Ryzen Threadripper PRO 3995WX vs Xeon 6780E

AMD

Ryzen Threadripper PRO 3995WX

64 Cores128 Thrd280 WWMax: 4.2 GHz2020
Threadripper Pro family
Β·Β·
VS
Intel

Xeon 6780E

144 Cores144 Thrd330 WWMax: 3 GHz2024
Similar parts

Ryzen Threadripper PRO 3995WX vs Xeon 6780E Performance Spectrum

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Ryzen Threadripper PRO 3995WX vs Xeon 6780E FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

Ryzen Threadripper PRO 3995WX vs Xeon 6780E: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

Ryzen Threadripper PRO 3995WX

2020

Why buy it

  • βœ…Better for gaming: +13.3% higher average FPS across 50 shared CPU benchmark tests.
  • βœ…+137% larger total L3 cache (256 MB vs 108 MB).
  • βœ…Costs $5,861 less on MSRP ($5,489 MSRP vs $11,350 MSRP).
  • βœ…Delivers 98.4% more PassMark for each dollar spent, at 15.2 vs 7.6 PassMark/$ ($5,489 MSRP vs $11,350 MSRP).
  • βœ…Draws 280W instead of 330W, a 50W reduction.

Trade-offs

  • ❌Lower PassMark (83,235 vs 86,734).
  • ❌Older platform position on sWRX8 with DDR4, while Xeon 6780E moves to LGA4710 and DDR5.

Xeon 6780E

2024

Why buy it

  • βœ…+4.2% higher PassMark.
  • βœ…Newer platform on LGA4710 with DDR5 support instead of sWRX8 and DDR4.

Trade-offs

  • ❌Worse for gaming: lower average FPS than Ryzen Threadripper PRO 3995WX across 50 shared CPU benchmark tests.
  • ❌Smaller total L3 cache (108 MB vs 256 MB).
  • ❌Lower PassMark per dollar, at 7.6 vs 15.2 PassMark/$ ($11,350 MSRP vs $5,489 MSRP).
  • ❌17.9% higher power demand at 330W vs 280W.

Quick Answers

So, is Ryzen Threadripper PRO 3995WX better than Xeon 6780E?
It depends on what you want from the system. For gaming, Ryzen Threadripper PRO 3995WX is ahead with a 13.3% average FPS lead across 50 shared CPU game tests in our data. For rendering, compiling, streaming, and heavier multitasking, Xeon 6780E pulls ahead with 4.2% better PassMark. Ryzen Threadripper PRO 3995WX also has the bigger cache pool with 137% larger total L3 cache (256 MB vs 108 MB).
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, Xeon 6780E is the stronger fit. You are getting 4.2% better PassMark, backed by 144 cores and 144 threads.
Which one is the smarter buy today, not just the cheaper CPU?
Ryzen Threadripper PRO 3995WX is the better buy right now. Ryzen Threadripper PRO 3995WX comes in $5,861 cheaper on MSRP at $5,489 MSRP versus $11,350 MSRP, and it still gives you a 13.3% average FPS lead across 50 shared CPU game tests in our data. The compromise is that Xeon 6780E is still stronger for heavier multi-core work with 4.2% better PassMark. It is also 98.4% better value on MSRP (15.2 vs 7.6 PassMark/$), so you are getting the faster CPU without taking a value hit on paper.
Which one is more future-proof for 2026 and beyond?
Xeon 6780E makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2024 vs 2020), a healthier platform with LGA4710 and DDR5 instead of sWRX8, and more multi-core headroom with 144 cores / 144 threads instead of 64/128. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

Ryzen Threadripper PRO 3995WX vs Xeon 6780E Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

AMD

Ryzen Threadripper PRO 3995WX

The Ryzen Threadripper PRO 3995WX is manufactured by AMD. It was released in 14 July 2020 (5 years ago). It is based on the Matisse (2019βˆ’2020) architecture. It features 64 cores and 128 threads. Base frequency is 2.7 GHz, with boost up to 4.2 GHz. L3 cache: 256 MB. L2 cache: 512K (per core). Built on 7 nm, 12 nm process technology. Socket: sWRX8. Thermal design power (TDP): 280 Watt. Memory support: DDR4-3200. Passmark benchmark score: 83,235 points. Launch price was $5,500.

Intel

Xeon 6780E

The Xeon 6780E is manufactured by Intel. It was released in 3 June 2024 (1 year ago). It is based on the Sierra Forest (2024) architecture. It features 144 cores and 144 threads. Base frequency is 2.2 GHz, with boost up to 3 GHz. L3 cache: 108 MB (total). L2 cache: 4 MB (per module). Built on Intel 3 nm process technology. Socket: LGA4710. Thermal design power (TDP): 330 Watt. Memory support: DDR5-6400. Passmark benchmark score: 86,734 points. Launch price was $11,350.

⚑

Processing Power

The Ryzen Threadripper PRO 3995WX packs 64 cores / 128 threads, while the Xeon 6780E offers 144 cores / 144 threads β€” the Xeon 6780E has 80 more cores. Boost clocks reach 4.2 GHz on the Ryzen Threadripper PRO 3995WX versus 3 GHz on the Xeon 6780E β€” a 33.3% clock advantage for the Ryzen Threadripper PRO 3995WX (base: 2.7 GHz vs 2.2 GHz). The Ryzen Threadripper PRO 3995WX uses the Matisse (2019βˆ’2020) architecture (7 nm, 12 nm), while the Xeon 6780E uses Sierra Forest (2024) (Intel 3 nm). In PassMark, the Ryzen Threadripper PRO 3995WX scores 83,235 against the Xeon 6780E's 86,734 β€” a 4.1% lead for the Xeon 6780E. L3 cache: 256 MB on the Ryzen Threadripper PRO 3995WX vs 108 MB (total) on the Xeon 6780E.

FeatureRyzen Threadripper PRO 3995WXXeon 6780E
Cores / Threads
64 / 128
144 / 144+125%
Boost Clock
4.2 GHz+40%
3 GHz
Base Clock
2.7 GHz+23%
2.2 GHz
L3 Cache
256 MB+137%
108 MB (total)
L2 Cache
512K (per core)+12700%
4 MB (per module)
Process
7 nm, 12 nm
Intel 3 nm-57%
Architecture
Matisse (2019βˆ’2020)
Sierra Forest (2024)
PassMark
83,235
86,734+4%
Cinebench R23 Multi
64,355
β€”
Geekbench 6 Single
1,266
β€”
Geekbench 6 Multi
20,256
β€”
🧠

Memory & Platform

The Ryzen Threadripper PRO 3995WX uses the sWRX8 socket (PCIe 4.0), while the Xeon 6780E uses LGA4710 (PCIe 4.0) β€” making them incompatible on the same motherboard. Maximum memory speed reaches DDR4-3200 on the Ryzen Threadripper PRO 3995WX versus DDR5-6400 on the Xeon 6780E β€” the Xeon 6780E supports 100% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon 6780E supports up to 4 TB of RAM compared to 2048 GB β€” 100% more capacity for professional workloads. Both feature 8-channel memory with ECC support. PCIe lanes: 128 (Ryzen Threadripper PRO 3995WX) vs 88 (Xeon 6780E) β€” the Ryzen Threadripper PRO 3995WX offers 40 more lanes for additional GPUs or NVMe drives.

FeatureRyzen Threadripper PRO 3995WXXeon 6780E
Socket
sWRX8
LGA4710
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
DDR4-3200
DDR5-6400+100%
Max RAM Capacity
2048 GB
4 TB+100%
RAM Channels
8
8
ECC Support
Yes
Yes
PCIe Lanes
128+45%
88
πŸ”§

Advanced Features

Virtualization support: true (Ryzen Threadripper PRO 3995WX) vs VT-x, VT-d, VT-x EPT (Xeon 6780E). Primary use case: Xeon 6780E targets Cloud Native Compute. Direct competitor: Ryzen Threadripper PRO 3995WX rivals Xeon Platinum 8280; Xeon 6780E rivals EPYC 9754.

FeatureRyzen Threadripper PRO 3995WXXeon 6780E
Integrated GPU
No
No
IGPU Model
None
β€”
Unlocked
Yes
β€”
AVX-512
No
β€”
Virtualization
true
VT-x, VT-d, VT-x EPT
Target Use
β€”
Cloud Native Compute
πŸ’°

Value Analysis

At launch, the Ryzen Threadripper PRO 3995WX was priced at $5489, while the Xeon 6780E came in at $11350. On launch pricing ($5489 vs $11350), Ryzen Threadripper PRO 3995WX was $5861 cheaper. In terms of value on MSRP (PassMark points per dollar), the Ryzen Threadripper PRO 3995WX delivers 15.2 pts/$ vs 7.6 pts/$ for the Xeon 6780E β€” making the Ryzen Threadripper PRO 3995WX the 66% better value option.

FeatureRyzen Threadripper PRO 3995WXXeon 6780E
MSRP
$5489-52%
$11350
Performance per Dollar
15.2+100%
7.6
Release Date
2020
2024

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