Quadro RTX 4000 vs Radeon RX 6650M

NVIDIA

Quadro RTX 4000

2018Core: 1005 MHzBoost: 1545 MHz
VS
AMD

Radeon RX 6650M

2022Core: 2068 MHzBoost: 2416 MHz

Quadro RTX 4000 vs Radeon RX 6650M Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro RTX 4000 vs Radeon RX 6650M FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro RTX 4000 vs Radeon RX 6650M: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro RTX 4000

2018

Why buy it

  • Delivers 100+% more G3D Mark for each dollar spent, at 16.6 vs 0 G3D/$ ($899 MSRP vs Unknown MSRP).

Trade-offs

  • Lower average FPS than Radeon RX 6650M across 50 tracked games in our benchmark data.
  • Radeon RX 6650M is the safer long-term pick here because the hardware is newer and the feature stack is stronger.
  • 33.3% higher power demand at 160W vs 120W.

Radeon RX 6650M

2022

Why buy it

  • 1.7% more average FPS across 50 tracked games in our benchmark data.
  • Better long-term bet: RDNA 2.0 on 7nm gives it a newer hardware base for upcoming games.
  • Draws 120W instead of 160W, a 40W reduction.

Trade-offs

  • Lower G3D Mark per dollar, at 0 vs 16.6 G3D/$ (Unknown MSRP vs $899 MSRP).

Quick Answers

Which GPU is faster for gaming right now?
Radeon RX 6650M is the faster gaming card right now. In our data, it leads by 1.7% in average FPS across 50 tracked games in our benchmark data and by 1.6% in PassMark G3D (15,171 vs 14,925), so the answer here is pretty clean.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon RX 6650M is the safer long-term pick for 2026 and beyond. The case is simple: a 7nm process instead of 12nm and a newer 2022 generation instead of 2018. That makes it the less risky pick as game demands keep moving.
Which GPU is the better buy today?
Quadro RTX 4000 makes the most sense today based on the pricing and value data we have for this matchup. If you are mainly targeting 1080p and lighter 1440p, Quadro RTX 4000 is the easier value choice. If you care more about 1080p and lighter 1440p headroom, Radeon RX 6650M has the stronger long-term case.

Quadro RTX 4000 vs Radeon RX 6650M Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro RTX 4000

The Quadro RTX 4000 is manufactured by NVIDIA. It was released in November 13 2018. It features the Turing architecture. The core clock ranges from 1005 MHz to 1545 MHz. It has 2304 shading units. The thermal design power (TDP) is 160W. Manufactured using 12 nm process technology. It features 36 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,925 points. Launch price was $899.

AMD

Radeon RX 6650M

The Radeon RX 6650M is manufactured by AMD. It was released in January 4 2022. It features the RDNA 2.0 architecture. The core clock ranges from 2068 MHz to 2416 MHz. It has 1792 shading units. The thermal design power (TDP) is 120W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 15,171 points.

Graphics Performance

The Quadro RTX 4000 scores 14,925 and the Radeon RX 6650M reaches 15,171 in the G3D Mark benchmark — just a 1.6% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 is built on Turing while the Radeon RX 6650M uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 2,304 (Quadro RTX 4000) vs 1,792 (Radeon RX 6650M). Raw compute: 7.119 TFLOPS (Quadro RTX 4000) vs 8.659 TFLOPS (Radeon RX 6650M). Boost clocks: 1545 MHz vs 2416 MHz. Ray tracing: 36 RT cores (Quadro RTX 4000) vs 28 (Radeon RX 6650M) with 288 Tensor cores.

FeatureQuadro RTX 4000Radeon RX 6650M
G3D Mark Score
14,925
15,171+2%
Architecture
Turing
RDNA 2.0
Process Node
12 nm
7 nm
Shading Units
2304+29%
1792
Compute (TFLOPS)
7.119 TFLOPS
8.659 TFLOPS+22%
Boost Clock
1545 MHz
2416 MHz+56%
ROPs
64
64
TMUs
144+29%
112
L1 Cache
2.3 MB+360%
0.5 MB
L2 Cache
4 MB+100%
2 MB
Ray Tracing Cores
36+29%
28

Advanced Features (DLSS/FSR)

Both GPUs support Frame Generation, but they get there through different ecosystems. The Quadro RTX 4000 uses DLSS 3.5 + Frame Generation, while the Radeon RX 6650M relies on FSR Frame Generation + AFMF. Both can help smooth out supported games, but they are not on the same feature stack.The Quadro RTX 4000 gets NVIDIA DLSS, which still tends to look cleaner in motion. The Radeon RX 6650M leans on FSR, which is flexible and widely supported, but usually a bit rougher at the same settings.

FeatureQuadro RTX 4000Radeon RX 6650M
Upscaling Tech
DLSS 3.5 Super Resolution
FSR 3
Frame Generation
DLSS 3.5 + Frame Generation
FSR Frame Generation + AFMF
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards ship with 8 GB of GDDR6. Memory bandwidth: 448 GB/s (Quadro RTX 4000) vs 224 GB/s (Radeon RX 6650M) — a 100% advantage for the Quadro RTX 4000. Memory bus width is 256-bit on the Quadro RTX 4000 and 128-bit on the Radeon RX 6650M. L2 Cache: 4 MB (Quadro RTX 4000) vs 2 MB (Radeon RX 6650M) — the Quadro RTX 4000 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000Radeon RX 6650M
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Memory Bandwidth
448 GB/s+100%
224 GB/s
Bus Width
256-bit+100%
128-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000) vs 12.2 (Radeon RX 6650M). Vulkan: 1.1 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 1.

FeatureQuadro RTX 4000Radeon RX 6650M
DirectX
12.2
12.2
Vulkan
1.1
1.4+27%
OpenGL
4.6
4.6
Max Displays
4+300%
1
🎬

Media & Encoding

Hardware encoder: NVENC 7.0 (Quadro RTX 4000) vs VCN 3.0 (Radeon RX 6650M). Decoder: PureVideo HD VP10 vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon RX 6650M).

FeatureQuadro RTX 4000Radeon RX 6650M
Encoder
NVENC 7.0
VCN 3.0
Decoder
PureVideo HD VP10
VCN 3.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro RTX 4000 draws 160W versus the Radeon RX 6650M's 120W — a 28.6% difference. The Radeon RX 6650M is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000) vs 650W (Radeon RX 6650M). Power connectors: PCIe-powered vs Mobile. Card length: 241mm vs 0mm, occupying 2 vs 0 slots. Typical load temperature: 80°C vs 80°C.

FeatureQuadro RTX 4000Radeon RX 6650M
TDP
160W
120W-25%
Recommended PSU
500W-23%
650W
Power Connector
PCIe-powered
Mobile
Length
241mm
0mm
Height
111mm
0mm
Slots
2
0-100%
Temp (Load)
80°C
80°C
Perf/Watt
93.3
126.4+35%
💰

Value Analysis

The newer card here is Radeon RX 6650M (2022 vs 2018).

FeatureQuadro RTX 4000Radeon RX 6650M
MSRP
$899
Codename
TU104
Navi 23
Release
November 13 2018
January 4 2022
Ranking
#154
#148

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