Quadro RTX 4000 (Mobile) vs Radeon PRO W6600M

NVIDIA

Quadro RTX 4000 (Mobile)

2021Core: 780 MHzBoost: 1410 MHz

Popular choices:

VS
AMD

Radeon PRO W6600M

2021Core: 1224 MHzBoost: 2034 MHz

Popular choices:

Performance Spectrum - GPU

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, raw graphics performance, VRAM, feature set, power efficiency, pricing context, and long-term value so you can see which GPU actually makes more sense.

Quadro RTX 4000 (Mobile)

2021

Why buy it

  • Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).
  • Draws 40W instead of 90W, a 50W reduction.

Trade-offs

  • Fewer clear downsides in this head-to-head, aside from the usual pricing and availability swings.

Radeon PRO W6600M

2021

Why buy it

  • More future proof: RDNA 2.0 (2020−2025) on 7nm with a newer platform for upcoming games.

Trade-offs

  • No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).
  • 125% higher power demand at 90W vs 40W.

Quick Answers

So, is Quadro RTX 4000 (Mobile) better than Radeon PRO W6600M?
Yes, but this is not really about a huge raw performance gap. The broader synthetic picture is also very close at 11,715 vs 11,407 in G3D Mark. The bigger reason to prefer Quadro RTX 4000 (Mobile) is the overall package: you are getting DLSS 3.5 + Frame Generation, plus much lower power draw (40W vs 90W).
Which one is more future-proof for 2026 and beyond?
Quadro RTX 4000 (Mobile) is the more future-proof choice for 2026 and beyond. You are getting better frame-generation support with DLSS 3.5 + Frame Generation (2023) instead of FSR upscaling. That broader feature stack should age better as more games lean on modern upscaling and frame-generation support.
Which one is the smarter buy today, not just the cheaper card?
Quadro RTX 4000 (Mobile) can still make sense if you find it at the right price, especially around Unknown MSRP. Quadro RTX 4000 (Mobile) is still the smarter buy for most people, though, because the raw performance is close while the overall package is cleaner. Quadro RTX 4000 (Mobile) is priced in an unclear MSRP range at an unclear MSRP versus an unclear MSRP, and you are getting 2.7% higher G3D Mark. Moving to an unclear MSRP gets you lower power draw (40W vs 90W), and DLSS 3.5 + Frame Generation.
Is Radeon PRO W6600M still worth buying for gaming in 2026?
Yes. Radeon PRO W6600M is still a strong gaming card in 2026: it is still comfortable for 1080p and decent for 1440p, though 4K is more situational. Price is really the swing factor here. If you find it at or below an unclear MSRP, it remains a very sensible buy. Quadro RTX 4000 (Mobile) is still the safer recommendation for most fresh builds because it offers a cleaner overall package with DLSS 3.5 + Frame Generation.

Games Benchmarks

Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 9800X3D reference profile to minimize specific CPU bottlenecks.

Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.

Path of Exile 2

Path of Exile 2

PresetQuadro RTX 4000 (Mobile)Radeon PRO W6600M
1080p
low132 FPS140 FPS
medium111 FPS118 FPS
high93 FPS103 FPS
ultra56 FPS71 FPS
1440p
low113 FPS112 FPS
medium93 FPS92 FPS
high68 FPS75 FPS
ultra41 FPS52 FPS
4K
low40 FPS50 FPS
medium36 FPS43 FPS
high22 FPS32 FPS
ultra19 FPS28 FPS
Counter-Strike 2

Counter-Strike 2

PresetQuadro RTX 4000 (Mobile)Radeon PRO W6600M
1080p
low111 FPS243 FPS
medium87 FPS206 FPS
high68 FPS168 FPS
ultra52 FPS134 FPS
1440p
low81 FPS170 FPS
medium61 FPS142 FPS
high48 FPS112 FPS
ultra37 FPS88 FPS
4K
low50 FPS93 FPS
medium39 FPS78 FPS
high30 FPS65 FPS
ultra22 FPS49 FPS
League of Legends

League of Legends

PresetQuadro RTX 4000 (Mobile)Radeon PRO W6600M
1080p
low516 FPS513 FPS
medium422 FPS411 FPS
high351 FPS342 FPS
ultra264 FPS257 FPS
1440p
low377 FPS385 FPS
medium316 FPS308 FPS
high264 FPS257 FPS
ultra198 FPS192 FPS
4K
low227 FPS257 FPS
medium201 FPS205 FPS
high148 FPS171 FPS
ultra104 FPS128 FPS
Valorant

Valorant

PresetQuadro RTX 4000 (Mobile)Radeon PRO W6600M
1080p
low267 FPS262 FPS
medium227 FPS231 FPS
high184 FPS186 FPS
ultra146 FPS157 FPS
1440p
low197 FPS199 FPS
medium171 FPS176 FPS
high133 FPS138 FPS
ultra102 FPS113 FPS
4K
low108 FPS117 FPS
medium85 FPS99 FPS
high69 FPS79 FPS
ultra51 FPS60 FPS

Technical Specifications

Side-by-side comparison of Quadro RTX 4000 (Mobile) and Radeon PRO W6600M

NVIDIA

Quadro RTX 4000 (Mobile)

The Quadro RTX 4000 (Mobile) is manufactured by NVIDIA. It was released in April 12 2021. It features the Turing architecture. The core clock ranges from 780 MHz to 1410 MHz. It has 896 shading units. The thermal design power (TDP) is 40W. Manufactured using 12 nm process technology. G3D Mark benchmark score: 11,715 points.

AMD

Radeon PRO W6600M

The Radeon PRO W6600M is manufactured by AMD. It was released in June 8 2021. It features the RDNA 2.0 architecture. The core clock ranges from 1224 MHz to 2034 MHz. It has 1792 shading units. The thermal design power (TDP) is 90W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 11,407 points.

Graphics Performance

The Quadro RTX 4000 (Mobile) scores 11,715 and the Radeon PRO W6600M reaches 11,407 in the G3D Mark benchmark — just a 2.7% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 (Mobile) is built on Turing while the Radeon PRO W6600M uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 896 (Quadro RTX 4000 (Mobile)) vs 1,792 (Radeon PRO W6600M). Raw compute: 2.527 TFLOPS (Quadro RTX 4000 (Mobile)) vs 7.29 TFLOPS (Radeon PRO W6600M). Boost clocks: 1410 MHz vs 2034 MHz.

FeatureQuadro RTX 4000 (Mobile)Radeon PRO W6600M
G3D Mark Score
11,715+3%
11,407
Architecture
Turing
RDNA 2.0
Process Node
12 nm
7 nm
Shading Units
896
1792+100%
Compute (TFLOPS)
2.527 TFLOPS
7.29 TFLOPS+188%
Boost Clock
1410 MHz
2034 MHz+44%
ROPs
32
64+100%
TMUs
56
112+100%
L1 Cache
896 KB+75%
512 KB
L2 Cache
1 MB
2 MB+100%

Advanced Features (DLSS/FSR)

A critical advantage for the Quadro RTX 4000 (Mobile) is support for DLSS 3.5 + Frame Generation. This allows it to generate entire frames using AI/Algorithms, essentially doubling the frame rate in CPU-bound scenarios or heavy ray-tracing titles. The Radeon PRO W6600M lacks specific hardware/driver support for this native frame generation tier.The Quadro RTX 4000 (Mobile) gives access to NVIDIA DLSS (Deep Learning Super Sampling), widely regarding as the superior upscaling method for image quality. The Radeon PRO W6600M relies on FSR (FidelityFX Super Resolution), which is capable but generally slightly noisier than DLSS in motion.

FeatureQuadro RTX 4000 (Mobile)Radeon PRO W6600M
Upscaling Tech
DLSS 3.5 Super Resolution
FSR Upscaling / FSR 4
Frame Generation
DLSS 3.5 + Frame Generation
Not Supported
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards feature 8 GB of GDDR6. Bus width: 256-bit vs 256-bit. L2 Cache: 1 MB (Quadro RTX 4000 (Mobile)) vs 2 MB (Radeon PRO W6600M) — the Radeon PRO W6600M has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000 (Mobile)Radeon PRO W6600M
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Bus Width
256-bit
256-bit
L2 Cache
1 MB
2 MB+100%
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000 (Mobile)) vs 12.2 (Radeon PRO W6600M). Vulkan: 1.1 vs 1.2. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 5.

FeatureQuadro RTX 4000 (Mobile)Radeon PRO W6600M
DirectX
12.2
12.2
Vulkan
1.1
1.2+9%
OpenGL
4.6
4.6
Max Displays
4
5+25%
🎬

Media & Encoding

Hardware encoder: 7th Gen NVENC (Quadro RTX 4000 (Mobile)) vs VCN 3.0 (Radeon PRO W6600M). Decoder: 5th Gen NVDEC vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000 (Mobile)) vs MPEG-2,H.264,HEVC,VP9,AV1 (Decode) (Radeon PRO W6600M).

FeatureQuadro RTX 4000 (Mobile)Radeon PRO W6600M
Encoder
7th Gen NVENC
VCN 3.0
Decoder
5th Gen NVDEC
VCN 3.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9,AV1 (Decode)
🔌

Power & Dimensions

The Quadro RTX 4000 (Mobile) draws 40W versus the Radeon PRO W6600M's 90W — a 76.9% difference. The Quadro RTX 4000 (Mobile) is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000 (Mobile)) vs 500W (Radeon PRO W6600M). Power connectors: PCIe-powered vs PCIe-powered. Card length: 0mm vs 0mm, occupying 0 vs 0 slots. Typical load temperature: 85°C vs 80°C.

FeatureQuadro RTX 4000 (Mobile)Radeon PRO W6600M
TDP
40W-56%
90W
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
0mm
0mm
Height
0mm
0mm
Slots
0
0
Temp (Load)
85°C
80°C-6%
Perf/Watt
292.9+131%
126.7