EPYC 4345P
VS
Xeon Platinum 8280

EPYC 4345P vs Xeon Platinum 8280

AMD

EPYC 4345P

8 Cores16 Thrd65 WWMax: 5.5 GHz2025
VS
Intel

Xeon Platinum 8280

28 Cores56 Thrd205 WWMax: 4 GHz2019

Performance Spectrum - CPU

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

Value Upgrade Path

This is the official ChipVERSUS Value Rating, comparing raw performance (PassMark) per dollar. Components placed above yours deliver better value for money.

MSRP is the manufacturer's suggested retail price.
Avg price is the current average price collected from markets across the web.

Performance Per Dollar EPYC 4345P

#50
Xeon Gold 6238R
MSRP: $2612|Avg: N/A
133%
#54
EPYC 4465P
MSRP: $399|Avg: $399
115%
#55
Ryzen 5 PRO 7645
MSRP: $229|Avg: $192
110%
#56
Xeon E5-4667 v3
MSRP: $128|Avg: $128
110%
#59
Ryzen 9 PRO 7945
MSRP: $409|Avg: $450
105%
#60
Xeon Platinum 8571N
MSRP: $599|Avg: $418
104%
#61
Xeon Platinum 8270
MSRP: $7405|Avg: N/A
104%
#62
EPYC 4464P
MSRP: $429|Avg: $450
101%
#63
EPYC 4345P
MSRP: $329|Avg: $329
100%
#64
EPYC 4344P
MSRP: $329|Avg: $314
98%
#65
EPYC 4364P
MSRP: $399|Avg: $334
93%
#66
EPYC 4585PX
MSRP: $699|Avg: $826
92%
#67
EPYC 4545P
MSRP: $549|Avg: $595
90%
#71
Ryzen 7 PRO 7745
MSRP: $400|Avg: $343
80%
#73
EPYC 4484PX
MSRP: $599|Avg: $599
77%
Based on actual market prices and performance synthetic scores.

Performance Per Dollar Xeon Platinum 8280

#524
Xeon E7-4880 v2
MSRP: $6619|Avg: $185
199%
#524
Xeon E5-2675 V3
MSRP: $1800|Avg: $100
199%
#524
Xeon E5-2676 V3
MSRP: $1800|Avg: $36
199%
#527
Xeon Platinum 8592+
MSRP: $11600|Avg: $11600
197%
#528
Xeon E5-2687W v3
MSRP: $2141|Avg: $749
185%
#529
Xeon Max 9480
MSRP: $12980|Avg: $12980
174%
#530
Xeon E5-2689 v4
MSRP: $2723|Avg: $100
170%
#531
EPYC 7543
MSRP: $10257|Avg: $468
167%
#532
Xeon Platinum 8368Q
MSRP: $7719|Avg: $7719
164%
#533
Xeon Gold 6250
MSRP: $3400|Avg: $2000
164%
#534
Xeon E5-2699 v4
MSRP: $4115|Avg: $400
163%
#535
Xeon W-3245M
MSRP: $5002|Avg: $5002
155%
#536
Xeon W-3265M
MSRP: $6300|Avg: $3500
153%
#537
Xeon Platinum 8180
MSRP: $10009|Avg: $2363
104%
#538
Xeon Platinum 8280M
MSRP: $10009|Avg: $6223
102%
#539
Xeon Platinum 8280
MSRP: $10009|Avg: $2940
100%
#540
Xeon E7-8891 v3
MSRP: $6841|Avg: $418
86%
#541
Xeon E5-4669 v4
MSRP: $7007|Avg: $300
68%
Based on actual market prices and performance synthetic scores.

Performance Comparison

About PassMark

🏆 Chipversus Verdict

🚀 Performance Leadership

Generational Difference: This comparison involves processors from different technological eras. The EPYC 4345P (2025) utilizes 4 nm technology and DDR5, providing a fundamental performance advantage.
InsightEPYC 4345PXeon Platinum 8280
Gaming
Superior gaming performance
Lower gaming performance
Workstation
Weaker in multi-core tasks
Better multi-core power
Price
More affordable ($329)
⚠️ Higher cost ($2,940)
Longevity
✨ Modern (Grado (2025) / 4 nm)
✨ Modern (Cascade Lake-SP (2018) / 14 nm)

💎 Value Proposition

The Xeon Platinum 8280 (2019) relies on 14 nm technology and DDR4-2933, placing it in a different performance category relative to modern standards.
InsightEPYC 4345PXeon Platinum 8280
Cost Efficiency
Better overall value (+774%)
Lower cost efficiency
Upfront Cost
More affordable ($329)
⚠️ Higher cost ($2,940)

Performance Check

Paired with RTX 4090

To accurately isolate CPU performance, all benchmarks below use an NVIDIA RTX 4090 as the reference GPU. This eliminates GPU-side bottlenecks and highlights pure processing throughput differences between the CPUs.

Note: Real-world results may vary based on your actual GPU. CPU performance impact is more visible in processing-intensive titles and high-refresh-rate gaming scenarios.

Technical Specifications

Side-by-side comparison of EPYC 4345P and Xeon Platinum 8280

AMD

EPYC 4345P

The EPYC 4345P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 8 cores and 16 threads. Base frequency is 3.8 GHz, with boost up to 5.5 GHz. L3 cache: 32 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 36,006 points. Launch price was $329.

Intel

Xeon Platinum 8280

The Xeon Platinum 8280 is manufactured by Intel. It was released in 11 December 2018 (6 years ago). It is based on the Cascade Lake-SP (2018) architecture. It features 28 cores and 56 threads. Base frequency is 2.7 GHz, with boost up to 4 GHz. L3 cache: 38.5 MB (total). L2 cache: 1 MB (per core). Built on 14 nm process technology. Socket: LGA3647. Thermal design power (TDP): 205 Watt. Memory support: DDR4-2933. Passmark benchmark score: 36,830 points. Launch price was $10,009.

Processing Power

The EPYC 4345P packs 8 cores / 16 threads, while the Xeon Platinum 8280 offers 28 cores / 56 threads — the Xeon Platinum 8280 has 20 more cores. Boost clocks reach 5.5 GHz on the EPYC 4345P versus 4 GHz on the Xeon Platinum 8280 — a 31.6% clock advantage for the EPYC 4345P (base: 3.8 GHz vs 2.7 GHz). The EPYC 4345P uses the Grado (2025) architecture (4 nm), while the Xeon Platinum 8280 uses Cascade Lake-SP (2018) (14 nm). In PassMark, the EPYC 4345P scores 36,006 against the Xeon Platinum 8280's 36,830 — a 2.3% lead for the Xeon Platinum 8280. L3 cache: 32 MB (total) on the EPYC 4345P vs 38.5 MB (total) on the Xeon Platinum 8280.

FeatureEPYC 4345PXeon Platinum 8280
Cores / Threads
8 / 16
28 / 56+250%
Boost Clock
5.5 GHz+38%
4 GHz
Base Clock
3.8 GHz+41%
2.7 GHz
L3 Cache
32 MB (total)
38.5 MB (total)+20%
L2 Cache
1 MB (per core)
1 MB (per core)
Process
4 nm-71%
14 nm
Architecture
Grado (2025)
Cascade Lake-SP (2018)
PassMark
36,006
36,830+2%
🧠

Memory & Platform

The EPYC 4345P uses the AM5 socket (PCIe 4.0), while the Xeon Platinum 8280 uses LGA3647 (PCIe 3.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4345P versus 2933 on the Xeon Platinum 8280 — the EPYC 4345P supports 62.5% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon Platinum 8280 supports up to 1536 of RAM compared to 128 169.2% more capacity for professional workloads. Memory channels: 2 (EPYC 4345P) vs 6 (Xeon Platinum 8280). PCIe lanes: 28 (EPYC 4345P) vs 48 (Xeon Platinum 8280) — the Xeon Platinum 8280 offers 20 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4345P) and LGA3647 (Xeon Platinum 8280).

FeatureEPYC 4345PXeon Platinum 8280
Socket
AM5
LGA3647
PCIe Generation
PCIe 4.0+33%
PCIe 3.0
Max RAM Speed
5600+91%
2933
Max RAM Capacity
128
1536+1100%
RAM Channels
2
6+200%
ECC Support
PCIe Lanes
28
48+71%
🔧

Advanced Features

Neither processor supports overclocking. Both support AVX-512 instructions, benefiting scientific computing, AI inference, and encryption workloads. Virtualization support: AMD-V, IOMMU (EPYC 4345P) vs VT-x, VT-d (Xeon Platinum 8280). The EPYC 4345P includes integrated graphics (AMD Radeon Graphics), while the Xeon Platinum 8280 requires a dedicated GPU. Direct competitor: EPYC 4345P rivals Xeon E-2488; Xeon Platinum 8280 rivals EPYC 7702.

FeatureEPYC 4345PXeon Platinum 8280
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
None
Unlocked
No
No
AVX-512
Yes
Yes
Virtualization
AMD-V, IOMMU
VT-x, VT-d
💰

Value Analysis

The EPYC 4345P launched at $329 MSRP, while the Xeon Platinum 8280 debuted at $10009. At current prices ($329 vs $2940), the EPYC 4345P is $2611 cheaper. In terms of value (PassMark points per dollar), the EPYC 4345P delivers 109.4 pts/$ vs 12.5 pts/$ for the Xeon Platinum 8280 — making the EPYC 4345P the 158.9% better value option.

FeatureEPYC 4345PXeon Platinum 8280
MSRP
$329-97%
$10009
Avg Price (30d)
$329-89%
$2940
Performance per Dollar
109.4+775%
12.5
Release Date
2025
2019