Quadro RTX 4000 (Mobile) vs Radeon Instinct MI60

NVIDIA

Quadro RTX 4000 (Mobile)

2021Core: 780 MHzBoost: 1410 MHz
VS
AMD

Radeon Instinct MI60

2018Core: 1200 MHzBoost: 1800 MHz

Quadro RTX 4000 (Mobile) vs Radeon Instinct MI60 Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro RTX 4000 (Mobile) vs Radeon Instinct MI60 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro RTX 4000 (Mobile) vs Radeon Instinct MI60: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro RTX 4000 (Mobile)

2021

Why buy it

  • Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).
  • Better long-term bet: Turing (2018−2022) on 12nm gives it a newer hardware base for upcoming games.
  • Draws 40W instead of 300W, a 260W reduction.

Trade-offs

  • Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
  • Lower G3D Mark per dollar, at 0 vs 1.9 G3D/$ (Unknown MSRP vs $6,000 MSRP).

Radeon Instinct MI60

2018

Why buy it

  • 60.4% more average FPS across 50 tracked games in our benchmark data.
  • Delivers 100+% more G3D Mark for each dollar spent, at 1.9 vs 0 G3D/$ ($6,000 MSRP vs Unknown MSRP).

Trade-offs

  • No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).
  • Older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in newer AAA releases.
  • 650% higher power demand at 300W vs 40W.

Quick Answers

Which GPU is faster for gaming right now?
Radeon Instinct MI60 is the faster gaming card right now. In our data, it leads by 60.4% in average FPS across 50 tracked games in our benchmark data. PassMark G3D leans toward Quadro RTX 4000 (Mobile) instead at 11,715 vs 11,638, so for this question the real-game FPS result matters more than the synthetic split.
Which GPU is the safer long-term pick for 2026 and beyond?
Quadro RTX 4000 (Mobile) is the safer long-term pick for 2026 and beyond. The case is simple: native frame generation with DLSS 3.5 + Frame Generation (2023), while Radeon Instinct MI60 has no comparable frame-generation support and a newer 2021 generation instead of 2018. That makes it the less risky pick as game demands keep moving.
Which GPU is the better buy today?
Radeon Instinct MI60 makes the most sense today based on the pricing and value data we have for this matchup. If you are mainly targeting 1080p and some 1440p, Radeon Instinct MI60 is the easier value choice. If you care more about 1080p and some 1440p headroom, Quadro RTX 4000 (Mobile) has the stronger long-term case.

Quadro RTX 4000 (Mobile) vs Radeon Instinct MI60 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro RTX 4000 (Mobile)

The Quadro RTX 4000 (Mobile) is manufactured by NVIDIA. It was released in April 12 2021. It features the Turing architecture. The core clock ranges from 780 MHz to 1410 MHz. It has 896 shading units. The thermal design power (TDP) is 40W. Manufactured using 12 nm process technology. G3D Mark benchmark score: 11,715 points.

AMD

Radeon Instinct MI60

The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.

Graphics Performance

The Quadro RTX 4000 (Mobile) scores 11,715 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 0.7% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 (Mobile) is built on Turing while the Radeon Instinct MI60 uses GCN 5.1, both on 12 nm vs 7 nm. Shader units: 896 (Quadro RTX 4000 (Mobile)) vs 4,096 (Radeon Instinct MI60). Raw compute: 2.527 TFLOPS (Quadro RTX 4000 (Mobile)) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1410 MHz vs 1800 MHz.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
G3D Mark Score
11,715
11,638
Architecture
Turing
GCN 5.1
Process Node
12 nm
7 nm
Shading Units
896
4096+357%
Compute (TFLOPS)
2.527 TFLOPS
14.75 TFLOPS+484%
Boost Clock
1410 MHz
1800 MHz+28%
ROPs
32
64+100%
TMUs
56
256+357%
L1 Cache
0.88 MB
1 MB+14%
L2 Cache
1 MB
4 MB+300%

Advanced Features (DLSS/FSR)

The clearest feature edge for the Quadro RTX 4000 (Mobile) is support for DLSS 3.5 + Frame Generation. In games that support it, that can smooth out motion and lift perceived FPS. The Radeon Instinct MI60 does not have comparable native support in the same tier.The Quadro RTX 4000 (Mobile) gets NVIDIA DLSS, which still tends to look cleaner in motion. The Radeon Instinct MI60 leans on FSR, which is flexible and widely supported, but usually a bit rougher at the same settings.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
Upscaling Tech
DLSS 3.5 Super Resolution
FSR Upscaling / FSR 4
Frame Generation
DLSS 3.5 + Frame Generation
Not Supported
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards ship with 8 GB of GDDR6. Memory bus width is 256-bit on the Quadro RTX 4000 (Mobile) and 128-bit on the Radeon Instinct MI60. L2 Cache: 1 MB (Quadro RTX 4000 (Mobile)) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Bus Width
256-bit+100%
128-bit
L2 Cache
1 MB
4 MB+300%
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000 (Mobile)) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.1 vs 1.3. OpenGL: 4.6 vs 4.5. Maximum simultaneous displays: 4 vs 1.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
DirectX
12.2
12.1
Vulkan
1.1
1.3+18%
OpenGL
4.6+2%
4.5
Max Displays
4+300%
1
🎬

Media & Encoding

Hardware encoder: 7th Gen NVENC (Quadro RTX 4000 (Mobile)) vs VCE 4.1 (Radeon Instinct MI60). Decoder: 5th Gen NVDEC vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000 (Mobile)) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
Encoder
7th Gen NVENC
VCE 4.1
Decoder
5th Gen NVDEC
UVD 7.2
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro RTX 4000 (Mobile) draws 40W versus the Radeon Instinct MI60's 300W — a 152.9% difference. The Quadro RTX 4000 (Mobile) is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000 (Mobile)) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 0mm vs 267mm, occupying 0 vs 2 slots. Typical load temperature: 85°C vs 85°C.

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
TDP
40W-87%
300W
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
0mm
267mm
Height
0mm
111mm
Slots
0-100%
2
Temp (Load)
85°C
85°C
Perf/Watt
292.9+655%
38.8
💰

Value Analysis

The newer card here is Quadro RTX 4000 (Mobile) (2021 vs 2018).

FeatureQuadro RTX 4000 (Mobile)Radeon Instinct MI60
MSRP
$6000
Codename
TU117
Vega 20
Release
April 12 2021
November 18 2018
Ranking
#354
#232

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