Quadro GP100 vs Radeon RX 6600M

NVIDIA

Quadro GP100

2016Core: 1304 MHzBoost: 1442 MHz
Similar parts
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VS
AMD

Radeon RX 6600M

2021Core: 2068 MHzBoost: 2416 MHz
Similar parts
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Quadro GP100 vs Radeon RX 6600M Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro GP100 vs Radeon RX 6600M FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro GP100 vs Radeon RX 6600M: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro GP100

2016

Why buy it

  • 13.9% more average FPS across 50 tracked games in our benchmark data.
  • Delivers 100+% more G3D Mark for each dollar spent, at 2.0 vs 0 G3D/$ ($7,000 MSRP vs Unknown MSRP).
  • 100% more VRAM for high-resolution textures and newer games (16 GB vs 8 GB).

Trade-offs

  • No equivalent frame-generation stack like FSR Frame Generation + AFMF (2023).
  • 2016 hardware with 16 GB of VRAM already sits in legacy territory for modern games.
  • 135% higher power demand at 235W vs 100W.

Radeon RX 6600M

2021

Why buy it

  • Access to a newer frame-generation stack with FSR Frame Generation + AFMF (2023).
  • Better long-term bet: RDNA 2.0 (2020−2025) on 7nm gives it a newer hardware base for upcoming games.
  • Draws 100W instead of 235W, a 135W reduction.

Trade-offs

  • Lower average FPS than Quadro GP100 across 50 tracked games in our benchmark data.
  • Less VRAM, with 8 GB vs 16 GB for high-resolution textures and newer games.
  • Lower G3D Mark per dollar, at 0 vs 2.0 G3D/$ (Unknown MSRP vs $7,000 MSRP).

Quick Answers

Which GPU is faster for gaming right now?
Quadro GP100 is the faster gaming card right now. In our data, it leads by 13.9% in average FPS across 50 tracked games in our benchmark data. PassMark G3D leans toward Radeon RX 6600M instead at 13,922 vs 13,710, so for this question the real-game FPS result matters more than the synthetic split.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon RX 6600M is the safer long-term pick for 2026 and beyond. The case is simple: the newer feature stack, with FSR 3 (2023) and FSR Frame Generation + AFMF (2023), while Quadro GP100 is limited to no meaningful modern upscaling stack and no comparable frame-generation support, a 7nm process instead of 16nm, 28 vs 0 ray-tracing units, and a newer 2021 generation instead of 2016. That gives it the more rounded hardware package for newer games.
Which GPU is the better buy today?
Quadro GP100 makes the most sense today based on the pricing and value data we have for this matchup. If you are mainly targeting 1080p and lighter 1440p, Quadro GP100 is the easier value choice. If you care more about 1080p and lighter 1440p headroom, Radeon RX 6600M has the stronger long-term case.

Quadro GP100 vs Radeon RX 6600M Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro GP100

The Quadro GP100 is manufactured by NVIDIA. It was released in October 1 2016. It features the Pascal architecture. The core clock ranges from 1304 MHz to 1442 MHz. It has 3584 shading units. The thermal design power (TDP) is 235W. Manufactured using 16 nm process technology. G3D Mark benchmark score: 13,710 points.

AMD

Radeon RX 6600M

The Radeon RX 6600M is manufactured by AMD. It was released in May 31 2021. It features the RDNA 2.0 architecture. The core clock ranges from 2068 MHz to 2416 MHz. It has 1792 shading units. The thermal design power (TDP) is 100W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 13,922 points.

Graphics Performance

The Quadro GP100 scores 13,710 and the Radeon RX 6600M reaches 13,922 in the G3D Mark benchmark — just a 1.5% difference, making them near-identical in rasterization performance. The Quadro GP100 is built on Pascal while the Radeon RX 6600M uses RDNA 2.0, both on 16 nm vs 7 nm. Shader units: 3,584 (Quadro GP100) vs 1,792 (Radeon RX 6600M). Raw compute: 10.34 TFLOPS (Quadro GP100) vs 8.659 TFLOPS (Radeon RX 6600M). Boost clocks: 1442 MHz vs 2416 MHz.

FeatureQuadro GP100Radeon RX 6600M
G3D Mark Score
13,710
13,922+2%
Architecture
Pascal
RDNA 2.0
Process Node
16 nm
7 nm
Shading Units
3584+100%
1792
Compute (TFLOPS)
10.34 TFLOPS+19%
8.659 TFLOPS
Boost Clock
1442 MHz
2416 MHz+68%
ROPs
96+50%
64
TMUs
224+100%
112
L1 Cache
1.3 MB+160%
0.5 MB
L2 Cache
4 MB+100%
2 MB

Advanced Features (DLSS/FSR)

The clearest feature edge for the Radeon RX 6600M is support for FSR Frame Generation + AFMF. In games that support it, that can smooth out motion and lift perceived FPS. The Quadro GP100 does not have comparable native support in the same tier.

FeatureQuadro GP100Radeon RX 6600M
Upscaling Tech
Upscaling support
FSR 3
Frame Generation
Not Supported
FSR Frame Generation + AFMF
Ray Reconstruction
No
No
Low Latency
Standard
AMD Anti-Lag
💾

Video Memory (VRAM)

The Quadro GP100 has 16 GB of VRAM, while the Radeon RX 6600M carries 8 GB. Quadro GP100 gives you 100% more memory capacity, which matters more once you move into heavier textures, mods, or higher resolutions. Memory bandwidth: 1024 GB/s (Quadro GP100) vs 224 GB/s (Radeon RX 6600M) — a 357.1% advantage for the Quadro GP100. Memory bus width is 4096-bit on the Quadro GP100 and 128-bit on the Radeon RX 6600M. L2 Cache: 4 MB (Quadro GP100) vs 2 MB (Radeon RX 6600M) — the Quadro GP100 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro GP100Radeon RX 6600M
VRAM Capacity
16 GB+100%
8 GB
Memory Type
HBM2
GDDR6
Memory Bandwidth
1024 GB/s+357%
224 GB/s
Bus Width
4096-bit+3100%
128-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12 (Quadro GP100) vs 12 (FL 12_2) (Radeon RX 6600M). Vulkan: 1.3 vs 1.3. OpenGL: 4.5 vs 4.6. Maximum simultaneous displays: 4 vs 4.

FeatureQuadro GP100Radeon RX 6600M
DirectX
12
12 (FL 12_2)
Vulkan
1.3
1.3
OpenGL
4.5
4.6+2%
Max Displays
4
4
🎬

Media & Encoding

Hardware encoder: NVENC 4th gen (Quadro GP100) vs VCN 3.0 (Radeon RX 6600M). Decoder: NVDEC 3rd gen vs VCN 3.0. Supported codecs: H.264,H.265/HEVC,MPEG-2,VC-1,VP8,VP9 (Quadro GP100) vs H.264,HEVC,VP9,AV1 (Radeon RX 6600M).

FeatureQuadro GP100Radeon RX 6600M
Encoder
NVENC 4th gen
VCN 3.0
Decoder
NVDEC 3rd gen
VCN 3.0
Codecs
H.264,H.265/HEVC,MPEG-2,VC-1,VP8,VP9
H.264,HEVC,VP9,AV1
🔌

Power & Dimensions

The Quadro GP100 draws 235W versus the Radeon RX 6600M's 100W — a 80.6% difference. The Radeon RX 6600M is more power-efficient. Recommended PSU: 500W (Quadro GP100) vs 500W (Radeon RX 6600M). Power connectors: PCIe-powered vs Mobile.

FeatureQuadro GP100Radeon RX 6600M
TDP
235W
100W-57%
Recommended PSU
500W
500W
Power Connector
PCIe-powered
Mobile
Length
267mm
Height
111mm
Slots
2
0-100%
Temp (Load)
80°C
Perf/Watt
58.3
139.2+139%
💰

Value Analysis

The newer card here is Radeon RX 6600M (2021 vs 2016).

FeatureQuadro GP100Radeon RX 6600M
MSRP
$7000
Codename
GP100
Navi 23
Release
October 1 2016
May 31 2021
Ranking
#178
#173

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