Xeon E-2378 vs Xeon E5-2680 v4

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Xeon E-2378 vs Xeon E5-2680 v4 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Xeon E-2378 vs Xeon E5-2680 v4: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Xeon E-2378

2021

Why buy it

✅Better for gaming: +14.3% higher average FPS across 50 shared CPU benchmark tests.
✅Draws 65W instead of 120W, a 55W reduction.
✅AVX-512 support for select workstation, AI, and scientific workloads.

Trade-offs

❌Lower PassMark (17,069 vs 17,292).
❌Smaller total L3 cache (16 MB vs 35 MB).
❌Launch MSRP is still $362 MSRP, while Xeon E5-2680 v4 mostly shows up through inconsistent older-market listings.

Xeon E5-2680 v4

2016

Why buy it

✅+1.3% higher PassMark.
✅+118.8% larger total L3 cache (35 MB vs 16 MB).
✅100% more PCIe lanes (40 vs 20) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than Xeon E-2378 across 50 shared CPU benchmark tests.
❌84.6% higher power demand at 120W vs 65W.
❌No AVX-512 support for niche heavy compute workloads where it can matter.

Quick Answers

So, is Xeon E-2378 better than Xeon E5-2680 v4?

It depends on what you want from the system. For gaming, Xeon E-2378 is ahead with a 14.3% average FPS lead across 50 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, Xeon E5-2680 v4 pulls ahead with 1.3% better PassMark. Xeon E5-2680 v4 also has the bigger cache pool with 118.8% larger total L3 cache (35 MB vs 16 MB).

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, Xeon E5-2680 v4 is the stronger fit. You are getting 1.3% better PassMark, backed by 14 cores and 28 threads. It also has the larger cache pool with 118.8% larger total L3 cache (35 MB vs 16 MB).

Which one is the smarter buy today, not just the cheaper CPU?

Xeon E-2378 is the better buy right now. Xeon E-2378 comes in at an unclear MSRP at $362 MSRP versus unclear MSRP, and it still gives you a 14.3% average FPS lead across 50 shared CPU game tests in our data. The compromise is that Xeon E5-2680 v4 is still stronger for heavier multi-core work with 1.3% better PassMark. It is also 100.0% better value on MSRP (47.2 vs 0.0 PassMark/$), so you are getting the faster CPU without taking a value hit on paper.

Which one is more future-proof for 2026 and beyond?

Xeon E-2378 makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2021 vs 2016) and AVX-512 support for heavier modern compute workloads. That makes it the safer long-term bet.

Xeon E-2378 vs Xeon E5-2680 v4 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Xeon E-2378

The Xeon E-2378 is manufactured by Intel. It was released in 2015-01-01. It is based on the Rocket Lake-E (2021) architecture. It features 8 cores and 16 threads. Base frequency is 2.6 GHz, with boost up to 4.8 GHz. L3 cache: 16 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: LGA1200. Thermal design power (TDP): 65 Watt. Memory support: DDR4-3200. Passmark benchmark score: 17,069 points. Launch price was $800.

Xeon E5-2680 v4

The Xeon E5-2680 v4 is manufactured by Intel. It was released in 20 June 2016 (9 years ago). It is based on the Broadwell-EP (2016) architecture. It features 14 cores and 28 threads. Base frequency is 2.4 GHz, with boost up to 3.3 GHz. L3 cache: 35 MB. L2 cache: 3.5 MB. Built on 14 nm process technology. Socket: LGA2011. Thermal design power (TDP): 120 Watt. Memory support: DDR4-1600, DDR4-1866, DDR4-2133, DDR4-2400. Passmark benchmark score: 17,292 points. Launch price was $1,745.

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Processing Power

The Xeon E-2378 packs 8 cores / 16 threads, while the Xeon E5-2680 v4 offers 14 cores / 28 threads — the Xeon E5-2680 v4 has 6 more cores. Boost clocks reach 4.8 GHz on the Xeon E-2378 versus 3.3 GHz on the Xeon E5-2680 v4 — a 37% clock advantage for the Xeon E-2378 (base: 2.6 GHz vs 2.4 GHz). The Xeon E-2378 uses the Rocket Lake-E (2021) architecture (14 nm), while the Xeon E5-2680 v4 uses Broadwell-EP (2016) (14 nm). In PassMark, the Xeon E-2378 scores 17,069 against the Xeon E5-2680 v4's 17,292 — a 1.3% lead for the Xeon E5-2680 v4. L3 cache: 16 MB (total) on the Xeon E-2378 vs 35 MB on the Xeon E5-2680 v4.

Feature	Xeon E-2378	Xeon E5-2680 v4
Cores / Threads	8 / 16	14 / 28+75%
Boost Clock	4.8 GHz+45%	3.3 GHz
Base Clock	2.6 GHz+8%	2.4 GHz
L3 Cache	16 MB (total)	35 MB+119%
L2 Cache	512K (per core)+14529%	3.5 MB
Process	14 nm	14 nm
Architecture	Rocket Lake-E (2021)	Broadwell-EP (2016)
PassMark	17,069	17,292+1%
Geekbench 6 Single	1,821	—
Geekbench 6 Multi	9,986	—

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Memory & Platform

The Xeon E-2378 uses the LGA1200 socket (PCIe 4.0), while the Xeon E5-2680 v4 uses LGA2011 (PCIe 3.0) — making them incompatible on the same motherboard. Maximum memory speed reaches DDR4-3200 on the Xeon E-2378 versus 2400 on the Xeon E5-2680 v4 — the Xeon E-2378 supports 33.3% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon E5-2680 v4 supports up to 1536 GB of RAM compared to 128 GB — 1100% more capacity for professional workloads. Memory channels: 2 (Xeon E-2378) vs 4 (Xeon E5-2680 v4). PCIe lanes: 20 (Xeon E-2378) vs 40 (Xeon E5-2680 v4) — the Xeon E5-2680 v4 offers 20 more lanes for additional GPUs or NVMe drives. Chipset compatibility: C252,C256 (Xeon E-2378) and C612 (Xeon E5-2680 v4).

Feature	Xeon E-2378	Xeon E5-2680 v4
Socket	LGA1200	LGA2011
PCIe Generation	PCIe 4.0+33%	PCIe 3.0
Max RAM Speed	DDR4-3200+33%	2400
Max RAM Capacity	128 GB	1536 GB+1100%
RAM Channels	2	4+100%
ECC Support	Yes	Yes
PCIe Lanes	20	40+100%

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Advanced Features

Only the Xeon E-2378 supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: Yes (Xeon E-2378) vs VT-x, VT-d (Xeon E5-2680 v4). Direct competitor: Xeon E5-2680 v4 rivals Xeon Silver 4114.