
Quadro P4000 vs Radeon Instinct MI60

Quadro P4000
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Radeon Instinct MI60
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Performance Spectrum - GPU
About G3D Mark
G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.
Value Upgrade Path
This is the official ChipVERSUS Value Rating, comparing raw performance (G3D Mark) per dollar. Components placed above yours deliver better value for money.
Avg price is the current average price collected from markets across the web.
Performance Per Dollar Quadro P4000
Performance Per Dollar Radeon Instinct MI60
Performance Comparison
About G3D Mark🏆 Chipversus Verdict
⚠️ Generational Difference
The Radeon Instinct MI60 uses modern memory architecture. The Radeon Instinct MI60 likely supports modern features like Ray Tracing, Tensor Cores, and DLSS/FSR upscaling, which act as force multipliers for performance. The Quadro P4000 lacks this hardware feature set, limiting its longevity in modern titles despite any raw power similarities.
🚀 Performance Leadership
The Radeon Instinct MI60 is the superior choice for raw performance. It leads with a 1.8% higher G3D Mark score. This advantage makes it significantly better for higher resolutions (1440p/4K) and graphic-intensive titles compared to the Quadro P4000.
| Insight | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| Performance | ❌Lower raw frame rates (-1.8%) | ✅Leading raw performance (+1.8%) |
| Longevity | 🛑Obsolete Architecture (2017 / Pascal (2016−2021)) | 🛑Obsolete Architecture (2018 / GCN 5.1 (2018−2022)) |
| Ecosystem | Supports FSR Upscaling | Supports FSR Upscaling |
| VRAM | ❌ Less VRAM capacity | ✅ More VRAM (+0%) |
| Efficiency | 💡 Excellent Perf/Watt | ⚡ Higher Power Consumption |
| Case Fit | 📏 Compact / SFF Friendly | Standard Size (267mm) |
💎 Value Proposition
The Quadro P4000 offers a compelling cost-to-performance ratio. Priced at $290 versus $600 for the Radeon Instinct MI60, it costs 52% less. While it maintains competitive performance, this results in a 103.2% higher cost efficiency score.
| Insight | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| Cost Efficiency | ✅Better overall value (+103.2%) | ❌Lower cost efficiency |
| Upfront Cost | ✅More affordable ($290) | ⚠️Higher upfront cost ($600) |
Performance Check
Real-world benchmarks and performance projections based on comprehensive hardware analysis and comparative metrics. Values represent expected performance on High/Ultra settings at 1080p, 1440p, and 4K. Modeled using a Ryzen 7 7800X3D reference profile to minimize specific CPU bottlenecks.
Note: Performance behavior can vary per game. Specific architectures may perform better or worse depending on game engine optimizations and API implementation.
Technical Specifications
Side-by-side comparison of Quadro P4000 and Radeon Instinct MI60

Quadro P4000
The Quadro P4000 is manufactured by NVIDIA. It was released in February 6 2017. It features the Pascal architecture. The core clock ranges from 1202 MHz to 1480 MHz. It has 1792 shading units. The thermal design power (TDP) is 105W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 11,431 points. Launch price was $815.

Radeon Instinct MI60
The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.
Graphics Performance
The Quadro P4000 scores 11,431 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 1.8% difference, making them near-identical in rasterization performance. The Quadro P4000 is built on Pascal while the Radeon Instinct MI60 uses GCN 5.1, both on 16 nm vs 7 nm. Shader units: 1,792 (Quadro P4000) vs 4,096 (Radeon Instinct MI60). Raw compute: 5.304 TFLOPS (Quadro P4000) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1480 MHz vs 1800 MHz.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| G3D Mark Score | 11,431 | 11,638+2% |
| Architecture | Pascal | GCN 5.1 |
| Process Node | 16 nm | 7 nm |
| Shading Units | 1792 | 4096+129% |
| Compute (TFLOPS) | 5.304 TFLOPS | 14.75 TFLOPS+178% |
| Boost Clock | 1480 MHz | 1800 MHz+22% |
| ROPs | 64 | 64 |
| TMUs | 112 | 256+129% |
| L1 Cache | 0.66 MB | 1 MB+52% |
| L2 Cache | 2 MB | 4 MB+100% |
Advanced Features (DLSS/FSR)
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| Upscaling Tech | FSR 1.0 (Software) | FSR 1.0 (Software) |
| Frame Generation | Not Supported | Not Supported |
| Ray Reconstruction | No | No |
| Low Latency | Standard | AMD Anti-Lag |
Video Memory (VRAM)
Both cards feature 8 GB of GDDR6. Bus width: 256-bit vs 128-bit. L2 Cache: 2 MB (Quadro P4000) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| VRAM Capacity | 8 GB | 8 GB |
| Memory Type | GDDR6 | GDDR6 |
| Bus Width | 256-bit+100% | 128-bit |
| L2 Cache | 2 MB | 4 MB+100% |
Display & API Support
DirectX support: 12.0 (Quadro P4000) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.0 vs 1.3. OpenGL: 4.5 vs 4.5. Maximum simultaneous displays: 4 vs 1.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| DirectX | 12.0 | 12.1 |
| Vulkan | 1.0 | 1.3+30% |
| OpenGL | 4.5 | 4.5 |
| Max Displays | 4+300% | 1 |
Media & Encoding
Hardware encoder: 6th Gen NVENC (Quadro P4000) vs VCE 4.1 (Radeon Instinct MI60). Decoder: PureVideo HD VP8 vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC (Quadro P4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| Encoder | 6th Gen NVENC | VCE 4.1 |
| Decoder | PureVideo HD VP8 | UVD 7.2 |
| Codecs | MPEG-2,H.264,HEVC | MPEG-2,H.264,HEVC,VP9 |
Power & Dimensions
The Quadro P4000 draws 105W versus the Radeon Instinct MI60's 300W — a 96.3% difference. The Quadro P4000 is more power-efficient. Recommended PSU: 500W (Quadro P4000) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 241mm vs 267mm, occupying 1 vs 2 slots. Typical load temperature: 80°C vs 85°C.
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| TDP | 105W-65% | 300W |
| Recommended PSU | 500W | 500W |
| Power Connector | PCIe-powered | PCIe-powered |
| Length | 241mm | 267mm |
| Height | 111mm | 111mm |
| Slots | 1-50% | 2 |
| Temp (Load) | 80°C-6% | 85°C |
| Perf/Watt | 108.9+181% | 38.8 |
Value Analysis
The Quadro P4000 launched at $815 MSRP and currently averages $290, while the Radeon Instinct MI60 launched at $6000 and now averages $600. The Quadro P4000 costs 51.7% less ($310 savings) at current market prices. Performance per dollar (G3D Mark / price): 39.4 (Quadro P4000) vs 19.4 (Radeon Instinct MI60) — the Quadro P4000 offers 103.1% better value. The Radeon Instinct MI60 is the newer GPU (2018 vs 2017).
| Feature | Quadro P4000 | Radeon Instinct MI60 |
|---|---|---|
| MSRP | $815-86% | $6000 |
| Avg Price (30d) | $290-52% | $600 |
| Performance per Dollar | 39.4+103% | 19.4 |
| Codename | GP104 | Vega 20 |
| Release | February 6 2017 | November 18 2018 |
| Ranking | #239 | #232 |
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