EPYC 4345P vs Xeon Gold 5416S

AMD

EPYC 4345P

8 Cores16 Thrd65 WWMax: 5.5 GHz2025
EPYC family
·······
VS
Intel

Xeon Gold 5416S

16 Cores32 Thrd150 WWMax: 4 GHz2023
Similar parts
·······

EPYC 4345P vs Xeon Gold 5416S Performance Spectrum

About PassMark

PassMark CPU Mark evaluates processor speed through complex mathematical computations. It provides a reliable metric to compare multi-core performance, where higher scores indicate faster processing for multitasking, gaming, and heavy workloads.

EPYC 4345P vs Xeon Gold 5416S FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with GeForce RTX 5090 to isolate CPU performance.

Search any supported game below to compare 1080p FPS for both components.

EPYC 4345P vs Xeon Gold 5416S: Pros, Cons & Final Verdict

See where each CPU makes more sense in practice: gaming, heavier work, platform cost, power draw, and upgrade path.

EPYC 4345P

2025

Why buy it

  • Better for gaming: +14.8% higher average FPS across 50 shared CPU benchmark tests.
  • Costs $1,116 less on MSRP ($329 MSRP vs $1,445 MSRP).
  • Delivers 345.3% more PassMark for each dollar spent, at 109.4 vs 24.6 PassMark/$ ($329 MSRP vs $1,445 MSRP).
  • Draws 65W instead of 150W, a 85W reduction.
  • Integrated graphics onboard with AMD Radeon Graphics, while Xeon Gold 5416S needs a discrete GPU.

Trade-offs

  • Fewer obvious downsides in this matchup outside of normal market pricing swings.

Xeon Gold 5416S

2023

Why buy it

  • 185.7% more PCIe lanes (80 vs 28) for storage and expansion-heavy builds.

Trade-offs

  • Worse for gaming: lower average FPS than EPYC 4345P across 50 shared CPU benchmark tests.
  • Lower PassMark (35,515 vs 36,006).
  • Lower PassMark per dollar, at 24.6 vs 109.4 PassMark/$ ($1,445 MSRP vs $329 MSRP).
  • 130.8% higher power demand at 150W vs 65W.
  • No integrated graphics, while EPYC 4345P can still boot and troubleshoot without a discrete GPU.

Quick Answers

So, is EPYC 4345P better than Xeon Gold 5416S?
Yes. EPYC 4345P is the better all-around CPU here. It gives you a 14.8% average FPS lead across 50 shared CPU game tests in our data, 1.4% better PassMark, and the stronger long-term platform, which is enough to make it the stronger overall pick.
Which one is better for gaming?
If gaming is the priority, EPYC 4345P is the better pick. According to our tests, it delivers 14.8% more average FPS across 50 shared CPU game tests.
Which one is better for streaming, content creation, and heavy multitasking?
For streaming, content creation, and heavier multitasking, EPYC 4345P is the stronger fit. You are getting 1.4% better PassMark, backed by 8 cores and 16 threads.
Which one is the smarter buy today, not just the cheaper CPU?
EPYC 4345P is the better buy right now. EPYC 4345P comes in $1,116 cheaper on MSRP at $329 MSRP versus $1,445 MSRP, and it still gives you a 14.8% average FPS lead across 50 shared CPU game tests in our data. It is also 345.3% better value on MSRP (109.4 vs 24.6 PassMark/$), so you are getting the faster CPU without taking a value hit on paper.
Which one is more future-proof for 2026 and beyond?
EPYC 4345P makes more sense long term for 2026 and beyond. You are getting a newer CPU generation (2025 vs 2023) and more multi-core headroom with 8 cores / 16 threads instead of 16/32. That gives you a healthier platform runway for motherboard, RAM, and later CPU upgrades.

EPYC 4345P vs Xeon Gold 5416S Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

AMD

EPYC 4345P

The EPYC 4345P is manufactured by AMD. It was released in 13 May 2025 (less than a year ago). It is based on the Grado (2025) architecture. It features 8 cores and 16 threads. Base frequency is 3.8 GHz, with boost up to 5.5 GHz. L3 cache: 32 MB (total). L2 cache: 1 MB (per core). Built on 4 nm process technology. Socket: AM5. Thermal design power (TDP): 65 Watt. Memory support: DDR5. Passmark benchmark score: 36,006 points. Launch price was $329.

Intel

Xeon Gold 5416S

The Xeon Gold 5416S is manufactured by Intel. It was released in 10 January 2023 (2 years ago). It is based on the Sapphire Rapids (2023−2024) architecture. It features 16 cores and 32 threads. Base frequency is 2 GHz, with boost up to 4 GHz. L3 cache: 30 MB. L2 cache: 2 MB (per core). Built on Intel 7 nm process technology. Socket: LGA4677. Thermal design power (TDP): 150 Watt. Memory support: DDR5-4400. Passmark benchmark score: 35,515 points. Launch price was $944.

Processing Power

The EPYC 4345P packs 8 cores / 16 threads, while the Xeon Gold 5416S offers 16 cores / 32 threads — the Xeon Gold 5416S has 8 more cores. Boost clocks reach 5.5 GHz on the EPYC 4345P versus 4 GHz on the Xeon Gold 5416S — a 31.6% clock advantage for the EPYC 4345P (base: 3.8 GHz vs 2 GHz). The EPYC 4345P uses the Grado (2025) architecture (4 nm), while the Xeon Gold 5416S uses Sapphire Rapids (2023−2024) (Intel 7 nm). In PassMark, the EPYC 4345P scores 36,006 against the Xeon Gold 5416S's 35,515 — a 1.4% lead for the EPYC 4345P. L3 cache: 32 MB (total) on the EPYC 4345P vs 30 MB on the Xeon Gold 5416S.

FeatureEPYC 4345PXeon Gold 5416S
Cores / Threads
8 / 16
16 / 32+100%
Boost Clock
5.5 GHz+38%
4 GHz
Base Clock
3.8 GHz+90%
2 GHz
L3 Cache
32 MB (total)+7%
30 MB
L2 Cache
1 MB (per core)
2 MB (per core)+100%
Process
4 nm-43%
Intel 7 nm
Architecture
Grado (2025)
Sapphire Rapids (2023−2024)
PassMark
36,006+1%
35,515
🧠

Memory & Platform

The EPYC 4345P uses the AM5 socket (PCIe 4.0), while the Xeon Gold 5416S uses LGA4677 (PCIe 4.0) — making them incompatible on the same motherboard. Maximum memory speed reaches 5600 on the EPYC 4345P versus 4400 on the Xeon Gold 5416S — the EPYC 4345P supports 27.3% faster memory, which can translate to measurable gains in memory-sensitive workloads. The Xeon Gold 5416S supports up to 4096 of RAM compared to 128 3100% more capacity for professional workloads. Memory channels: 2 (EPYC 4345P) vs 8 (Xeon Gold 5416S). PCIe lanes: 28 (EPYC 4345P) vs 80 (Xeon Gold 5416S) — the Xeon Gold 5416S offers 52 more lanes for additional GPUs or NVMe drives. Chipset compatibility: AM5 (EPYC 4345P) and LGA4677 (Xeon Gold 5416S).

FeatureEPYC 4345PXeon Gold 5416S
Socket
AM5
LGA4677
PCIe Generation
PCIe 4.0
PCIe 4.0
Max RAM Speed
5600+27%
4400
Max RAM Capacity
128
4096+3100%
RAM Channels
2
8+300%
ECC Support
Yes
Yes
PCIe Lanes
28
80+186%
🔧

Advanced Features

Neither processor supports overclocking. Both support AVX-512 instructions, benefiting scientific computing, AI inference, and encryption workloads. Virtualization support: AMD-V, IOMMU (EPYC 4345P) vs VT-x, VT-d (Xeon Gold 5416S). The EPYC 4345P includes integrated graphics (AMD Radeon Graphics), while the Xeon Gold 5416S requires a dedicated GPU. Direct competitor: EPYC 4345P rivals Xeon E-2488; Xeon Gold 5416S rivals EPYC 8124P.

FeatureEPYC 4345PXeon Gold 5416S
Integrated GPU
Yes
No
IGPU Model
AMD Radeon Graphics
None
Unlocked
No
No
AVX-512
Yes
Yes
Virtualization
AMD-V, IOMMU
VT-x, VT-d
💰

Value Analysis

At launch, the EPYC 4345P was priced at $329, while the Xeon Gold 5416S came in at $1445. On launch pricing ($329 vs $1445), EPYC 4345P was $1116 cheaper. In terms of value on MSRP (PassMark points per dollar), the EPYC 4345P delivers 109.4 pts/$ vs 24.6 pts/$ for the Xeon Gold 5416S — making the EPYC 4345P the 126.6% better value option.

FeatureEPYC 4345PXeon Gold 5416S
MSRP
$329-77%
$1445
Performance per Dollar
109.4+345%
24.6
Release Date
2025
2023

Affiliate Disclosure

ChipVERSUS is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com. We may earn a commission on qualifying purchases made through our links. This comes at no additional cost to you and helps support our work in providing comprehensive PC building guides and tools.

Amazon and the Amazon logo are trademarks of Amazon.com, Inc. or its affiliates.