
Ryzen Threadripper PRO 3975WX vs EPYC 7543

Ryzen Threadripper PRO 3975WX

EPYC 7543
Performance Spectrum - CPU
About PassMark
PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.
Value Upgrade Path
This is the official ChipVERSUS Value Rating, comparing raw performance (PassMark) per dollar. Components placed above yours deliver better value for money.
Avg price is the current average price collected from markets across the web.
Performance Per Dollar Ryzen Threadripper PRO 3975WX
Performance Per Dollar EPYC 7543
Performance Comparison
About PassMark🏆 Chipversus Verdict
🚀 Performance Leadership
| Insight | Ryzen Threadripper PRO 3975WX | EPYC 7543 |
|---|---|---|
| Gaming | ✅ Superior gaming performance | ❌ Lower gaming performance |
| Workstation | ❌ Weaker in multi-core tasks | ✅ Better multi-core power |
| Price | ✅ More affordable ($368) | ⚠️ Higher cost ($468) |
| Longevity | ✨ Modern (Matisse (2019−2020) / 7 nm, 12 nm) | ✨ Modern (Milan (2021−2023) / 7 nm+) |
💎 Value Proposition
| Insight | Ryzen Threadripper PRO 3975WX | EPYC 7543 |
|---|---|---|
| Cost Efficiency | ✅ Better overall value (+26%) | ❌ Lower cost efficiency |
| Upfront Cost | ✅ More affordable ($368) | ⚠️ Higher cost ($468) |
Performance Check
To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.
Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.
Technical Specifications
Side-by-side comparison of Ryzen Threadripper PRO 3975WX and EPYC 7543

Ryzen Threadripper PRO 3975WX
The Ryzen Threadripper PRO 3975WX is manufactured by AMD. It was released in 2020-07-14. It is based on the Matisse (2019−2020) architecture. It features 32 cores and 64 threads. Base frequency is 3.5 GHz, with boost up to 4.2 GHz. L3 cache: 128 MB. L2 cache: 512K (per core). Built on 7 nm, 12 nm process technology. Socket: sWRX8. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,261 points. Launch price was $4,499.

EPYC 7543
The EPYC 7543 is manufactured by AMD. It was released in 15 March 2021 (4 years ago). It is based on the Milan (2021−2023) architecture. It features 32 cores and 64 threads. Base frequency is 2.8 GHz, with boost up to 3.7 GHz. L3 cache: 256 MB (total). L2 cache: 512 kB (per core). Built on 7 nm+ process technology. Socket: SP3. Thermal design power (TDP): 225 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,952 points. Launch price was $3,761.
Processing Power
Both the Ryzen Threadripper PRO 3975WX and EPYC 7543 share an identical 32-core/64-thread configuration. Boost clocks reach 4.2 GHz on the Ryzen Threadripper PRO 3975WX versus 3.7 GHz on the EPYC 7543 — a 12.7% clock advantage for the Ryzen Threadripper PRO 3975WX (base: 3.5 GHz vs 2.8 GHz). The Ryzen Threadripper PRO 3975WX uses the Matisse (2019−2020) architecture (7 nm, 12 nm), while the EPYC 7543 uses Milan (2021−2023) (7 nm+). In PassMark, the Ryzen Threadripper PRO 3975WX scores 62,261 against the EPYC 7543's 62,952 — a 1.1% lead for the EPYC 7543. L3 cache: 128 MB on the Ryzen Threadripper PRO 3975WX vs 256 MB (total) on the EPYC 7543.
| Feature | Ryzen Threadripper PRO 3975WX | EPYC 7543 |
|---|---|---|
| Cores / Threads | 32 / 64 | 32 / 64 |
| Boost Clock | 4.2 GHz+14% | 3.7 GHz |
| Base Clock | 3.5 GHz+25% | 2.8 GHz |
| L3 Cache | 128 MB | 256 MB (total)+100% |
| L2 Cache | 512K (per core) | 512 kB (per core) |
| Process | 7 nm, 12 nm | 7 nm+ |
| Architecture | Matisse (2019−2020) | Milan (2021−2023) |
| PassMark | 62,261 | 62,952+1% |
| Cinebench R23 Multi | 42,986 | — |
| Geekbench 6 Single | 1,260 | — |
| Geekbench 6 Multi | 25,211 | — |
Memory & Platform
The Ryzen Threadripper PRO 3975WX uses the sWRX8 socket (PCIe 4.0), while the EPYC 7543 uses SP3 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches DDR4-3200 on the Ryzen Threadripper PRO 3975WX versus 3200 on the EPYC 7543 — the EPYC 7543 supports 199.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7543 supports up to 4096 of RAM compared to 2048 GB — 66.7% more capacity for professional workloads. Both feature 8-channel memory with ECC support. Both provide 128 PCIe lanes. Chipset compatibility: AMD WRX80 (Ryzen Threadripper PRO 3975WX) and SP3 (EPYC 7543).
| Feature | Ryzen Threadripper PRO 3975WX | EPYC 7543 |
|---|---|---|
| Socket | sWRX8 | SP3 |
| PCIe Generation | PCIe 4.0 | PCIe 4.0 |
| Max RAM Speed | DDR4-3200 | 3200+79900% |
| Max RAM Capacity | 2048 GB+52428700% | 4096 |
| RAM Channels | 8 | 8 |
| ECC Support | ✅ | ✅ |
| PCIe Lanes | 128 | 128 |
Advanced Features
Only the Ryzen Threadripper PRO 3975WX has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Virtualization support: true (Ryzen Threadripper PRO 3975WX) vs VT-x, VT-d (EPYC 7543). Direct competitor: Ryzen Threadripper PRO 3975WX rivals Xeon W-3375; EPYC 7543 rivals Xeon Platinum 8380.
| Feature | Ryzen Threadripper PRO 3975WX | EPYC 7543 |
|---|---|---|
| Integrated GPU | No | No |
| IGPU Model | None | None |
| Unlocked | Yes | No |
| AVX-512 | No | No |
| Virtualization | true | VT-x, VT-d |
Value Analysis
The Ryzen Threadripper PRO 3975WX launched at $1337 MSRP, while the EPYC 7543 debuted at $10257. At current prices ($368 vs $468), the Ryzen Threadripper PRO 3975WX is $100 cheaper. In terms of value (PassMark points per dollar), the Ryzen Threadripper PRO 3975WX delivers 169.2 pts/$ vs 134.5 pts/$ for the EPYC 7543 — making the Ryzen Threadripper PRO 3975WX the 22.8% better value option.
| Feature | Ryzen Threadripper PRO 3975WX | EPYC 7543 |
|---|---|---|
| MSRP | $1337-87% | $10257 |
| Avg Price (30d) | $368-21% | $468 |
| Performance per Dollar | 169.2+26% | 134.5 |
| Release Date | 2020 | 2021 |
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