EPYC 4345P vs EPYC 7601

AMD

EPYC 4345P

8 Cores16 Thrd65 WWMax: 5.5 GHz2025
EPYC family
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VS
AMD

EPYC 7601

32 Cores64 Thrd180 WWMax: 3.2 GHz2017
EPYC family
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EPYC 4345P vs EPYC 7601 Performance Spectrum

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

EPYC 4345P vs EPYC 7601 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

EPYC 4345P vs EPYC 7601: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

EPYC 4345P

2025

Why buy it

  • Better for gaming: +21.0% higher average FPS across 50 shared CPU benchmark tests.
  • Draws 65W instead of 180W, a 115W reduction.
  • Newer platform on AM5 with DDR5 support instead of TR4 and DDR4.
  • Integrated graphics onboard with AMD Radeon Graphics, while EPYC 7601 needs a discrete GPU.

Trade-offs

  • Smaller total L3 cache (32 MB vs 64 MB).
  • Launch MSRP is still $329 MSRP, while EPYC 7601 mostly shows up through inconsistent older-market listings.

EPYC 7601

2017

Why buy it

  • +100% larger total L3 cache (64 MB vs 32 MB).
  • 357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4345P across 50 shared CPU benchmark tests.
  • Lower PassMark (35,059 vs 36,006).
  • 176.9% higher power demand at 180W vs 65W.
  • Older platform position on TR4 with DDR4, while EPYC 4345P moves to AM5 and DDR5.
  • No integrated graphics, while EPYC 4345P can still boot and troubleshoot without a discrete GPU.

Quick Answers

So, is EPYC 4345P better than EPYC 7601?
Yes. EPYC 4345P is the better all-around CPU here. It gives you a 21.0% average FPS lead across 50 shared CPU game tests in our data, 2.7% better PassMark, and the stronger long-term platform, which is enough to make it the stronger overall pick.
Which one is better for gaming?
If gaming is the priority, EPYC 4345P is the better pick. According to our tests, it delivers 21.0% more average FPS across 50 shared CPU game tests.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 4345P is the stronger fit. You are getting 2.7% better PassMark, backed by 8 cores and 16 threads.
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4345P is the better buy right now. EPYC 4345P comes in at an unclear MSRP at $329 MSRP versus unclear MSRP, and it still gives you a 21.0% average FPS lead across 50 shared CPU game tests in our data. It is also 100.0% better value on MSRP (109.4 vs 0.0 PassMark/$), so you are getting the faster CPU without taking a value hit on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4345P makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2017), a healthier platform with AM5 and DDR5 instead of TR4, more multi-core headroom with 8 cores / 16 threads instead of 32/64, and AVX-512 support for heavier modern compute workloads. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

EPYC 4345P vs EPYC 7601 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

AMD

EPYC 4345P

The EPYC 4345P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 8 cores and 16 threads. Base frequency is 3.8 GHz, with boost up to 5.5 GHz. L3 cache: 32 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 36,006 points. Launch price was $329.

AMD

EPYC 7601

The EPYC 7601 is manufactured by AMD. It was released in 29 June 2017 (8 years ago). It is based on the Naples (2017−2018) architecture. It features 32 cores and 64 threads. Base frequency is 2.2 GHz, with boost up to 3.2 GHz. L3 cache: 64 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: TR4. Thermal design power (TDP): 180 Watt. Memory support: DDR4 Eight-channel. Passmark benchmark score: 35,059 points. Launch price was $4,200.

Processing Power

The EPYC 4345P packs 8 cores / 16 threads, while the EPYC 7601 offers 32 cores / 64 threads — the EPYC 7601 has 24 more cores. Boost clocks reach 5.5 GHz on the EPYC 4345P versus 3.2 GHz on the EPYC 7601 — a 52.9% clock advantage for the EPYC 4345P (base: 3.8 GHz vs 2.2 GHz). The EPYC 4345P uses the Grado (2025) architecture (4 nm), while the EPYC 7601 uses Naples (2017−2018) (14 nm). In PassMark, the EPYC 4345P scores 36,006 against the EPYC 7601's 35,059 — a 2.7% lead for the EPYC 4345P. L3 cache: 32 MB (total) on the EPYC 4345P vs 64 MB (total) on the EPYC 7601.

FeatureEPYC 4345PEPYC 7601
Cores / Threads
8 / 16
32 / 64+300%
Boost Clock
5.5 GHz+72%
3.2 GHz
Base Clock
3.8 GHz+73%
2.2 GHz
L3 Cache
32 MB (total)
64 MB (total)+100%
L2 Cache
1 MB (per core)
512K (per core)+51100%
Process
4 nm-71%
14 nm
Architecture
Grado (2025)
Naples (2017−2018)
PassMark
36,006+3%
35,059
🧠

Memory & Platform

The EPYC 4345P uses the AM5 socket (PCIe 4.0), while the EPYC 7601 uses TR4 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4345P versus 2666 on the EPYC 7601 — the EPYC 4345P supports 110.1% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7601 supports up to 2048 of RAM compared to 128 1500% more capacity for professional workloads. Memory channels: 2 (EPYC 4345P) vs 8 (EPYC 7601). PCIe lanes: 28 (EPYC 4345P) vs 128 (EPYC 7601) — the EPYC 7601 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4345P) and SP3 (EPYC 7601).

FeatureEPYC 4345PEPYC 7601
Socket
AM5
TR4
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
5600+110%
2666
Max RAM Capacity
128
2048+1500%
RAM Channels
2
8+300%
ECC Support
Yes
Yes
PCIe Lanes
28
128+357%
🔧

Advanced Features

Neither processor supports overclocking. Only the EPYC 4345P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: AMD-V, IOMMU (EPYC 4345P) vs AMD-V, SVM (EPYC 7601). The EPYC 4345P includes integrated graphics (AMD Radeon Graphics), while the EPYC 7601 requires a dedicated GPU. Direct competitor: EPYC 4345P rivals Xeon E-2488; EPYC 7601 rivals Xeon Platinum 8180.

FeatureEPYC 4345PEPYC 7601
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
None
Unlocked
No
No
AVX-512
Yes
No
Virtualization
AMD-V, IOMMU
AMD-V, SVM