EPYC 7501 vs Xeon Gold 6143

AMD

EPYC 7501

32 Cores64 Thrd155 WWMax: 3 GHz2017

Popular choices:

VS
Intel

Xeon Gold 6143

16 Cores32 Thrd205 WWMax: 4 GHz2017

Popular choices:

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 7501

2017

Why buy it

  • +0.6% higher PassMark.
  • +190.9% larger total L3 cache (64 MB vs 22 MB).
  • Draws 155W instead of 205W, a 50W reduction.

Trade-offs

  • Worse for gaming: lower average FPS than Xeon Gold 6143 across 4 shared CPU benchmark tests.

Xeon Gold 6143

2017

Why buy it

  • Better for gaming: +31.5% higher average FPS across 4 shared CPU benchmark tests.

Trade-offs

  • Lower PassMark (24,786 vs 24,925).
  • Smaller total L3 cache (22 MB vs 64 MB).
  • Launch MSRP is still $342 MSRP, while EPYC 7501 mostly shows up through inconsistent older-market listings.
  • 32.3% higher power demand at 205W vs 155W.

Quick Answers

So, is EPYC 7501 better than Xeon Gold 6143?
It depends on what matters more to you. For gaming, Xeon Gold 6143 is ahead with a 31.5% average FPS lead across 4 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, EPYC 7501 pulls ahead with 0.6% better PassMark. EPYC 7501 also has the bigger cache pool with 190.9% larger total L3 cache (64 MB vs 22 MB).
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 7501 is the better fit. You are getting 0.6% better PassMark, backed by 32 cores and 64 threads. It also carries the larger cache pool with 190.9% larger total L3 cache (64 MB vs 22 MB).
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 7501 is still the faster CPU overall, but Xeon Gold 6143 makes more sense if price matters more than absolute performance. EPYC 7501 is at an unclear MSRP at unclear MSRP versus $342 MSRP, and it gives you 0.6% better PassMark. The trade-off is that Xeon Gold 6143 is still the better pure gaming CPU with a 31.5% average FPS lead across 4 shared CPU game tests in our data. Xeon Gold 6143 is also 100.0% better value on MSRP (72.5 vs 0.0 PassMark/$), which is why it is easier to justify for price-conscious builds on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 7501 is the more future-proof choice for 2026 and beyond. You are getting 190.9% larger total L3 cache (64 MB vs 22 MB) and more multi-core headroom with 32 cores / 64 threads instead of 16/32. That extra compute headroom should age better as games, background tasks, and creator workloads get heavier.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Path of Exile 2

Path of Exile 2

PresetEPYC 7501Xeon Gold 6143
1080p
low187 FPS183 FPS
medium165 FPS147 FPS
high132 FPS119 FPS
ultra105 FPS93 FPS
1440p
low153 FPS146 FPS
medium127 FPS114 FPS
high97 FPS92 FPS
ultra78 FPS72 FPS
4K
low71 FPS68 FPS
medium63 FPS57 FPS
high48 FPS45 FPS
ultra39 FPS36 FPS
Counter-Strike 2

Counter-Strike 2

PresetEPYC 7501Xeon Gold 6143
1080p
low207 FPS397 FPS
medium188 FPS343 FPS
high160 FPS286 FPS
ultra131 FPS240 FPS
1440p
low178 FPS344 FPS
medium163 FPS305 FPS
high141 FPS254 FPS
ultra111 FPS212 FPS
4K
low112 FPS222 FPS
medium103 FPS198 FPS
high92 FPS176 FPS
ultra75 FPS144 FPS
League of Legends

League of Legends

PresetEPYC 7501Xeon Gold 6143
1080p
low620 FPS620 FPS
medium518 FPS620 FPS
high466 FPS620 FPS
ultra399 FPS620 FPS
1440p
low517 FPS620 FPS
medium432 FPS620 FPS
high378 FPS620 FPS
ultra325 FPS589 FPS
4K
low383 FPS514 FPS
medium308 FPS420 FPS
high270 FPS370 FPS
ultra220 FPS302 FPS
Valorant

Valorant

PresetEPYC 7501Xeon Gold 6143
1080p
low623 FPS620 FPS
medium623 FPS620 FPS
high623 FPS620 FPS
ultra561 FPS620 FPS
1440p
low623 FPS620 FPS
medium584 FPS620 FPS
high500 FPS614 FPS
ultra420 FPS519 FPS
4K
low475 FPS587 FPS
medium427 FPS516 FPS
high375 FPS453 FPS
ultra320 FPS380 FPS

Technical Specifications

Side-by-side comparison of EPYC 7501 and Xeon Gold 6143

AMD

EPYC 7501

The EPYC 7501 is manufactured by AMD. It was released in 29 June 2017 (8 years ago). It is based on the Naples (2017−2018) architecture. It features 32 cores and 64 threads. Base frequency is 2 GHz, with boost up to 3 GHz. L3 cache: 64 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: TR4. Thermal design power (TDP): 170 Watt. Memory support: DDR4 Eight-channel. Passmark benchmark score: 24,925 points. Launch price was $3,400.

Intel

Xeon Gold 6143

The Xeon Gold 6143 is manufactured by Intel. It was released in 2015-01-01. It features 16 cores and 32 threads. Base frequency is 2.8 GHz, with boost up to 4 GHz. L3 cache: 22 MB. Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 205 Watt. Memory support: DDR4-2666. Passmark benchmark score: 24,786 points. Launch price was $800.

Processing Power

The EPYC 7501 packs 32 cores / 64 threads, while the Xeon Gold 6143 offers 16 cores / 32 threads — the EPYC 7501 has 16 more cores. Boost clocks reach 3 GHz on the EPYC 7501 versus 4 GHz on the Xeon Gold 6143 — a 28.6% clock advantage for the Xeon Gold 6143 (base: 2 GHz vs 2.8 GHz). The EPYC 7501 is built on the Naples (2017−2018) architecture. In PassMark, the EPYC 7501 scores 24,925 against the Xeon Gold 6143's 24,786 — a 0.6% lead for the EPYC 7501. L3 cache: 64 MB (total) on the EPYC 7501 vs 22 MB on the Xeon Gold 6143.

FeatureEPYC 7501Xeon Gold 6143
Cores / Threads
32 / 64+100%
16 / 32
Boost Clock
3 GHz
4 GHz+33%
Base Clock
2 GHz
2.8 GHz+40%
L3 Cache
64 MB (total)+191%
22 MB
L2 Cache
512K (per core)
Process
14 nm
14 nm
Architecture
Naples (2017−2018)
PassMark
24,925
24,786
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Memory & Platform

The EPYC 7501 uses the TR4 socket (PCIe 4.0), while the Xeon Gold 6143 uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard.

FeatureEPYC 7501Xeon Gold 6143
Socket
TR4
LGA3647
PCIe Generation
PCIe 4.0+33%
PCIe 3.0