Quadro RTX 4000 vs Radeon PRO W6600

NVIDIA

Quadro RTX 4000

2018Core: 1005 MHzBoost: 1545 MHz
VS
AMD

Radeon PRO W6600

2021Core: 2331 MHzBoost: 2903 MHz

Quadro RTX 4000 vs Radeon PRO W6600 Performance Spectrum

About G3D Mark

G3D Mark is a standard benchmark that measures graphics performance in real-world gaming scenarios. It simplifies comparing cards from different brands, where higher scores directly correlate with better fps and smoother gaming experiences.

Quadro RTX 4000 vs Radeon PRO W6600 FPS Benchmarks

Predicted gaming performance across popular games. Tested paired with Ryzen 7 9800X3D to isolate GPU performance.

Search any supported game below to compare 1080p FPS for both components.

Quadro RTX 4000 vs Radeon PRO W6600: Pros, Cons & Final Verdict

See where each GPU makes more sense in practice: raw FPS, VRAM, features, power draw, pricing, and long-term headroom.

Quadro RTX 4000

2018

Why buy it

  • Access to a newer frame-generation stack with DLSS 3.5 + Frame Generation (2023).

Trade-offs

  • Lower average FPS than Radeon PRO W6600 across 50 tracked games in our benchmark data.
  • Radeon PRO W6600 is the safer long-term pick here because the hardware is newer and the feature stack is stronger.
  • 38.5% HIGHER MSRP
    $899 MSRPvs$649 MSRP
  • Lower G3D Mark per dollar, at 16.6 vs 23.0 G3D/$ ($899 MSRP vs $649 MSRP).
  • 60% higher power demand at 160W vs 100W.

Radeon PRO W6600

2021

Why buy it

  • 5.9% more average FPS across 50 tracked games in our benchmark data.
  • Costs $250 less on MSRP ($649 MSRP vs $899 MSRP).
  • Delivers 38.6% more G3D Mark for each dollar spent, at 23.0 vs 16.6 G3D/$ ($649 MSRP vs $899 MSRP).
  • Better long-term bet: RDNA 2.0 on 7nm gives it a newer hardware base for upcoming games.
  • Draws 100W instead of 160W, a 60W reduction.

Trade-offs

  • No equivalent frame-generation stack like DLSS 3.5 + Frame Generation (2023).

Quick Answers

Which GPU is faster for gaming right now?
Radeon PRO W6600 is the faster gaming card right now. In our data, it leads by 5.9% in average FPS across 50 tracked games in our benchmark data and by 0% in PassMark G3D (14,932 vs 14,925), so the answer here is pretty clean.
Which GPU is the safer long-term pick for 2026 and beyond?
Radeon PRO W6600 is the safer long-term pick for 2026 and beyond. The case is simple: the newer upscaling stack, FSR Upscaling / FSR 4 (2025) instead of DLSS 3.5 Super Resolution (2023), a 7nm process instead of 12nm, and a newer 2021 generation instead of 2018. That makes it the less risky pick as game demands keep moving.
Which GPU is the better buy today?
Radeon PRO W6600 makes the most sense to buy today. It is $250 cheaper on MSRP at $649 vs $899, and it leads G3D-per-dollar by 38.6% (23.0 vs 16.6), so the value case lines up with the gaming result.

Quadro RTX 4000 vs Radeon PRO W6600 Technical Specifications

Side-by-side specs, architecture details, clocks, memory, power, and platform differences.

NVIDIA

Quadro RTX 4000

The Quadro RTX 4000 is manufactured by NVIDIA. It was released in November 13 2018. It features the Turing architecture. The core clock ranges from 1005 MHz to 1545 MHz. It has 2304 shading units. The thermal design power (TDP) is 160W. Manufactured using 12 nm process technology. It features 36 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,925 points. Launch price was $899.

AMD

Radeon PRO W6600

The Radeon PRO W6600 is manufactured by AMD. It was released in June 8 2021. It features the RDNA 2.0 architecture. The core clock ranges from 2331 MHz to 2903 MHz. It has 1792 shading units. The thermal design power (TDP) is 100W. Manufactured using 7 nm process technology. It features 28 dedicated ray tracing cores for enhanced lighting effects. G3D Mark benchmark score: 14,932 points. Launch price was $649.

Graphics Performance

The Quadro RTX 4000 scores 14,925 and the Radeon PRO W6600 reaches 14,932 in the G3D Mark benchmark — just a 0% difference, making them near-identical in rasterization performance. The Quadro RTX 4000 is built on Turing while the Radeon PRO W6600 uses RDNA 2.0, both on 12 nm vs 7 nm. Shader units: 2,304 (Quadro RTX 4000) vs 1,792 (Radeon PRO W6600). Raw compute: 7.119 TFLOPS (Quadro RTX 4000) vs 10.4 TFLOPS (Radeon PRO W6600). Boost clocks: 1545 MHz vs 2903 MHz. Ray tracing: 36 RT cores (Quadro RTX 4000) vs 28 (Radeon PRO W6600) with 288 Tensor cores.

FeatureQuadro RTX 4000Radeon PRO W6600
G3D Mark Score
14,925
14,932
Architecture
Turing
RDNA 2.0
Process Node
12 nm
7 nm
Shading Units
2304+29%
1792
Compute (TFLOPS)
7.119 TFLOPS
10.4 TFLOPS+46%
Boost Clock
1545 MHz
2903 MHz+88%
ROPs
64
64
TMUs
144+29%
112
L1 Cache
2.3 MB+360%
0.5 MB
L2 Cache
4 MB+100%
2 MB
Ray Tracing Cores
36+29%
28

Advanced Features (DLSS/FSR)

The clearest feature edge for the Quadro RTX 4000 is support for DLSS 3.5 + Frame Generation. In games that support it, that can smooth out motion and lift perceived FPS. The Radeon PRO W6600 does not have comparable native support in the same tier.The Quadro RTX 4000 gets NVIDIA DLSS, which still tends to look cleaner in motion. The Radeon PRO W6600 leans on FSR, which is flexible and widely supported, but usually a bit rougher at the same settings.

FeatureQuadro RTX 4000Radeon PRO W6600
Upscaling Tech
DLSS 3.5 Super Resolution
FSR Upscaling / FSR 4
Frame Generation
DLSS 3.5 + Frame Generation
Not Supported
Ray Reconstruction
Yes (DLSS 3.5)
No
Low Latency
NVIDIA Reflex
AMD Anti-Lag
💾

Video Memory (VRAM)

Both cards ship with 8 GB of GDDR6. Memory bandwidth: 448 GB/s (Quadro RTX 4000) vs 224 GB/s (Radeon PRO W6600) — a 100% advantage for the Quadro RTX 4000. Memory bus width is 256-bit on the Quadro RTX 4000 and 256-bit on the Radeon PRO W6600. L2 Cache: 4 MB (Quadro RTX 4000) vs 2 MB (Radeon PRO W6600) — the Quadro RTX 4000 has significantly larger on-die cache to reduce VRAM reliance.

FeatureQuadro RTX 4000Radeon PRO W6600
VRAM Capacity
8 GB
8 GB
Memory Type
GDDR6
GDDR6
Memory Bandwidth
448 GB/s+100%
224 GB/s
Bus Width
256-bit
256-bit
L2 Cache
4 MB+100%
2 MB
🖥️

Display & API Support

DirectX support: 12.2 (Quadro RTX 4000) vs 12.2 (Radeon PRO W6600). Vulkan: 1.1 vs 1.4. OpenGL: 4.6 vs 4.6. Maximum simultaneous displays: 4 vs 3.

FeatureQuadro RTX 4000Radeon PRO W6600
DirectX
12.2
12.2
Vulkan
1.1
1.4+27%
OpenGL
4.6
4.6
Max Displays
4+33%
3
🎬

Media & Encoding

Hardware encoder: NVENC 7.0 (Quadro RTX 4000) vs VCN 3.0 (Radeon PRO W6600). Decoder: PureVideo HD VP10 vs VCN 3.0. Supported codecs: MPEG-2,H.264,HEVC,VP9 (Quadro RTX 4000) vs MPEG-2,H.264,HEVC,VP9 (Radeon PRO W6600).

FeatureQuadro RTX 4000Radeon PRO W6600
Encoder
NVENC 7.0
VCN 3.0
Decoder
PureVideo HD VP10
VCN 3.0
Codecs
MPEG-2,H.264,HEVC,VP9
MPEG-2,H.264,HEVC,VP9
🔌

Power & Dimensions

The Quadro RTX 4000 draws 160W versus the Radeon PRO W6600's 100W — a 46.2% difference. The Radeon PRO W6600 is more power-efficient. Recommended PSU: 500W (Quadro RTX 4000) vs 500W (Radeon PRO W6600). Power connectors: PCIe-powered vs PCIe-powered. Card length: 241mm vs 190mm, occupying 2 vs 2 slots. Typical load temperature: 80°C vs 75°C.

FeatureQuadro RTX 4000Radeon PRO W6600
TDP
160W
100W-38%
Recommended PSU
500W
500W
Power Connector
PCIe-powered
PCIe-powered
Length
241mm
190mm
Height
111mm
111mm
Slots
2
2
Temp (Load)
80°C
75°C-6%
Perf/Watt
93.3
149.3+60%
💰

Value Analysis

At launch, the Quadro RTX 4000 came in at $899, while the Radeon PRO W6600 launched at $649. On MSRP, Radeon PRO W6600 was 27.8% cheaper ($250 less). Performance per dollar on MSRP (G3D Mark / MSRP): 16.6 (Quadro RTX 4000) vs 23.0 (Radeon PRO W6600) — the Radeon PRO W6600 offers 38.6% better value. The newer card here is Radeon PRO W6600 (2021 vs 2018).

FeatureQuadro RTX 4000Radeon PRO W6600
MSRP
$899
$649-28%
Performance per Dollar
16.6
23.0+39%
Codename
TU104
Navi 23
Release
November 13 2018
June 8 2021
Ranking
#154
#153

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