PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Head-to-Head Verdict, Benchmarks, Value & Long-Term Outlook

This comparison brings together gaming FPS, productivity performance, platform differences, power efficiency, pricing context, and upgrade path so you can see which CPU actually makes more sense.

EPYC 4345P

2025

Why buy it

✅Better for gaming: +59.4% higher average FPS across 4 shared CPU benchmark tests.
✅Draws 65W instead of 180W, a 115W reduction.
✅Newer platform on AM5 with DDR5 support instead of TR4 and DDR4.
✅Integrated graphics onboard with AMD Radeon Graphics, while EPYC 7601 needs a discrete GPU.

Trade-offs

❌Smaller total L3 cache (32 MB vs 64 MB).
❌Launch MSRP is still $329 MSRP, while EPYC 7601 mostly shows up through inconsistent older-market listings.

EPYC 7601

2017

Why buy it

✅+100% larger total L3 cache (64 MB vs 32 MB).
✅357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 4345P across 4 shared CPU benchmark tests.
❌Lower PassMark (35,059 vs 36,006).
❌176.9% higher power demand at 180W vs 65W.
❌Older platform position on TR4 with DDR4, while EPYC 4345P moves to AM5 and DDR5.
❌No integrated graphics, while EPYC 4345P can still boot and troubleshoot without a discrete GPU.

EPYC 4345P

2025

EPYC 7601

2017

Why buy it

✅Better for gaming: +59.4% higher average FPS across 4 shared CPU benchmark tests.
✅Draws 65W instead of 180W, a 115W reduction.
✅Newer platform on AM5 with DDR5 support instead of TR4 and DDR4.
✅Integrated graphics onboard with AMD Radeon Graphics, while EPYC 7601 needs a discrete GPU.

Why buy it

✅+100% larger total L3 cache (64 MB vs 32 MB).
✅357.1% more PCIe lanes (128 vs 28) for storage and expansion-heavy builds.

Trade-offs

❌Smaller total L3 cache (32 MB vs 64 MB).
❌Launch MSRP is still $329 MSRP, while EPYC 7601 mostly shows up through inconsistent older-market listings.

Trade-offs

❌Worse for gaming: lower average FPS than EPYC 4345P across 4 shared CPU benchmark tests.
❌Lower PassMark (35,059 vs 36,006).
❌176.9% higher power demand at 180W vs 65W.
❌Older platform position on TR4 with DDR4, while EPYC 4345P moves to AM5 and DDR5.
❌No integrated graphics, while EPYC 4345P can still boot and troubleshoot without a discrete GPU.

Quick Answers

So, is EPYC 4345P better than EPYC 7601?

Yes. EPYC 4345P is the better overall CPU here. You are getting a 59.4% average FPS lead across 4 shared CPU game tests in our data, 2.7% better PassMark, and the stronger long-term platform, which makes it the stronger all-around choice.

Which one is better for gaming?

If gaming is the priority, EPYC 4345P is the better pick here. According to our tests, it delivers 59.4% more average FPS across 4 shared CPU game tests.

Which one is better for streaming, content creation, and heavy multitasking?

For streaming, content creation, and heavier multitasking, EPYC 4345P is the better fit. You are getting 2.7% better PassMark, backed by 8 cores and 16 threads.

Which one is the smarter buy today, not just the cheaper CPU?

EPYC 4345P is the smarter buy today. EPYC 4345P is at an unclear MSRP at $329 MSRP versus unclear MSRP, and it gives you a 59.4% average FPS lead across 4 shared CPU game tests in our data. It is also 100.0% better value on MSRP (109.4 vs 0.0 PassMark/$), so the better CPU is not just faster, it is also the cleaner value play on paper.

Which one is more future-proof for 2026 and beyond?

EPYC 4345P is the more future-proof choice for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2017), a healthier platform with AM5 and DDR5 instead of TR4, more multi-core headroom with 8 cores / 16 threads instead of 32/64, and AVX-512 support for heavier modern compute workloads. That should give you a better long-term upgrade path for motherboard, RAM, and future CPU swaps.

Games Benchmarks

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

EPYC 4345P Benchmark Check

EPYC 7601 Benchmark Check

Path of Exile 2

Preset	EPYC 4345P	EPYC 7601
1080p
low	257 FPS	187 FPS
medium	239 FPS	165 FPS
high	207 FPS	132 FPS
ultra	178 FPS	105 FPS
1440p
low	220 FPS	153 FPS
medium	185 FPS	127 FPS
high	153 FPS	97 FPS
ultra	134 FPS	78 FPS
4K
low	153 FPS	71 FPS
medium	128 FPS	63 FPS
high	100 FPS	48 FPS
ultra	86 FPS	39 FPS

Open EPYC 4345P Open EPYC 7601

Path of Exile 2

Path of Exile 2

Counter-Strike 2

Preset	EPYC 4345P	EPYC 7601
1080p
low	630 FPS	207 FPS
medium	526 FPS	188 FPS
high	436 FPS	160 FPS
ultra	393 FPS	131 FPS
1440p
low	537 FPS	178 FPS
medium	470 FPS	163 FPS
high	395 FPS	141 FPS
ultra	337 FPS	111 FPS
4K
low	315 FPS	112 FPS
medium	281 FPS	103 FPS
high	265 FPS	92 FPS
ultra	232 FPS	75 FPS

Open EPYC 4345P Open EPYC 7601

Counter-Strike 2

Counter-Strike 2

League of Legends

Preset	EPYC 4345P	EPYC 7601
1080p
low	900 FPS	620 FPS
medium	747 FPS	518 FPS
high	664 FPS	466 FPS
ultra	570 FPS	399 FPS
1440p
low	725 FPS	517 FPS
medium	581 FPS	432 FPS
high	504 FPS	378 FPS
ultra	425 FPS	325 FPS
4K
low	501 FPS	383 FPS
medium	415 FPS	308 FPS
high	373 FPS	270 FPS
ultra	311 FPS	220 FPS

Open EPYC 4345P Open EPYC 7601

League of Legends

League of Legends

Valorant

Preset	EPYC 4345P	EPYC 7601
1080p
low	900 FPS	832 FPS
medium	900 FPS	759 FPS
high	856 FPS	652 FPS
ultra	772 FPS	565 FPS
1440p
low	855 FPS	666 FPS
medium	756 FPS	584 FPS
high	663 FPS	500 FPS
ultra	579 FPS	422 FPS
4K
low	570 FPS	474 FPS
medium	509 FPS	427 FPS
high	459 FPS	375 FPS
ultra	400 FPS	322 FPS

Open EPYC 4345P Open EPYC 7601

Valorant

Valorant

Check FPS for your specific build

Technical Specifications

Side-by-side comparison of EPYC 4345P and EPYC 7601

EPYC 4345P

The EPYC 4345P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 8 cores and 16 threads. Base frequency is 3.8 GHz, with boost up to 5.5 GHz. L3 cache: 32 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 36,006 points. Launch price was $329.

EPYC 7601

The EPYC 7601 is manufactured by AMD. It was released in 29 June 2017 (8 years ago). It is based on the Naples (2017−2018) architecture. It features 32 cores and 64 threads. Base frequency is 2.2 GHz, with boost up to 3.2 GHz. L3 cache: 64 MB (total). L2 cache: 512K (per core). Built on 14 nm process technology. Socket: TR4. Thermal design power (TDP): 180 Watt. Memory support: DDR4 Eight-channel. Passmark benchmark score: 35,059 points. Launch price was $4,200.

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Processing Power

The EPYC 4345P packs 8 cores / 16 threads, while the EPYC 7601 offers 32 cores / 64 threads — the EPYC 7601 has 24 more cores. Boost clocks reach 5.5 GHz on the EPYC 4345P versus 3.2 GHz on the EPYC 7601 — a 52.9% clock advantage for the EPYC 4345P (base: 3.8 GHz vs 2.2 GHz). The EPYC 4345P uses the Grado (2025) architecture (4 nm), while the EPYC 7601 uses Naples (2017−2018) (14 nm). In PassMark, the EPYC 4345P scores 36,006 against the EPYC 7601's 35,059 — a 2.7% lead for the EPYC 4345P. L3 cache: 32 MB (total) on the EPYC 4345P vs 64 MB (total) on the EPYC 7601.

Feature	EPYC 4345P	EPYC 7601
Cores / Threads	8 / 16	32 / 64+300%
Boost Clock	5.5 GHz+72%	3.2 GHz
Base Clock	3.8 GHz+73%	2.2 GHz
L3 Cache	32 MB (total)	64 MB (total)+100%
L2 Cache	1 MB (per core)+100%	512K (per core)
Process	4 nm-71%	14 nm
Architecture	Grado (2025)	Naples (2017−2018)
PassMark	36,006+3%	35,059

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Memory & Platform

The EPYC 4345P uses the AM5 socket (PCIe 4.0), while the EPYC 7601 uses TR4 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4345P versus 2666 on the EPYC 7601 — the EPYC 4345P supports 71% faster memory, which can translate to measurable gains in memory-sensitive workloads. The EPYC 7601 supports up to 2048 of RAM compared to 128 — 176.5% more capacity for professional workloads. Memory channels: 2 (EPYC 4345P) vs 8 (EPYC 7601). PCIe lanes: 28 (EPYC 4345P) vs 128 (EPYC 7601) — the EPYC 7601 offers 100 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4345P) and SP3 (EPYC 7601).

Feature	EPYC 4345P	EPYC 7601
Socket	AM5	TR4
PCIe Generation	PCIe 4.0	PCIe 4.0
Max RAM Speed	5600+110%	2666
Max RAM Capacity	128	2048+1500%
RAM Channels	2	8+300%
ECC Support	Yes	Yes
PCIe Lanes	28	128+357%

🔧

Advanced Features

Neither processor supports overclocking. Only the EPYC 4345P supports AVX-512 instructions — important for machine learning and scientific applications. Virtualization support: AMD-V, IOMMU (EPYC 4345P) vs AMD-V, SVM (EPYC 7601). The EPYC 4345P includes integrated graphics (AMD Radeon Graphics), while the EPYC 7601 requires a dedicated GPU. Direct competitor: EPYC 4345P rivals Xeon E-2488; EPYC 7601 rivals Xeon Platinum 8180.