Quadro GP100 vs Radeon Pro Vega 64X

NVIDIA

Quadro GP100

2016Core: 1304 MHzBoost: 1442 MHz
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VS
AMD

Radeon Pro Vega 64X

2019Core: 1250 MHzBoost: 1468 MHz
Similar parts
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Quadro GP100 vs Radeon Pro Vega 64X Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro GP100 vs Radeon Pro Vega 64X FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro GP100 vs Radeon Pro Vega 64X: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro GP100

2016

Why buy it

  • 43.8% more average FPS across 50 tracked games in our benchmark data.
  • 100+% more VRAM for high-resolution textures and newer games (16 GB vs Unknown).
  • Radeon Pro Vega 64X is already legacy-tier future-proofing, so Quadro GP100 is the less risky modern option long term.

Trade-offs

  • 2016 hardware with 16 GB of VRAM already sits in legacy territory for modern games.
  • 218.2% HIGHER MSRP
    $7,000 MSRPvs$2,200 MSRP
  • Lower G3D Mark per dollar, at 2.0 vs 6.1 G3D/$ ($7,000 MSRP vs $2,200 MSRP).

Radeon Pro Vega 64X

2019

Why buy it

  • Costs $4,800 less on MSRP ($2,200 MSRP vs $7,000 MSRP).
  • Delivers 210.3% more G3D Mark for each dollar spent, at 6.1 vs 2.0 G3D/$ ($2,200 MSRP vs $7,000 MSRP).
  • More future proof: GCN 5.0 (2017−2020) on 14nm with a newer platform for upcoming games.

Trade-offs

  • Lower average FPS than Quadro GP100 across 50 tracked games in our benchmark data.
  • Less VRAM, with Unknown vs 16 GB for high-resolution textures and newer games.
  • 2019 hardware with Unknown of VRAM already sits in legacy territory for modern games.

Quick Answers

Which GPU is faster for gaming right now?
Quadro GP100 is the faster gaming card right now. In our data, it leads by 43.8% in average FPS across 50 tracked games in our benchmark data and by 2.6% in PassMark G3D (13,710 vs 13,369), so the answer here is pretty clean.
Which GPU is the safer long-term pick for 2026 and beyond?
Quadro GP100 is the safer long-term pick for 2026 and beyond. The case is simple: 16 GB vs Unknown of VRAM. That gives it more room for heavier textures and higher settings over time.
Which GPU is the better buy today?
Radeon Pro Vega 64X makes the most sense to buy today. It is $4,800 cheaper on MSRP at $2,200 vs $7,000, and it leads G3D-per-dollar by 210.3% (6.1 vs 2.0), which is enough to swing the recommendation its way. If you are mainly targeting 1080p and lighter 1440p, Radeon Pro Vega 64X is the easier value choice. If you care more about 1080p and lighter 1440p headroom, Quadro GP100 has the stronger long-term case.

Quadro GP100 vs Radeon Pro Vega 64X Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro GP100

The Quadro GP100 is manufactured by NVIDIA. It was released in October 1 2016. It features the Pascal architecture. The core clock ranges from 1304 MHz to 1442 MHz. It has 3584 shading units. The thermal design power (TDP) is 235W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 13,710 points.

AMD

Radeon Pro Vega 64X

The Radeon Pro Vega 64X is manufactured by AMD. It was released in March 19 2019. It features the GCN 5.0 architecture. The core clock ranges from 1250 MHz to 1468 MHz. It has 4096 shading units. The thermal design power (TDP) is 250W. Manufactured using 14 nm process technology. G3D Mark benchmark score: 13,369 points.

Graphics Performance

The Quadro GP100 scores 13,710 and the Radeon Pro Vega 64X reaches 13,369 in the G3D Mark benchmark — just a 2.6% difference, making them near-identical in rasterization performance. The Quadro GP100 is built on Pascal while the Radeon Pro Vega 64X uses GCN 5.0, both on 16 nm vs 14 nm. Shader units: 3,584 (Quadro GP100) vs 4,096 (Radeon Pro Vega 64X). Raw compute: 10.34 TFLOPS (Quadro GP100) vs 12.03 TFLOPS (Radeon Pro Vega 64X). Boost clocks: 1442 MHz vs 1468 MHz.

FeatureQuadro GP100Radeon Pro Vega 64X
G3D Mark Score
13,710+3%
13,369
Architecture
Pascal
GCN 5.0
Process Node
16 nm
14 nm
Shading Units
3584
4096+14%
Compute (TFLOPS)
10.34 TFLOPS
12.03 TFLOPS+16%
Boost Clock
1442 MHz
1468 MHz+2%
ROPs
96+50%
64
TMUs
224
256+14%
L1 Cache
1.3 MB+30%
1 MB
L2 Cache
4 MB
4 MB

Advanced Features (DLSS/FSR)

FeatureQuadro GP100Radeon Pro Vega 64X
Upscaling Tech
Upscaling support
FSR Upscaling / FSR 4
Frame Generation
Not Supported
Not Supported
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro GP100 has 16 GB of VRAM, while the Radeon Pro Vega 64X carries 0 MB. Quadro GP100 gives you 100+% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bus width is 4096-bit on the Quadro GP100 and 128-bit on the Radeon Pro Vega 64X.

FeatureQuadro GP100Radeon Pro Vega 64X
VRAM Capacity
16 GB
Shared System RAM
Memory Type
HBM2
GDDR6
Bus Width
4096-bit+3100%
128-bit
L2 Cache
4 MB
4 MB
🖥️

Display & API Support

DirectX support: 12 (Quadro GP100) vs 12.1 (Radeon Pro Vega 64X). Vulkan: 1.3 vs 1.1. OpenGL: 4.5 vs 4.6. Maximum simultaneous displays: 4 vs 4.

FeatureQuadro GP100Radeon Pro Vega 64X
DirectX
12
12.1
Vulkan
1.3+18%
1.1
OpenGL
4.5
4.6+2%
Max Displays
4
4
🎬

Media & Encoding

Hardware encoder: NVENC 4th gen (Quadro GP100) vs VCE 4.0 (Radeon Pro Vega 64X). Decoder: NVDEC 3rd gen vs UVD 7.0. Supported codecs: H.264,H.265/HEVC,MPEG-2,VC-1,VP8,VP9 (Quadro GP100) vs MPEG-2,H.264,HEVC,VP9 (Radeon Pro Vega 64X).

FeatureQuadro GP100Radeon Pro Vega 64X
Encoder
NVENC 4th gen
VCE 4.0
Decoder
NVDEC 3rd gen
UVD 7.0
Codecs
H.264,H.265/HEVC,MPEG-2,VC-1,VP8,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro GP100 draws 235W versus the Radeon Pro Vega 64X's 250W — a 6.2% difference. The Quadro GP100 is more power-efficient. Recommended PSU: 500W (Quadro GP100) vs 1W (Radeon Pro Vega 64X). Power connectors: PCIe-powered vs Integrated. Card length: 267mm vs 0mm, occupying 2 vs 0 slots. Typical load temperature: 80°C vs 85°C.

FeatureQuadro GP100Radeon Pro Vega 64X
TDP
235W-6%
250W
Recommended PSU
500W
1W-100%
Power Connector
PCIe-powered
Integrated
Length
267mm
0mm
Height
111mm
0mm
Slots
2
0-100%
Temp (Load)
80°C-6%
85°C
Perf/Watt
58.3+9%
53.5
💰

Value Analysis

At launch, the Quadro GP100 came in at $7000, while the Radeon Pro Vega 64X launched at $2200. On MSRP, Radeon Pro Vega 64X was 68.6% cheaper ($4800 less). Performance per dollar on MSRP (G3D Mark / MSRP): 2.0 (Quadro GP100) vs 6.1 (Radeon Pro Vega 64X) — the Radeon Pro Vega 64X offers 205% better value. The newer card here is Radeon Pro Vega 64X (2019 vs 2016).

FeatureQuadro GP100Radeon Pro Vega 64X
MSRP
$7000
$2200-69%
Performance per Dollar
2.0
6.1+205%
Codename
GP100
Vega 10
Release
October 1 2016
March 19 2019
Ranking
#178
#190

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