Radeon Pro Vega 64 vs Radeon RX 6600S

AMD

Radeon Pro Vega 64

2017Core: 1250 MHzBoost: 1350 MHz
VS
AMD

Radeon RX 6600S

2022Core: 1700 MHzBoost: 2000 MHz
Similar parts
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Radeon Pro Vega 64 vs Radeon RX 6600S Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Radeon Pro Vega 64 vs Radeon RX 6600S FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Radeon Pro Vega 64 vs Radeon RX 6600S: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Radeon Pro Vega 64

2017

Why buy it

  • 2.1% more average FPS across 50 tracked games in our benchmark data.

Trade-offs

  • Less VRAM, with Unknown vs 4 GB for high-resolution textures and newer games.
  • No equivalent frame-generation stack like FSR Frame Generation + AFMF (2023).
  • 2017 hardware with Unknown of VRAM is already well past its comfortable zone for modern gaming, so it is hard to recommend now.
  • 49.8% HIGHER MSRP
    $599 MSRPvs$400 MSRP
  • Lower G3D Mark per dollar, at 21.5 vs 32.5 G3D/$ ($599 MSRP vs $400 MSRP).

Radeon RX 6600S

2022

Why buy it

  • Costs $199 less on MSRP ($400 MSRP vs $599 MSRP).
  • Delivers 51.2% more G3D Mark for each dollar spent, at 32.5 vs 21.5 G3D/$ ($400 MSRP vs $599 MSRP).
  • Access to a newer frame-generation stack with FSR Frame Generation + AFMF (2023).
  • 100+% more VRAM for high-resolution textures and newer games (4 GB vs Unknown).
  • Better long-term bet: RDNA 2.0 (2020−2025) on 7nm gives it a newer hardware base for upcoming games.

Trade-offs

  • Lower average FPS than Radeon Pro Vega 64 across 50 tracked games in our benchmark data.

Quick Answers

Which GPU is faster for gaming right now?
Radeon Pro Vega 64 is the faster gaming card right now. In our data, it leads by 2.1% in average FPS across 50 tracked games in our benchmark data. PassMark G3D leans toward Radeon RX 6600S instead at 13,016 vs 12,891, so for this question the real-game FPS result matters more than the synthetic split.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon RX 6600S is the safer long-term pick for 2026 and beyond. The case is simple: 4 GB vs Unknown of VRAM, native frame generation with FSR Frame Generation + AFMF (2023), while Radeon Pro Vega 64 has no comparable frame-generation support, a 7nm process instead of 14nm, and 28 vs 0 ray-tracing units. That gives it more room for heavier textures and higher settings over time.
Which GPU is the better buy today?
Radeon RX 6600S makes the most sense to buy today. It is $199 cheaper on MSRP at $400 vs $599, and it leads G3D-per-dollar by 51.2% (32.5 vs 21.5), which is enough to swing the recommendation its way. Radeon Pro Vega 64 still makes more sense if max raw gaming performance matters more than value.

Radeon Pro Vega 64 vs Radeon RX 6600S Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

AMD

Radeon Pro Vega 64

The Radeon Pro Vega 64 is manufactured by AMD. It was released in June 27 2017. It features the GCN 5.0 architecture. The core clock ranges from 1250 MHz to 1350 MHz. It has 4096 shading units. The thermal design power (TDP) is 250W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 12,891 points.

AMD

Radeon RX 6600S

The Radeon RX 6600S is manufactured by AMD. It was released in January 4 2022. It features the RDNA 2.0 architecture. The core clock ranges from 1700 MHz to 2000 MHz. It has 1792 shading units. The thermal design power (TDP) is 80W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 13,016 points.

Graphics Performance

The Radeon Pro Vega 64 scores 12,891 and the Radeon RX 6600S reaches 13,016 in the G3D Mark benchmark — just a 1% difference, making them near-identical in rasterization performance. The Radeon Pro Vega 64 is built on GCN 5.0 while the Radeon RX 6600S uses RDNA 2.0, both on 14 nm vs 7 nm. Shader units: 4,096 (Radeon Pro Vega 64) vs 1,792 (Radeon RX 6600S). Raw compute: 11.06 TFLOPS (Radeon Pro Vega 64) vs 7.168 TFLOPS (Radeon RX 6600S). Boost clocks: 1350 MHz vs 2000 MHz.

FeatureRadeon Pro Vega 64Radeon RX 6600S
G3D Mark Score
12,891
13,016
Architecture
GCN 5.0
RDNA 2.0
Process Node
14 nm
7 nm
Shading Units
4096+129%
1792
Compute (TFLOPS)
11.06 TFLOPS+54%
7.168 TFLOPS
Boost Clock
1350 MHz
2000 MHz+48%
ROPs
64
64
TMUs
256+129%
112
L1 Cache
1 MB+100%
0.5 MB
L2 Cache
4 MB+100%
2 MB
Frame Generation
FSR upscaling
FSR 3 + AFMF

Advanced Features (DLSS/FSR)

The clearest feature edge for the Radeon RX 6600S is support for FSR Frame Generation + AFMF. In games that support it, that can smooth out motion and lift perceived FPS. The Radeon Pro Vega 64 does not have comparable native support in the same tier.

FeatureRadeon Pro Vega 64Radeon RX 6600S
Upscaling Tech
FSR Upscaling / FSR 4
FSR 3
Frame Generation
Not Supported
FSR Frame Generation + AFMF
Ray Reconstruction
No
No
Low Latency
AMD Anti-Lag
AMD Anti-Lag
💾

Video Memory (VRAM)

The Radeon Pro Vega 64 has 0 MB of VRAM, while the Radeon RX 6600S carries 4 GB. Radeon RX 6600S gives you 100+% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bus width is 128-bit on the Radeon Pro Vega 64 and 128-bit on the Radeon RX 6600S. L2 Cache: 4 MB (Radeon Pro Vega 64) vs 2 MB (Radeon RX 6600S) — the Radeon Pro Vega 64 has significantly larger on-die cache to reduce VRAM reliance.

FeatureRadeon Pro Vega 64Radeon RX 6600S
VRAM Capacity
Shared System RAM
4 GB
Memory Type
GDDR6
GDDR6
Bus Width
128-bit
128-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12.1 (Radeon Pro Vega 64) vs 12_2 (Radeon RX 6600S). Vulkan: 1.1 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 0.

FeatureRadeon Pro Vega 64Radeon RX 6600S
DirectX
12.1
12_2
Vulkan
1.1
1.4+27%
OpenGL
4.6
4.6
Max Displays
4
0
🎬

Media & Encoding

Hardware encoder: VCE 4.0 (Radeon Pro Vega 64) vs VCN 3.0 (Radeon RX 6600S). Decoder: UVD 7.0 vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Radeon Pro Vega 64) vs H.264,H.265/HEVC (Radeon RX 6600S).

FeatureRadeon Pro Vega 64Radeon RX 6600S
Encoder
VCE 4.0
VCN 3.0
Decoder
UVD 7.0
VCN 3.0
Codecs
MPEG-2,H.264,HEVC,VP9
H.264,H.265/HEVC
🔌

Power & Dimensions

The Radeon Pro Vega 64 draws 250W versus the Radeon RX 6600S's 80W — a 103% difference. The Radeon RX 6600S is more power-efficient. Recommended PSU: 1W (Radeon Pro Vega 64) vs 500W (Radeon RX 6600S). Power connectors: Integrated vs Mobile. Card length: 267mm vs 1mm, occupying 2 vs 0 slots.

FeatureRadeon Pro Vega 64Radeon RX 6600S
TDP
250W
80W-68%
Recommended PSU
1W-100%
500W
Power Connector
Integrated
Mobile
Length
267mm
1mm
Height
111mm
Slots
2
0-100%
Temp (Load)
85°C
Perf/Watt
51.6
162.7+215%
💰

Value Analysis

At launch, the Radeon Pro Vega 64 came in at $599, while the Radeon RX 6600S launched at $400. On MSRP, Radeon RX 6600S was 33.2% cheaper ($199 less). Performance per dollar on MSRP (G3D Mark / MSRP): 21.5 (Radeon Pro Vega 64) vs 32.5 (Radeon RX 6600S) — the Radeon RX 6600S offers 51.2% better value. The newer card here is Radeon RX 6600S (2022 vs 2017).

FeatureRadeon Pro Vega 64Radeon RX 6600S
MSRP
$599
$400-33%
Performance per Dollar
21.5
32.5+51%
Codename
Vega 10
Navi 23
Release
June 27 2017
January 4 2022
Ranking
#202
#200

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