EPYC 4565P vs Xeon Platinum 8380

CPU

GPU

EPYC 4565P

16 Cores32 Thrd170 WWMax: 5.7 GHz2025

EPYC family

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Xeon Platinum 8380

40 Cores80 Thrd270 WWMax: 3.4 GHz2021

Similar parts

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EPYC 4565P vs Xeon Platinum 8380 Performance Spectrum

EPYC 4565P

16 / 32

64,068

+2.8%

Ryzen 7 7700X

Ryzen 7 8840HX

Ryzen Threadripper PRO 7945WX

Ryzen Threadripper PRO 9945WX

Ryzen Threadripper 3990X

Ryzen Threadripper 9960X

Ryzen Threadripper PRO 9975WX

Ryzen Threadripper PRO 7985WX

Xeon Platinum 8380

40 / 80

62,318

0.0%

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

EPYC 4565P vs Xeon Platinum 8380 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

EPYC 4565P vs Xeon Platinum 8380: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

EPYC 4565P

2025

Why buy it

✅Better for gaming: +26.6% higher average FPS across 50 shared CPU benchmark tests.
✅Draws 170W instead of 270W, a 100W reduction.
✅Newer platform on AM5 with DDR5 support instead of LGA4189 and DDR4.
✅Integrated graphics onboard with AMD Radeon Graphics, while Xeon Platinum 8380 needs a discrete GPU.

Trade-offs

❌Lower PassMark per dollar, at 23.5 vs 31.0 PassMark/$ ($2,730 MSRP vs $2,010 MSRP).

Xeon Platinum 8380

2021

Why buy it

✅Costs $720 less on MSRP ($2,010 MSRP vs $2,730 MSRP).
✅Delivers 32.1% more PassMark for each dollar spent, at 31.0 vs 23.5 PassMark/$ ($2,010 MSRP vs $2,730 MSRP).
✅128.6% more PCIe lanes (64 vs 28) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 4565P across 50 shared CPU benchmark tests.
❌Lower PassMark (62,318 vs 64,068).
❌58.8% higher power demand at 270W vs 170W.
❌Older platform position on LGA4189 with DDR4, while EPYC 4565P moves to AM5 and DDR5.
❌No integrated graphics, while EPYC 4565P can still boot and troubleshoot without a discrete GPU.

Quick Answers

So, is EPYC 4565P better than Xeon Platinum 8380?

Yes. EPYC 4565P is the better all-around CPU here. It gives you a 26.6% average FPS lead across 50 shared CPU game tests in our data, 2.8% better PassMark, and the stronger long-term platform, which is enough to make it the stronger overall pick.

Which one is better for gaming?

If gaming is the priority, EPYC 4565P is the better pick. According to our tests, it delivers 26.6% more average FPS across 50 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, EPYC 4565P is the stronger fit. You are getting 2.8% better PassMark, backed by 16 cores and 32 threads.

Which one is the smarter buy today, not just the cheaper CPU?

EPYC 4565P is still the faster CPU overall, but Xeon Platinum 8380 is easier to justify if budget matters more than peak performance. EPYC 4565P comes in 35.8% more expensive on MSRP at $2,730 MSRP versus $2,010 MSRP, and it still gives you a 26.6% average FPS lead across 50 shared CPU game tests in our data. Xeon Platinum 8380 is also 32.1% better value on MSRP (31.0 vs 23.5 PassMark/$), which is why it can still make sense for tighter-budget builds on paper.

Which one is more future-proof for 2026 and beyond?

EPYC 4565P makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2021), a healthier platform with AM5 and DDR5 instead of LGA4189, and more multi-core headroom with 16 cores / 32 threads instead of 40/80. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

EPYC 4565P vs Xeon Platinum 8380 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

EPYC 4565P

The EPYC 4565P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 16 cores and 32 threads. Base frequency is 4.3 GHz, with boost up to 5.7 GHz. L3 cache: 64 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 170 Watt. Memory support: DDR5. Passmark benchmark score: 64,068 points. Launch price was $589.

Xeon Platinum 8380

The Xeon Platinum 8380 is manufactured by Intel. It was released in 2021-04-06. It is based on the Ice Lake-SP (2021) architecture. It features 40 cores and 80 threads. Base frequency is 2.3 GHz, with boost up to 3.4 GHz. L3 cache: 60 MB (total). L2 cache: 1 MB (per core). Built on 10 nm process technology. Socket: LGA4189. Thermal design power (TDP): 270 Watt. Memory support: DDR4-3200. Passmark benchmark score: 62,318 points. Launch price was $5,846.

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Processing Power

The EPYC 4565P packs 16 cores / 32 threads, while the Xeon Platinum 8380 offers 40 cores / 80 threads — the Xeon Platinum 8380 has 24 more cores. Boost clocks reach 5.7 GHz on the EPYC 4565P versus 3.4 GHz on the Xeon Platinum 8380 — a 50.5% clock advantage for the EPYC 4565P (base: 4.3 GHz vs 2.3 GHz). The EPYC 4565P uses the Grado (2025) architecture (4 nm), while the Xeon Platinum 8380 uses Ice Lake-SP (2021) (10 nm). In PassMark, the EPYC 4565P scores 64,068 against the Xeon Platinum 8380's 62,318 — a 2.8% lead for the EPYC 4565P. L3 cache: 64 MB (total) on the EPYC 4565P vs 60 MB (total) on the Xeon Platinum 8380.

Feature	EPYC 4565P	Xeon Platinum 8380
Cores / Threads	16 / 32	40 / 80+150%
Boost Clock	5.7 GHz+68%	3.4 GHz
Base Clock	4.3 GHz+87%	2.3 GHz
L3 Cache	64 MB (total)+7%	60 MB (total)
L2 Cache	1 MB (per core)	1 MB (per core)
Process	4 nm-60%	10 nm
Architecture	Grado (2025)	Ice Lake-SP (2021)
PassMark	64,068+3%	62,318
Geekbench 6 Single	—	1,300
Geekbench 6 Multi	—	40,000

🧠

Memory & Platform

The EPYC 4565P uses the AM5 socket (PCIe 4.0), while the Xeon Platinum 8380 uses LGA4189 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4565P versus DDR4-3200 on the Xeon Platinum 8380 — the EPYC 4565P supports 75% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon Platinum 8380 supports up to 6144 GB of RAM compared to 192 GB — 3100% more capacity for professional workloads. Memory channels: 2 (EPYC 4565P) vs 8 (Xeon Platinum 8380). PCIe lanes: 28 (EPYC 4565P) vs 64 (Xeon Platinum 8380) — the Xeon Platinum 8380 offers 36 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4565P) and C621A (Xeon Platinum 8380).

Feature	EPYC 4565P	Xeon Platinum 8380
Socket	AM5	LGA4189
PCIe Generation	PCIe 4.0	PCIe 4.0
Max RAM Speed	5600+75%	DDR4-3200
Max RAM Capacity	192 GB	6144 GB+3100%
RAM Channels	2	8+300%
ECC Support	Yes	Yes
PCIe Lanes	28	64+129%

🔧

Advanced Features

Only the EPYC 4565P has an unlocked multiplier for overclocking — a significant advantage for enthusiasts seeking extra performance. Both support AVX-512 instructions, benefiting scientific computing, AI inference, and encryption workloads. Virtualization support: VT-x, VT-d, AMD-V (EPYC 4565P) vs VT-x, VT-d (Xeon Platinum 8380). The EPYC 4565P includes integrated graphics (AMD Radeon Graphics), while the Xeon Platinum 8380 requires a dedicated GPU. Primary use case: Xeon Platinum 8380 targets Datacenter. Direct competitor: EPYC 4565P rivals Core Ultra 9 285K; Xeon Platinum 8380 rivals EPYC 7543.

Feature	EPYC 4565P	Xeon Platinum 8380
Integrated GPU	Yes	No
IGPU Model	AMD Radeon Graphics	None
Unlocked	Yes	No
AVX-512	Yes	Yes
Virtualization	VT-x, VT-d, AMD-V	VT-x, VT-d
Target Use	—	Datacenter

💰

Value Analysis

At launch, the EPYC 4565P was priced at $2730, while the Xeon Platinum 8380 came in at $2010. On launch pricing ($2730 vs $2010), Xeon Platinum 8380 was $720 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4565P delivers 23.5 pts/$ vs 31.0 pts/$ for the Xeon Platinum 8380 — making the Xeon Platinum 8380 the 27.7% better value option.

Feature	EPYC 4565P	Xeon Platinum 8380
MSRP	$2730	$2010-26%
Performance per Dollar	23.5	31.0+32%
Release Date	2025	2021

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