% better PassMark, which is enough to make it the stronger overall pick.

Which one is better for gaming?

If gaming is the priority, Opteron 6378 is the better pick. According to our tests, it delivers 26.2% more average FPS across 50 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Opteron 6378 is the stronger fit. You are getting 0.5% better PassMark, backed by 16 cores and 16 threads.

Which one is the smarter buy today, not just the cheaper CPU?

Opteron 6378 is still the faster CPU overall, but Xeon E-2104G is easier to justify if budget matters more than peak performance. Opteron 6378 comes in at an unclear MSRP at unclear MSRP versus $193 MSRP, and it still gives you a 26.2% average FPS lead across 50 shared CPU game tests in our data. Xeon E-2104G is also 100.0% better value on MSRP (30.4 vs 0.0 PassMark/$), which is why it can still make sense for tighter-budget builds on paper.

Which one is more future-proof for 2026 and beyond?

Xeon E-2104G makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2018 vs 2012). That makes it the safer long-term bet.

Opteron 6378 vs Xeon E-2104G Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Opteron 6378

The Opteron 6378 is manufactured by AMD. It was released in 5 November 2012 (13 years ago). It is based on the Abu Dhabi (2012) architecture. It features 16 cores and 16 threads. Base frequency is 2.4 GHz, with boost up to 3.3 GHz. L3 cache: 8 MB (total). L2 cache: 16 MB. Built on 32 nm process technology. Socket: G34. Thermal design power (TDP): 115 Watt. Memory support: DDR3. Passmark benchmark score: 5,889 points. Launch price was $396.

Xeon E-2104G

The Xeon E-2104G is manufactured by Intel. It was released in 12 July 2018 (7 years ago). It is based on the Coffee Lake-S WS (2018−2019) architecture. It features 4 cores and 4 threads. Base frequency is 3.2 GHz, with boost up to 3.2 GHz. L3 cache: 8 MB (total). L2 cache: 256 kB (per core). Built on 14 nm process technology. Socket: LGA1151. Thermal design power (TDP): 65 Watt. Memory support: DDR4-2666. Passmark benchmark score: 5,858 points. Launch price was $193.

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Processing Power

The Opteron 6378 packs 16 cores / 16 threads, while the Xeon E-2104G offers 4 cores / 4 threads — the Opteron 6378 has 12 more cores. Boost clocks reach 3.3 GHz on the Opteron 6378 versus 3.2 GHz on the Xeon E-2104G — a 3.1% clock advantage for the Opteron 6378 (base: 2.4 GHz vs 3.2 GHz). The Opteron 6378 uses the Abu Dhabi (2012) architecture (32 nm), while the Xeon E-2104G uses Coffee Lake-S WS (2018−2019) (14 nm). In PassMark, the Opteron 6378 scores 5,889 against the Xeon E-2104G's 5,858 — a 0.5% lead for the Opteron 6378. Both processors carry 8 MB (total) of L3 cache.

Feature	Opteron 6378	Xeon E-2104G
Cores / Threads	16 / 16+300%	4 / 4
Boost Clock	3.3 GHz+3%	3.2 GHz
Base Clock	2.4 GHz	3.2 GHz+33%
L3 Cache	8 MB (total)	8 MB (total)
L2 Cache	16 MB+6300%	256 kB (per core)
Process	32 nm	14 nm-56%
Architecture	Abu Dhabi (2012)	Coffee Lake-S WS (2018−2019)
PassMark	5,889	5,858

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Memory & Platform

The Opteron 6378 uses the G34 socket (PCIe 2.0), while the Xeon E-2104G uses LGA1151 (PCIe 3.0) — making them incompatible on the same motherboard.