Quadro P4000 vs Radeon Instinct MI60

NVIDIA

Quadro P4000

2017Core: 1202 MHzBoost: 1480 MHz
Similar parts
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VS
AMD

Radeon Instinct MI60

2018Core: 1200 MHzBoost: 1800 MHz
Similar parts
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Quadro P4000 vs Radeon Instinct MI60 Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro P4000 vs Radeon Instinct MI60 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro P4000 vs Radeon Instinct MI60: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro P4000

2017

Why buy it

  • Costs $5,185 less on MSRP ($815 MSRP vs $6,000 MSRP).
  • Delivers 623.1% more G3D Mark for each dollar spent, at 14.0 vs 1.9 G3D/$ ($815 MSRP vs $6,000 MSRP).
  • Draws 105W instead of 300W, a 195W reduction.
  • Measures 241mm instead of 267mm, a 26mm shorter card that is more SFF-friendly.

Trade-offs

  • Lower average FPS than Radeon Instinct MI60 across 50 tracked games in our benchmark data.
  • 2017 hardware with 8 GB of VRAM already sits in legacy territory for modern games.

Radeon Instinct MI60

2018

Why buy it

  • 25.2% more average FPS across 50 tracked games in our benchmark data.
  • Quadro P4000 is already legacy-tier future-proofing, so Radeon Instinct MI60 is the less risky modern option long term.
  • More future proof: GCN 5.1 (2018−2022) on 7nm with a newer platform for upcoming games.

Trade-offs

  • Older hardware, 8 GB of VRAM, and weaker feature support mean it will age faster in newer AAA releases.
  • 636.2% HIGHER MSRP
    $6,000 MSRPvs$815 MSRP
  • Lower G3D Mark per dollar, at 1.9 vs 14.0 G3D/$ ($6,000 MSRP vs $815 MSRP).
  • 185.7% higher power demand at 300W vs 105W.
  • 10.8% longer card at 267mm vs 241mm.

Quick Answers

Which GPU is faster for gaming right now?
Radeon Instinct MI60 is the faster gaming card right now. In our data, it leads by 25.2% in average FPS across 50 tracked games in our benchmark data and by 1.8% in PassMark G3D (11,638 vs 11,431), so the answer here is pretty clean.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon Instinct MI60 is the safer long-term pick for 2026 and beyond. The case is simple: the newer upscaling stack, FSR Upscaling / FSR 4 (2025) instead of no meaningful modern upscaling stack, a 7nm process instead of 16nm, and a newer 2018 generation instead of 2017. That makes it the less risky pick as game demands keep moving.
Which GPU is the better buy today?
Quadro P4000 makes the most sense to buy today. It is $5,185 cheaper on MSRP at $815 vs $6,000, and it leads G3D-per-dollar by 623.1% (14.0 vs 1.9), which is enough to swing the recommendation its way. If you are mainly targeting 1080p and some 1440p, Quadro P4000 is the easier value choice. If you care more about 1080p and some 1440p headroom, Radeon Instinct MI60 has the stronger long-term case.

Quadro P4000 vs Radeon Instinct MI60 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro P4000

The Quadro P4000 is manufactured by NVIDIA. It was released in February 6 2017. It features the Pascal architecture. The core clock ranges from 1202 MHz to 1480 MHz. It has 1792 shading units. The thermal design power (TDP) is 105W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 11,431 points. Launch price was $815.

AMD

Radeon Instinct MI60

The Radeon Instinct MI60 is manufactured by AMD. It was released in November 18 2018. It features the GCN 5.1 architecture. The core clock ranges from 1200 MHz to 1800 MHz. It has 4096 shading units. The thermal design power (TDP) is 300W. Manufactured using 7 nm process technology. G3D Mark benchmark score: 11,638 points.

Graphics Performance

The Quadro P4000 scores 11,431 and the Radeon Instinct MI60 reaches 11,638 in the G3D Mark benchmark — just a 1.8% difference, making them near-identical in rasterization performance. The Quadro P4000 is built on Pascal while the Radeon Instinct MI60 uses GCN 5.1, both on 16 nm vs 7 nm. Shader units: 1,792 (Quadro P4000) vs 4,096 (Radeon Instinct MI60). Raw compute: 5.304 TFLOPS (Quadro P4000) vs 14.75 TFLOPS (Radeon Instinct MI60). Boost clocks: 1480 MHz vs 1800 MHz.

FeatureQuadro P4000Radeon Instinct MI60
G3D Mark Score
11,431
11,638+2%
Architecture
Pascal
GCN 5.1
Process Node
16 nm
7 nm
Shading Units
1792
4096+129%
Compute (TFLOPS)
5.304 TFLOPS
14.75 TFLOPS+178%
Boost Clock
1480 MHz
1800 MHz+22%
ROPs
64
64
TMUs
112
256+129%
L1 Cache
0.66 MB
1 MB+52%
L2 Cache
2 MB
4 MB+100%

Advanced Features (DLSS/FSR)

FeatureQuadro P4000Radeon Instinct MI60
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards ship with 8 GB of GDDR6. Memory bus width is 256-bit on the Quadro P4000 and 128-bit on the Radeon Instinct MI60. L2 Cache: 2 MB (Quadro P4000) vs 4 MB (Radeon Instinct MI60) — the Radeon Instinct MI60 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro P4000Radeon Instinct MI60
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Bus Width
256-bit+100%
128-bit
L2 Cache
2 MB
4 MB+100%
🖥️

Display & API Support

DirectX support: 12.0 (Quadro P4000) vs 12.1 (Radeon Instinct MI60). Vulkan: 1.0 vs 1.3. OpenGL: 4.5 vs 4.5. Maximum simultaneous displays: 4 vs 1.

FeatureQuadro P4000Radeon Instinct MI60
DirectX
12.0
12.1
Vulkan
1.0
1.3+30%
OpenGL
4.5
4.5
Max Displays
4+300%
1
🎬

Media & Encoding

Hardware encoder: 6th Gen NVENC (Quadro P4000) vs VCE 4.1 (Radeon Instinct MI60). Decoder: PureVideo HD VP8 vs UVD 7.2. Supported codecs: MPEG-2,H.264,HEVC (Quadro P4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon Instinct MI60).

FeatureQuadro P4000Radeon Instinct MI60
Encoder
6th Gen NVENC
VCE 4.1
Decoder
PureVideo HD VP8
UVD 7.2
Codecs
MPEG-2,H.264,HEVC
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro P4000 draws 105W versus the Radeon Instinct MI60's 300W — a 96.3% difference. The Quadro P4000 is more power-efficient. Recommended PSU: 500W (Quadro P4000) vs 500W (Radeon Instinct MI60). Power connectors: PCIe-powered vs PCIe-powered. Card length: 241mm vs 267mm, occupying 1 vs 2 slots. Typical load temperature: 80°C vs 85°C.

FeatureQuadro P4000Radeon Instinct MI60
TDP
105W-65%
300W
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
241mm
267mm
Height
111mm
111mm
Slots
1-50%
2
Temp (Load)
80°C-6%
85°C
Perf/Watt
108.9+181%
38.8
💰

Value Analysis

At launch, the Quadro P4000 came in at $815, while the Radeon Instinct MI60 launched at $6000. On MSRP, Quadro P4000 was 86.4% cheaper ($5185 less). Performance per dollar on MSRP (G3D Mark / MSRP): 14.0 (Quadro P4000) vs 1.9 (Radeon Instinct MI60) — the Quadro P4000 offers 636.8% better value. The newer card here is Radeon Instinct MI60 (2018 vs 2017).

FeatureQuadro P4000Radeon Instinct MI60
MSRP
$815-86%
$6000
Performance per Dollar
14.0+637%
1.9
Codename
GP104
Vega 20
Release
February 6 2017
November 18 2018
Ranking
#239
#232

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