Quadro P5000 vs Radeon RX 6600S

CPU

GPU

Quadro P5000

2016Core: 1607 MHzBoost: 1733 MHz

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Radeon RX 6600S

2022Core: 1700 MHzBoost: 2000 MHz

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Quadro P5000 vs Radeon RX 6600S Performance Spectrum

Quadro P5000

16 GB 180

12,728

0.0%

GeForce GTX 1650 (móvel)

GeForce GTX Titan

GeForce GTX 1070 with Max-Q Design

GeForce RTX 3050 A Mobile

GeForce RTX 2070

GeForce RTX 2080 SUPER

GeForce RTX 4060 Ti 16GB

GeForce GTX 1080 SLI (móvel)

Radeon RX 6600S

4 GB 80

13,016

+2.3%

Radeon RX 470 (móvel)

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro P5000 vs Radeon RX 6600S FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro P5000 vs Radeon RX 6600S: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro P5000

2016

Why buy it

✅27.8% more average FPS across 50 tracked games in our benchmark data.
✅300% more VRAM for high-resolution textures and newer games (16 GB vs 4 GB).

Trade-offs

❌No equivalent frame-generation stack like FSR Frame Generation + AFMF (2023).
❌2016 hardware with 16 GB of VRAM already sits in legacy territory for modern games.
❌
524.8% HIGHER MSRP
$2,499 MSRPvs$400 MSRP
❌Lower G3D Mark per dollar, at 5.1 vs 32.5 G3D/$ ($2,499 MSRP vs $400 MSRP).
❌125% higher power demand at 180W vs 80W.

Radeon RX 6600S

2022

Why buy it

✅Costs $2,099 less on MSRP ($400 MSRP vs $2,499 MSRP).
✅Delivers 538.9% more G3D Mark for each dollar spent, at 32.5 vs 5.1 G3D/$ ($400 MSRP vs $2,499 MSRP).
✅Access to a newer frame-generation stack with FSR Frame Generation + AFMF (2023).
✅Better long-term bet: RDNA 2.0 (2020−2025) on 7nm gives it a newer hardware base for upcoming games.
✅Draws 80W instead of 180W, a 100W reduction.

Trade-offs

❌Lower average FPS than Quadro P5000 across 50 tracked games in our benchmark data.
❌Less VRAM, with 4 GB vs 16 GB for high-resolution textures and newer games.

Quick Answers

Which GPU is faster for gaming right now?

Quadro P5000 is the faster gaming card right now. In our data, it leads by 27.8% in average FPS across 50 tracked games in our benchmark data. PassMark G3D leans toward Radeon RX 6600S instead at 13,016 vs 12,728, so for this question the real-game FPS result matters more than the synthetic split.

Which GPU is the safer long-term pick for 2026 and beyond?

Radeon RX 6600S is the safer long-term pick for 2026 and beyond. The case is simple: the newer feature stack, with FSR 3 (2023) and FSR Frame Generation + AFMF (2023), while Quadro P5000 is limited to no meaningful modern upscaling stack and no comparable frame-generation support, a 7nm process instead of 16nm, 28 vs 0 ray-tracing units, and a newer 2022 generation instead of 2016. That gives it the more rounded hardware package for newer games.

Which GPU is the better buy today?

Radeon RX 6600S makes the most sense to buy today. It is $2,099 cheaper on MSRP at $400 vs $2,499, and it leads G3D-per-dollar by 538.9% (32.5 vs 5.1), which is enough to swing the recommendation its way. Quadro P5000 still makes more sense if max raw gaming performance matters more than value.

Quadro P5000 vs Radeon RX 6600S Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

Quadro P5000

The Quadro P5000 is manufactured by NVIDIA. It was released in October 1 2016. It features the Pascal architecture. The core clock ranges from 1607 MHz to 1733 MHz. It has 2048 shading units. The thermal design power (TDP) is 180W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 12,728 points. Launch price was $2,499.

Radeon RX 6600S

The Radeon RX 6600S is manufactured by AMD. It was released in January 4 2022. It features the RDNA 2.0 architecture. The core clock ranges from 1700 MHz to 2000 MHz. It has 1792 shading units. The thermal design power (TDP) is 80W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 13,016 points.

⚡

Graphics Performance

The Quadro P5000 scores 12,728 and the Radeon RX 6600S reaches 13,016 in the G3D Mark benchmark — just a 2.3% difference, making them near-identical in rasterization performance. The Quadro P5000 is built on Pascal while the Radeon RX 6600S uses RDNA 2.0, both on 16 nm vs 7 nm. Shader units: 2,048 (Quadro P5000) vs 1,792 (Radeon RX 6600S). Raw compute: 8.873 TFLOPS (Quadro P5000) vs 7.168 TFLOPS (Radeon RX 6600S). Boost clocks: 1733 MHz vs 2000 MHz.

Feature	Quadro P5000	Radeon RX 6600S
G3D Mark Score	12,728	13,016+2%
Architecture	Pascal	RDNA 2.0
Process Node	16 nm	7 nm
Shading Units	2048+14%	1792
Compute (TFLOPS)	8.873 TFLOPS+24%	7.168 TFLOPS
Boost Clock	1733 MHz	2000 MHz+15%
ROPs	64	64
TMUs	160+43%	112
L1 Cache	960 KB+88%	512 KB
L2 Cache	2 MB	2 MB

✨

Advanced Features (DLSS/FSR)

The clearest feature edge for the Radeon RX 6600S is support for FSR Frame Generation + AFMF. In games that support it, that can smooth out motion and lift perceived FPS. The Quadro P5000 does not have comparable native support in the same tier.

Feature	Quadro P5000	Radeon RX 6600S
Upscaling Tech	Upscaling support	FSR 3
Frame Generation	Not Supported	FSR Frame Generation + AFMF
Ray Reconstruction	No	No
Low Latency	Standard	AMD Anti-Lag

💾

Video Memory (VRAM)

The Quadro P5000 has 16 GB of VRAM, while the Radeon RX 6600S carries 4 GB. Quadro P5000 gives you 300% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bandwidth: 288 GB/s (Quadro P5000) vs 224 GB/s (Radeon RX 6600S) — a 28.6% advantage for the Quadro P5000. Memory bus width is 256-bit on the Quadro P5000 and 128-bit on the Radeon RX 6600S.

Feature	Quadro P5000	Radeon RX 6600S
VRAM Capacity	16 GB+300%	4 GB
Memory Type	GDDR5X	GDDR6
Memory Bandwidth	288 GB/s+29%	224 GB/s
Bus Width	256-bit+100%	128-bit
L2 Cache	2 MB	2 MB

🖥️

Display & API Support

DirectX support: 12.1 (Quadro P5000) vs 12_2 (Radeon RX 6600S). Vulkan: 1.0 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 0.

Feature	Quadro P5000	Radeon RX 6600S
DirectX	12.1	12_2
Vulkan	1.0	1.4+40%
OpenGL	4.6	4.6
Max Displays	4	0

🎬

Media & Encoding

Hardware encoder: 6th Gen NVENC (Quadro P5000) vs VCN 3.0 (Radeon RX 6600S). Decoder: 3rd Gen NVDEC vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro P5000) vs H.264,H.265/HEVC (Radeon RX 6600S).

Feature	Quadro P5000	Radeon RX 6600S
Encoder	6th Gen NVENC	VCN 3.0
Decoder	3rd Gen NVDEC	VCN 3.0
Codecs	MPEG-2,H.264,HEVC,VP9	H.264,H.265/HEVC

🔌

Power & Dimensions

The Quadro P5000 draws 180W versus the Radeon RX 6600S's 80W — a 76.9% difference. The Radeon RX 6600S is more power-efficient. Recommended PSU: 500W (Quadro P5000) vs 500W (Radeon RX 6600S). Power connectors: PCIe-powered vs Mobile. Card length: 267mm vs 1mm, occupying 2 vs 0 slots.

Feature	Quadro P5000	Radeon RX 6600S
TDP	180W	80W-56%
Recommended PSU	500W	500W
Power Connector	PCIe-powered	Mobile
Length	267mm	1mm
Height	111mm	—
Slots	2	0-100%
Temp (Load)	80°C	—
Perf/Watt	70.7	162.7+130%

💰

Value Analysis

At launch, the Quadro P5000 came in at $2499, while the Radeon RX 6600S launched at $400. On MSRP, Radeon RX 6600S was 84% cheaper ($2099 less). Performance per dollar on MSRP (G3D Mark / MSRP): 5.1 (Quadro P5000) vs 32.5 (Radeon RX 6600S) — the Radeon RX 6600S offers 537.3% better value. The newer card here is Radeon RX 6600S (2022 vs 2016).

Feature	Quadro P5000	Radeon RX 6600S
MSRP	$2499	$400-84%
Performance per Dollar	5.1	32.5+537%
Codename	GP104	Navi 23
Release	October 1 2016	January 4 2022
Ranking	#206	#200

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