Quadro M6000 vs Radeon Instinct MI60

NVIDIA

Quadro M6000

2015Core: 988 MHzBoost: 1114 MHz
Similar parts
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VS
AMD

Radeon Instinct MI60

2018Core: 1200 MHzBoost: 1800 MHz
Similar parts
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Quadro M6000 vs Radeon Instinct MI60 Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro M6000 vs Radeon Instinct MI60 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro M6000 vs Radeon Instinct MI60: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro M6000

2015

Why buy it

  • Costs $1,001 less on MSRP ($4,999 MSRP vs $6,000 MSRP).
  • Delivers 21.4% more G3D Mark for each dollar spent, at 2.4 vs 1.9 G3D/$ ($4,999 MSRP vs $6,000 MSRP).
  • 50% more VRAM for high-resolution textures and newer games (12 GB vs 8 GB).
  • Draws 250W instead of 300W, a 50W reduction.

Trade-offs

  • Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
  • 2015 hardware with 12 GB of VRAM already sits in legacy territory for modern games.

Radeon Instinct MI60

2018

Why buy it

  • 12.3% more average FPS across 50 tracked games in our benchmark data.
  • Quadro M6000 is already legacy-tier future-proofing, so Radeon Instinct MI60 is the less risky modern option long term.
  • More future proof: GCN 5.1 (2018−2022) on 7nm with a newer platform for upcoming games.

Trade-offs

  • Less VRAM, with 8 GB vs 12 GB for high-resolution textures and newer games.
  • Older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in newer AAA releases.
  • 20% HIGHER MSRP
    $6,000 MSRPvs$4,999 MSRP
  • Lower G3D Mark per dollar, at 1.9 vs 2.4 G3D/$ ($6,000 MSRP vs $4,999 MSRP).
  • 20% higher power demand at 300W vs 250W.

Quick Answers

Which GPU is faster for gaming right now?
Radeon Instinct MI60 is the faster gaming card right now. In our data, it leads by 12.3% in average FPS across 50 tracked games in our benchmark data. PassMark G3D leans toward Quadro M6000 instead at 11,769 vs 11,638, so for this question the real-game FPS result matters more than the synthetic split.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon Instinct MI60 is the safer long-term pick for 2026 and beyond. The case is simple: the newer upscaling stack, FSR Upscaling / FSR 4 (2025) instead of no meaningful modern upscaling stack, a 7nm process instead of 28nm, and a newer 2018 generation instead of 2015. That makes it the less risky pick as game demands keep moving.
Which GPU is the better buy today?
Quadro M6000 makes the most sense to buy today. It is $1,001 cheaper on MSRP at $4,999 vs $6,000, and it leads G3D-per-dollar by 21.4% (2.4 vs 1.9), which is enough to swing the recommendation its way. If you are mainly targeting 1080p and some 1440p, Quadro M6000 is the easier value choice. If you care more about 1080p and some 1440p headroom, Radeon Instinct MI60 has the stronger long-term case.

Quadro M6000 vs Radeon Instinct MI60 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro M6000

The Quadro M6000 is manufactured by NVIDIA. It was released in March 21 2015. It features the Maxwell 2.0 architecture. The core clock ranges from 988 MHz to 1114 MHz. It has 3072 shading units. The thermal design power (TDP) is 250W. Manufactured using 28 nm process technology. G3D Mark benchmark score: 11,769 points. Launch price was $4,199.99.

AMD

Radeon Instinct MI60

The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.

Graphics Performance

The Quadro M6000 scores 11,769 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 1.1% difference, making them near-identical in rasterization performance. The Quadro M6000 is built on Maxwell 2.0 while the Radeon Instinct MI60 uses GCN 5.1, both on 28 nm vs 7 nm. Shader units: 3,072 (Quadro M6000) vs 4,096 (Radeon Instinct MI60). Raw compute: 6.844 TFLOPS (Quadro M6000) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1114 MHz vs 1800 MHz.

FeatureQuadro M6000Radeon Instinct MI60
G3D Mark Score
11,769+1%
11,638
Architecture
Maxwell 2.0
GCN 5.1
Process Node
28 nm
7 nm
Shading Units
3072
4096+33%
Compute (TFLOPS)
6.844 TFLOPS
14.75 TFLOPS+116%
Boost Clock
1114 MHz
1800 MHz+62%
ROPs
96+50%
64
TMUs
192
256+33%
L1 Cache
1.1 MB+10%
1 MB
L2 Cache
3 MB
4 MB+33%

Advanced Features (DLSS/FSR)

FeatureQuadro M6000Radeon Instinct MI60
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro M6000 has 12 GB of VRAM, while the Radeon Instinct MI60 carries 8 GB. Quadro M6000 gives you 50% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bus width is 384-bit on the Quadro M6000 and 128-bit on the Radeon Instinct MI60. L2 Cache: 3 MB (Quadro M6000) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro M6000Radeon Instinct MI60
VRAM Capacity
12 GB+50%
8 GB
Memory Type
GDDR5
GDDR6
Bus Width
384-bit+200%
128-bit
L2 Cache
3 MB
4 MB+33%
🖥️

Display & API Support

DirectX support: 12/1 (Quadro M6000) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.1 vs 1.3. OpenGL: 4.5 vs 4.5. Maximum simultaneous displays: 4 vs 1.

FeatureQuadro M6000Radeon Instinct MI60
DirectX
12/1
12.1
Vulkan
1.1
1.3+18%
OpenGL
4.5
4.5
Max Displays
4+300%
1
🎬

Media & Encoding

Hardware encoder: NVENC 4.0 (Quadro M6000) vs VCE 4.1 (Radeon Instinct MI60). Decoder: PureVideo HD VP6 vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC (Quadro M6000) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).

FeatureQuadro M6000Radeon Instinct MI60
Encoder
NVENC 4.0
VCE 4.1
Decoder
PureVideo HD VP6
UVD 7.2
Codecs
MPEG-2,H.264,HEVC
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro M6000 draws 250W versus the Radeon Instinct MI60's 300W — a 18.2% difference. The Quadro M6000 is more power-efficient. Recommended PSU: 500W (Quadro M6000) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 267mm vs 267mm, occupying 2 vs 2 slots. Typical load temperature: 80°C vs 85°C.

FeatureQuadro M6000Radeon Instinct MI60
TDP
250W-17%
300W
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
267mm
267mm
Height
112mm
111mm
Slots
2
2
Temp (Load)
80°C-6%
85°C
Perf/Watt
47.1+21%
38.8
💰

Value Analysis

At launch, the Quadro M6000 came in at $4999, while the Radeon Instinct MI60 launched at $6000. On MSRP, Quadro M6000 was 16.7% cheaper ($1001 less). Performance per dollar on MSRP (G3D Mark / MSRP): 2.4 (Quadro M6000) vs 1.9 (Radeon Instinct MI60) — the Quadro M6000 offers 26.3% better value. The newer card here is Radeon Instinct MI60 (2018 vs 2015).

FeatureQuadro M6000Radeon Instinct MI60
MSRP
$4999-17%
$6000
Performance per Dollar
2.4+26%
1.9
Codename
GM200
Vega 20
Release
March 21 2015
November 18 2018
Ranking
#228
#232

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