Quadro RTX 5000 vs Radeon RX 6600

NVIDIA

Quadro RTX 5000

2018Core: 1620 MHzBoost: 1815 MHz
Similar parts
·······
VS
AMD

Radeon RX 6600

2021Core: 1626 MHzBoost: 2491 MHz
RX family
·······

Quadro RTX 5000 vs Radeon RX 6600 Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro RTX 5000 vs Radeon RX 6600 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro RTX 5000 vs Radeon RX 6600: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro RTX 5000

2018

Why buy it

  • 27.5% more average FPS across 50 tracked games in our benchmark data.
  • 100% more VRAM for high-resolution textures and newer games (16 GB vs 8 GB).

Trade-offs

  • Radeon RX 6600 is the safer long-term pick here because the hardware is newer and the feature stack is stronger.
  • 598.8% HIGHER MSRP
    $2,299 MSRPvs$329 MSRP
  • Lower G3D Mark per dollar, at 6.7 vs 45.9 G3D/$ ($2,299 MSRP vs $329 MSRP).
  • 74.2% higher power demand at 230W vs 132W.

Radeon RX 6600

2021

Why buy it

  • Costs $1,970 less on MSRP ($329 MSRP vs $2,299 MSRP).
  • Delivers 582.8% more G3D Mark for each dollar spent, at 45.9 vs 6.7 G3D/$ ($329 MSRP vs $2,299 MSRP).
  • Better long-term bet: RDNA 2.0 (2020−2025) on 7nm gives it a newer hardware base for upcoming games.
  • Draws 132W instead of 230W, a 98W reduction.

Trade-offs

  • Lower average FPS than Quadro RTX 5000 across 50 tracked games in our benchmark data.
  • Less VRAM, with 8 GB vs 16 GB for high-resolution textures and newer games.

Quick Answers

Which GPU is faster for gaming right now?
Quadro RTX 5000 is the faster gaming card right now. In our data, it leads by 27.5% in average FPS across 50 tracked games in our benchmark data and by 2.3% in PassMark G3D (15,443 vs 15,089), so the answer here is pretty clean.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon RX 6600 is the safer long-term pick for 2026 and beyond. The case is simple: a 7nm process instead of 12nm and a newer 2021 generation instead of 2018. That makes it the less risky pick as game demands keep moving.
Which GPU is the better buy today?
Radeon RX 6600 makes the most sense to buy today. It is $1,970 cheaper on MSRP at $329 vs $2,299, and it leads G3D-per-dollar by 582.8% (45.9 vs 6.7), which is enough to swing the recommendation its way. Quadro RTX 5000 still makes more sense if max raw gaming performance matters more than value.

Quadro RTX 5000 vs Radeon RX 6600 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro RTX 5000

The Quadro RTX 5000 is manufactured by NVIDIA. It was released in August 13 2018. It features the Turing architecture. The core clock ranges from 1620 MHz to 1815 MHz. It has 3072 shading units. The thermal design power (TDP) is 230W. Manufactured using 12 nm process technology. It features 48 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 15,443 points. Launch price was $2,299.

AMD

Radeon RX 6600

The Radeon RX 6600 is manufactured by AMD. It was released in October 13 2021. It features the RDNA 2.0 architecture. The core clock ranges from 1626 MHz to 2491 MHz. It has 1792 shading units. The thermal design power (TDP) is 132W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 15,089 points. Launch price was $329.

Graphics Performance

The Quadro RTX 5000 scores 15,443 and the Radeon RX 6600 reaches 15,089 in the G3D Mark benchmark — just a 2.3% difference, making them near-identical in rasterization performance. The Quadro RTX 5000 is built on Turing while the Radeon RX 6600 uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 3,072 (Quadro RTX 5000) vs 1,792 (Radeon RX 6600). Raw compute: 11.15 TFLOPS (Quadro RTX 5000) vs 8.928 TFLOPS (Radeon RX 6600). Boost clocks: 1815 MHz vs 2491 MHz. Ray tracing: 48 RT cores (Quadro RTX 5000) vs 28 (Radeon RX 6600) with 384 Tensor cores.

FeatureQuadro RTX 5000Radeon RX 6600
G3D Mark Score
15,443+2%
15,089
Architecture
Turing
RDNA 2.0
Process Node
12 nm
7 nm
Shading Units
3072+71%
1792
Compute (TFLOPS)
11.15 TFLOPS+25%
8.928 TFLOPS
Boost Clock
1815 MHz
2491 MHz+37%
ROPs
64
64
TMUs
192+71%
112
L1 Cache
3 MB+500%
0.5 MB
L2 Cache
4 MB+100%
2 MB
Ray Tracing Cores
48+71%
28

Advanced Features (DLSS/FSR)

Both GPUs support Frame Generation, but they get there through different ecosystems. The Quadro RTX 5000 uses DLSS 4 Multi Frame Generation, while the Radeon RX 6600 relies on FSR Frame Generation + AFMF. Both can help smooth out supported games, but they are not on the same feature stack.The Quadro RTX 5000 gets NVIDIA DLSS, which still tends to look cleaner in motion. The Radeon RX 6600 leans on FSR, which is flexible and widely supported, but usually a bit rougher at the same settings.

FeatureQuadro RTX 5000Radeon RX 6600
Upscaling Tech
DLSS 4 Super Resolution
FSR 3
Frame Generation
DLSS 4 Multi Frame Generation
FSR Frame Generation + AFMF
Ray Reconstruction
Yes (DLSS 4)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro RTX 5000 has 16 GB of VRAM, while the Radeon RX 6600 carries 8 GB. Quadro RTX 5000 gives you 100% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bandwidth: 448 GB/s (Quadro RTX 5000) vs 224 GB/s (Radeon RX 6600) — a 100% advantage for the Quadro RTX 5000. Memory bus width is 256-bit on the Quadro RTX 5000 and 128-bit on the Radeon RX 6600. L2 Cache: 4 MB (Quadro RTX 5000) vs 2 MB (Radeon RX 6600) — the Quadro RTX 5000 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 5000Radeon RX 6600
VRAM Capacity
16 GB+100%
8 GB
Memory Type
GDDR6
GDDR6
Memory Bandwidth
448 GB/s+100%
224 GB/s
Bus Width
256-bit+100%
128-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12 Ultimate (Quadro RTX 5000) vs 12 Ultimate (Radeon RX 6600). Vulkan: 1.4 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 4.

FeatureQuadro RTX 5000Radeon RX 6600
DirectX
12 Ultimate
12 Ultimate
Vulkan
1.4
1.4
OpenGL
4.6
4.6
Max Displays
4
4
🎬

Media & Encoding

Hardware encoder: NVENC (7th Gen) (Quadro RTX 5000) vs VCE (Radeon RX 6600). Decoder: NVDEC (4th Gen) vs UVD. Supported codecs: H.264,HEVC,AV1 (Decode),VP9 (Quadro RTX 5000) vs H.264,H.265/HEVC,AV1 (Radeon RX 6600).

FeatureQuadro RTX 5000Radeon RX 6600
Encoder
NVENC (7th Gen)
VCE
Decoder
NVDEC (4th Gen)
UVD
Codecs
H.264,HEVC,AV1 (Decode),VP9
H.264,H.265/HEVC,AV1
🔌

Power & Dimensions

The Quadro RTX 5000 draws 230W versus the Radeon RX 6600's 132W — a 54.1% difference. The Radeon RX 6600 is more power-efficient. Recommended PSU: 650W (Quadro RTX 5000) vs 450W (Radeon RX 6600). Power connectors: PCIe-powered vs 1x 8-pin. Typical load temperature: 75°C vs 70°C.

FeatureQuadro RTX 5000Radeon RX 6600
TDP
230W
132W-43%
Recommended PSU
650W
450W-31%
Power Connector
PCIe-powered
1x 8-pin
Length
190mm
Height
110mm
Slots
2
2
Temp (Load)
75°C
70°C-7%
Perf/Watt
67.1
114.3+70%
💰

Value Analysis

At launch, the Quadro RTX 5000 came in at $2299, while the Radeon RX 6600 launched at $329. On MSRP, Radeon RX 6600 was 85.7% cheaper ($1970 less). Performance per dollar on MSRP (G3D Mark / MSRP): 6.7 (Quadro RTX 5000) vs 45.9 (Radeon RX 6600) — the Radeon RX 6600 offers 585.1% better value. The newer card here is Radeon RX 6600 (2021 vs 2018).

FeatureQuadro RTX 5000Radeon RX 6600
MSRP
$2299
$329-86%
Performance per Dollar
6.7
45.9+585%
Codename
TU104
Navi 23
Release
August 13 2018
October 13 2021
Ranking
#143
#150

Affiliate Disclosure

ChipVERSUS is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. We may earn a commission on qualifying purchases made through our links. This comes at no additional cost to you and helps support our work in providing comprehensive PC building guides and tools.

Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.